Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alan George Porter"'
Publikováno v:
Bioscience Reports. 29:405-415
MST3 (mammalian sterile 20-like kinase 3) is a sterile 20 kinase reported to have a role in Fas-ligation- and staurosporine-induced cell death by unknown mechanism(s). We found that MST3-deficient cells are resistant to H 2 O 2 , which was reversed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b191c474ba82c81e5045292e483bf7
https://doi.org/10.1042/bsr20090096
https://doi.org/10.1042/bsr20090096
Autor:
Hwee Hong Tan, Alan George Porter
Publikováno v:
Biochemical and Biophysical Research Communications. 382:462-467
Doxorubicin can induce the formation of extra-nuclear bodies during mitosis termed micronuclei but the underlying causes remain unknown. Here, we show that sub-lethal exposure to doxorubicin-induced micronuclei formation in human cancer cells but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be81fbc760e36d8c19d5ccc95bb5c7a9
https://doi.org/10.1016/j.bbrc.2009.03.065
https://doi.org/10.1016/j.bbrc.2009.03.065
Autor:
Alan George Porter, Hwee Hong Tan
Publikováno v:
Biochemical and Biophysical Research Communications. 382:171-176
The expression of DNMT1, the major maintenance DNA methyltransferases, is critical in coordinating DNMT1 activity with biological processes and therefore must be tightly regulated in the cell cycle. Here, we report p21(WAF1) as a novel upstream regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf415199b869bed6ce916a85aa6f8b
https://doi.org/10.1016/j.bbrc.2009.03.001
https://doi.org/10.1016/j.bbrc.2009.03.001
Autor:
Andre M. Kallab, John T. Barrett, Jennifer N. Delk, Patricia V. Schoenlein, Virgil T. Gaddy, Alan George Porter
Publikováno v:
Clinical Cancer Research. 10:5215-5225
Purpose: A major clinical problem in the treatment of breast cancer is the inherent and acquired resistance to antiestrogen therapy. In this study, we sought to determine whether antiprogestin treatment, used as a monotherapy or in combination with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972100bd1ec0d93dcbbc3094fe1c413b
https://doi.org/10.1158/1078-0432.ccr-03-0637
https://doi.org/10.1158/1078-0432.ccr-03-0637
Publikováno v:
Nucleic Acids Research. 3:2789-2810
Encephalomyocarditis (EMC) virus RNA contains a covalently bound sequence of polyriboadenylic acid (poly(A). This was determined by two-dimensional gel electrophoresis of complete T1 and pancreatic RNase digests of formamidesucrose gradient-purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1564c43de0a6e82f9577f4c20c1a0389
https://doi.org/10.1093/nar/3.10.2789
https://doi.org/10.1093/nar/3.10.2789
Publikováno v:
Nature. 276:298-301
IN common with eukaryotic cellular mRNAs1–3, the terminal sequences in virus RNAs contain untranslated regions of variable length4–11. These regions are likely to contain binding sites for macromolecules involved in functions such as replication4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee922667aa5c7c1f0d14be7d4fa93379
https://doi.org/10.1038/276298a0
https://doi.org/10.1038/276298a0
Autor:
K. Dawson, C. Hynes, L. Dunthorne, Alan George Porter, William C.A. Tacon, J. Viney, N. Warburton, M. Finlay, S.M. Doel, M. Houghton, A.G. Stewart, M. Nugent, J.A. Davies, J.R. Adair, G.J. O'neill, L.D. Bell, J. Clarke, Keith Graham Mccullagh, R. Derbyshire, P.G. Boseley, J. Hall, I. Lindley, G. H. Catlin, J. C. Smith
Publikováno v:
DNA. 5:137-148
A series of novel, modified interferons based on the structure of human beta-interferon have been expressed in Escherichia coli. Modified interferon genes were constructed from sequences derived from the natural beta-interferon gene, a synthetic beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d374b390446bb21b7136c77b7e04ac8b
https://doi.org/10.1089/dna.1986.5.137
https://doi.org/10.1089/dna.1986.5.137
Publikováno v:
Nature. 248:675-678
THE replication of the RNA-containing bacteriophages has been found to involve specific replicases, partly coded by the phage genome (reviewed in refs 1 and 2). The replication proceeds by way of a partially double-stranded intermediate form, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e7cadff08e402d0fc87a95969beb3f
https://doi.org/10.1038/248675a0
https://doi.org/10.1038/248675a0
Autor:
B. Jenkins, John Spencer Emtage, Norman Henry Carey, William C.A. Tacon, Alan George Porter, G. H. Catlin
Publikováno v:
Nature. 283:171-174
A gene sequence for the fowl plague virus (FPV) haemagglutinin molecule has been inserted into a bacterial plasmid such that its transcription is under the control of a promoter derived from the tryptophan operon. Such plasmids direct the synthesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceef479bca08c07c1b545b321e636a0
https://doi.org/10.1038/283171a0
https://doi.org/10.1038/283171a0
Autor:
Norman Henry Carey, S.M. Doel, A. G. Stewart, T. Cartwright, Michael Houghton, J.R. Birch, M.A.W. Eaton, H. M. Lewis, John C. Smith, John Spencer Emtage, Alan George Porter, T.P. Patel
Publikováno v:
Nucleic acids research. 8(9)
From recently published data on the amino-terminal structures of human and mouse interferons, we have predicted and synthesised an oligonucleotide capable of priming specifically the reverse transcription of human fibroblast interferon mRNA present w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d1f3800b821563eae11bec6e5634ad
https://pubmed.ncbi.nlm.nih.gov/6159597
https://pubmed.ncbi.nlm.nih.gov/6159597