Correction: Determination of the presence of 5-methylcytosine in Paramecium tetraurelia.

Autor: Aditi Singh, Adrienne Vancura, Rafal K Woycicki, Daniel J Hogan, Alan G Hendrick, Mariusz Nowacki

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0209707 (2018)

[This corrects the article DOI: 10.1371/journal.pone.0206667.].

Externí odkaz: https://doaj.org/article/4520f2b883b3475891fa81bfb205b3d9

METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis

Autor: Pedro Rebelo-Guiomar, Aaron R. D’Souza, Lindsey Van Haute, Christopher A. Powell, Byron Andrews, Michael E. Harbour, Ian M. Fearnley, Michal Minczuk, Alan G. Hendrick, Shujing Ding

Publikováno v: Nucleic Acids Research

Post-transcriptional RNA modifications, the epitranscriptome, play important roles in modulating the functions of RNA species. Modifications of rRNA are key for ribosome production and function. Identification and characterization of enzymes involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a61220b77c7f607cc3873159b6f179c
https://doi.org/10.1093/nar/gkz735

Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans

Autor: Eric A. Miska, Alan G Hendrick, Fabian Braukmann, Isabela Cunha Navarro, David Jordan, Jonathan Price, Alper Akay, Francesca Tuorto, Annika Kotter, Carine Legrand, Mark Helm, Frank Lyko

Publikováno v: The EMBO Journal
EMBO journal
40 (2021). doi:10.15252/embj.2020105496
info:cnr-pdr/source/autori:Navarro I.C.; Tuorto F.; Jordan D.; Legrand C.; Price J.; Braukmann F.; Hendrick A.G.; Akay A.; Kotter A.; Helm M.; Lyko F.; Miska E.A./titolo:Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans/doi:10.15252%2Fembj.2020105496/rivista:EMBO journal (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:40

Methylation of carbon‐5 of cytosines (m5C) is a post‐transcriptional nucleotide modification of RNA found in all kingdoms of life. While individual m5C‐methyltransferases have been studied, the impact of the global cytosine‐5 methylome on dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2318249ee37e54124e3f22cc3d600a4c
http://europepmc.org/articles/PMC7957426

Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6)

Autor: Jennifer Turney, Henriëtte M. G. Willems, Philip J. Mitchell, Vivienne Allen, Alan G. Hendrick, Takashi Ito, Jenny Reeves, Susanne Wright, Ilka Müller, Richard J. Davenport, Richard Bazin, Stephen Wilkinson, Philip Leonard, Helen Heffron, Steve Irving

Publikováno v: Journal of Medicinal Chemistry. 59:8094-8102

Fatty acid binding protein 6 (FABP6) is a potential drug discovery target, which, if inhibited, may have a therapeutic benefit for the treatment of diabetes. Currently, there are no published inhibitors of FABP6, and with the target believed to be am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb461ea8115897027e5a13fb8162307c
https://doi.org/10.1021/acs.jmedchem.6b00869

Determination of the presence of 5-methylcytosine in Paramecium tetraurelia

Autor: Mariusz Nowacki, Alan G. Hendrick, Rafal Woycicki, Daniel J. Hogan, Aditi Singh, Adrienne Vancura

Publikováno v: PLOS ONE
PLoS ONE, Vol 13, Iss 10, p e0206667 (2018)
Singh, Aditi; Vancura, Adrienne; Woycicki, Rafal K.; Hogan, Daniel J; Hendrick, Alan G; Nowacki, Mariusz (2018). Determination of the presence of 5-methylcytosine in Paramecium tetraurelia. PLoS ONE, 13(10), e0206667. Public Library of Science 10.1371/journal.pone.0206667
PLoS ONE

5-methylcytosine DNA methylation regulates gene expression and developmental programming in a broad range of eukaryotes. However, its presence and potential roles in ciliates, complex single-celled eukaryotes with germline-somatic genome specializati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0703f864bf84c4165dff988a5d06a9