Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alan G. Fast"'
Autor:
Shawn W. Jones, Alan G. Fast, Ellinor D. Carlson, Carrissa A. Wiedel, Jennifer Au, Maciek R. Antoniewicz, Eleftherios T. Papoutsakis, Bryan P. Tracy
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Microbial fermentation yield is limited by CO2 loss in glycolysis. Here, the authors engineered Clostridium ljungdahlii for the anaerobic, non-photosynthetic mixotrophy production of acetone, increasing carbon product yield while reducing CO2emission
Externí odkaz:
https://doaj.org/article/2bf5559be7cc409bb433d82cf7f25ebf
Autor:
Maciek R. Antoniewicz, Bryan P. Tracy, Eleftherios T. Papoutsakis, Jennifer Au, Alan G. Fast, Carrissa A. Wiedel, Ellinor D. Carlson, Shawn W. Jones
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications
Nature Communications
Maximizing the conversion of biogenic carbon feedstocks into chemicals and fuels is essential for fermentation processes as feedstock costs and processing is commonly the greatest operating expense. Unfortunately, for most fermentations, over one-thi
Publikováno v:
Metabolic engineering. 50
Clostridium organisms are of major importance in the development of technologies to produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass-derived carbohydrates, as well as waste gases, waste materials, and C1 co
Publikováno v:
Applied and Environmental Microbiology. 84
Engineering the Wood-Ljungdahl pathway (WLP) in the established industrial organism Clostridium acetobutylicum would allow for the conversion of carbohydrates into butanol, acetone, and other metabolites at higher yields than are currently possible,
Autor:
Nicholas R. Sandoval, Robert Kyle Bennett, Eleftherios T. Papoutsakis, Alan G. Fast, William Brian Whitaker
Publikováno v:
Current Opinion in Biotechnology. 33:165-175
Synthetic methylotrophy is the development of non-native methylotrophs that can utilize methane and methanol as sole carbon and energy sources or as co-substrates with carbohydrates to produce metabolites as biofuels and chemicals. The availability o
Publikováno v:
Applied and Environmental Microbiology. 79:7210-7219
Reactive oxygen species are generated by redox reactions and the Fenton reaction of H 2 O 2 and iron that generates the hydroxyl radical that causes severe DNA, protein, and lipid damage. We screened Escherichia coli genomic libraries to identify a f
Publikováno v:
Biomaterials. 34:5431-5438
Gene delivery from tissue engineering scaffolds provides the opportunity to control the microenvironment by inducing expression of regenerative factors. Hydroxyapatite (HAp) nanoparticles can bind lentivirus, and we investigated the incorporation of
Publikováno v:
Applied and Environmental Microbiology. 78:8112-8121
Isolation of Clostridium mutants based on gene replacement via allelic exchange remains a major limitation for this important genus. Use of a heterologous counterselection marker can facilitate the identification of the generally rare allelic exchang
Publikováno v:
Current Opinion in Chemical Engineering. 1:380-395
An increasing focus on environmental sustainability has led to an ongoing global effort to better understand and engineer platform organisms that economically convert CO2 and other waste gases into useful biofuels and chemicals. Using stoichiometric
Publikováno v:
Current opinion in biotechnology. 33
Mass yields of biofuels and chemicals from sugar fermentations are limited by the decarboxylation reactions involved in Embden-Meyerhof-Parnas (EMP) glycolysis. This paper reviews one route to recapture evolved CO2 using the Wood-Ljungdahl carbon fix