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of 3
pro vyhledávání: '"Alan G. F. Worsley"'
Autor:
Naoto Ishii, Georgia Perona-Wright, Alan G. F. Worsley, Stephen J. Jenkins, Andrew S. MacDonald
Publikováno v:
The Journal of Immunology. 179:3515-3523
Costimulatory cross-talk can occur at multiple cellular levels to potentiate expansion and polarization of Th responses. Although OX40L ligand (OX40L) is thought to play a key role in Th2 development, the critical cellular source of this molecule has
Autor:
Nik M. Morton, Margaret Wilde, Val Lyons, Gretchen D. Darlington, Alan G. F. Worsley, Charlotte Bruley, Jonathan R. Seckl, Karen E. Chapman
Publikováno v:
Endocrinology. 147:2879-2885
11Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) increases intracellular glucocorticoid action by converting inactive to active glucocorticoids (cortisol, corticosterone) within cells. It is highly expressed in glucocorticoid target tissues i
Autor:
Alan G. F. Worsley, Emma Slack, Andrew S. MacDonald, Salomé LeibundGut-Landmann, Holger Gerhardt, Li-Kun Phng, Caetano Reis e Sousa
Publikováno v:
European journal of immunology. 38(4)
We have addressed the hypothesis that Notch ligands play a decisive role in determining the ability of antigen-presenting cells to influence T cell polarization. Dendritic cells displayed distinct expression profiles of Delta and Jagged ligands for N