Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alan F. Flint"'
Publikováno v:
Journal of Histochemistry & Cytochemistry. 53:861-873
Muscle side population (SP) cells have demonstrated hematopoietic and myogenic activities in vivo upon intravenous (IV) injection into lethally irradiated mdx mice. In contrast, muscle main population (MP) cells were unable to rescue the bone marrow
Autor:
Philippe Leboulch, François Rivier, Emanuela Gussoni, Kristina R. Muskiewicz, Ozan Alkan, Alan F. Flint, Paul D. Allen
Publikováno v:
Journal of Cell Science. 117:1979-1988
The multipotent nature of skeletal muscle-derived side population cells is demonstrated by their myogenic and hematopoietic potential in vivo. However, whether muscle side population cells are derived from the bone marrow is unclear. To study the lon
Autor:
Gary A. Silverman, Alan F. Flint, Marc Lalande, Ger van den Engh, Stephanie M. Hui, Allison J. Bartuski, Arabella Smith, Barbara Trask
Publikováno v:
Genomics. 26:364-371
Bivariate fluorescence-activated sorting is a method for obtaining relatively pure fractions of chromosomal DNA. Unfortunately, the yields (0.25 microgram/day) frequently limit the types of molecular analysis that can be performed. The polymerase cha
Publikováno v:
American Journal of Obstetrics and Gynecology. 170:202-206
Objective: We studied transferrin receptor (CD71) expression in peripheral blood mononuclear cells from healthy pregnant women, to determine if a relationship existed between gestational age and circulating CD71 + mononuclear cells. Study Design: Cel
Autor:
Kyoko Hida, Cynthia C. Morton, Dhara N. Amin, Dipak Panigrahy, Yasuhiro Hida, Michael Klagsbrun, Alan F. Flint
Publikováno v:
Cancer research. 64(22)
Tumor angiogenesis is necessary for solid tumor progression and metastasis. Tumor blood vessels have been shown to differ from normal counterparts, for example, by changes in morphology. An important concept in tumor angiogenesis is that tumor endoth
Publikováno v:
Blood. 103(4)
Infantile hemangioma is an endothelial tumor that grows rapidly after birth but slowly regresses during early childhood. Initial proliferation of hemangioma is characterized by clonal expansion of endothelial cells (ECs) and neovascularization. Here,
Autor:
Louis M. Kunkel, Elizabeth A. Buzney, Mohamed K. Khan, Corinne D. Strickland, Alan F. Flint, Emanuela Gussoni, Richard C. Mulligan, Yuko Soneoka
Publikováno v:
Nature. 401(6751)
The development of cell or gene therapies for diseases involving cells that are widely distributed throughout the body has been severely hampered by the inability to achieve the disseminated delivery of cells or genes to the affected tissues or organ
Autor:
Ossie H. Geifman, Melissa C. Yih, Diana W. Bianchi, Gretchen K. Zickwolf, John M. Williams, Marlena S. Erikson, Alan F. Flint
Publikováno v:
Prenatal diagnosis. 13(4)
Fetal nucleated erythrocytes (NRBC) in maternal blood are a non-invasive source of fetal DNA for prenatal genetic screening. We compared the effectiveness of three monoclonal antibodies for the separation of fetal cells from maternal blood by flow so
Publikováno v:
Prenatal diagnosis. 11(8)
Maternal venous blood samples, obtained from six pregnant women, were used as a source of fetal nucleated erythrocytes (NRBC). Fetal cell enrichment was potentiated by flow sorting with the monoclonal antibodies TfR, Leu-4, and Leu-M3. Single copy Y
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(9)
Fetal nucleated cells within maternal blood represent a potential source of fetal genes obtainable by venipuncture. We used monoclonal antibody against the transferrin receptor (TfR) to identify nucleated erythrocytes in the peripheral blood of pregn