Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alan G. Ridgeway"'
Autor:
Sharon Wilton, Christopher Ward, Alan G. Ridgeway, Christina Karamboulas, Albert Swedani, Ashraf S. Al-Madhoun, Sophie Boisvenue, Ilona S. Skerjanc
Publikováno v:
Journal of Cell Science. 119:4305-4314
Class II histone deacetylases (HDAC4, HDAC5, HDAC7 and HDAC9) have been shown to interact with myocyte enhancer factors 2 (MEF2s) and play an important role in the repression of cardiac hypertrophy. We examined the role of HDACs during the differenti
Publikováno v:
Journal of Biological Chemistry. 279:23874-23881
Gli2 and Meox1 are transcription factors that are expressed in the developing somite and play roles in the commitment of cells to the skeletal muscle lineage. To further define their roles in regulating myogenesis, the function of wild type and domin
Publikováno v:
FEBS Letters. 456:399-402
The histidine-rich Ca2+ binding protein (HRC) resides in the sarcoplasmic reticulum of muscle and binds Ca2+. Since Ca2+ concentrations can regulate gene expression via calcineurin, the mouse homologue of HRC (mHRC) was isolated and characterized. mH
Publikováno v:
Journal of Biological Chemistry. 273:34904-34910
The Nkx2-5 homeodomain protein plays a key role in cardiomyogenesis. Ectopic expression in frog and zebrafish embryos results in an enlarged myocardium; however, expression of Nkx2-5 in fibroblasts was not able to trigger the development of beating c
Publikováno v:
Journal of cell science. 116(Pt 14)
Signaling through the p38 mitogen-activated protein kinases (MAPKs) is essential for cartilage formation in primary cultures of limb mesenchyme. Here we show that, concurrent with a decrease in chondrogenesis, inhibition of p38 in limb bud cultures d
Autor:
Alan G. Ridgeway, Ilona S. Skerjanc
Publikováno v:
The Journal of biological chemistry. 276(22)
Pax3 is a paired box transcription factor expressed during somitogenesis that has been implicated in initiating the expression of the myogenic regulatory factors during myogenesis. We find that Pax3 is necessary and sufficient to induce myogenesis in
Publikováno v:
The Journal of biological chemistry. 275(42)
The myogenic regulatory factors (MRFs), MyoD and myogenin, can induce myogenesis in a variety of cell lines but not efficiently in monolayer cultures of P19 embryonal carcinoma stem cells. Aggregation of cells expressing MRFs, termed P19[MRF] cells,