Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Alan E. Nahum"'
Theoretical investigation of the impact of different timing schemes in hypofractionated radiotherapy
Autor:
Alan E. Nahum, P. Stavrev, Dimitar Penev, Nadejda Stavreva, Ruggero Ruggieri, Pavlin Tsonev, Dobromir S. Pressyanov
Publikováno v:
Medical Physics. 48:4085-4098
PURPOSE This study compares the effectiveness of three fractionation schemes of equal fraction size, comprising five fractions of SBRT over 5 days, 10 days, or 15 days, respectively. METHOD This comparative study is based on two tumor-control-probabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5c9828ab54cf85521feafa529fac1d
https://doi.org/10.1002/mp.14908
https://doi.org/10.1002/mp.14908
Publikováno v:
Physics in Medicine & Biology. 68:09NT01
Objective. An artifact in the electron fluence, differential in energy, Φ E , computed by the EGSnrc Monte-Carlo user-code FLURZnrc, was identified and a methodology has been developed to eliminate it. This artifact manifests itself as an ‘unphysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e541a8219e241063455842a8e557c6
https://doi.org/10.1088/1361-6560/acc30c
https://doi.org/10.1088/1361-6560/acc30c
Autor:
Dobromir S. Pressyanov, Filippo Alongi, Boriana Genova, P. Stavrev, Nadejda Stavreva, Alan E. Nahum, Ruggero Ruggieri
Publikováno v:
Cancers
Volume 13
Issue 19
Cancers, Vol 13, Iss 4899, p 4899 (2021)
Volume 13
Issue 19
Cancers, Vol 13, Iss 4899, p 4899 (2021)
Simple Summary Reported clinical data on high dose rate mono brachytherapy of prostate cancer carried out using two different treatment regimens are analyzed in this study. The analysis is based on a mechanistic tumor control probability model, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d185eae7a6688e3c1873b7d0fb00642b
Autor:
Danny Y. Song, Alan E. Nahum, Sean P. Collins, Aaron D. Falchook, Jimm Grimm, Ronald C. Chen, Ellen Yorke, Issam El Naqa, Trevor J. Royce, Andrew Jackson, Nathan C. Sheets, George X. Ding, Donald B. Fuller, Kyle Wang, Panayiotis Mavroidis
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Dose escalation improves localized prostate cancer disease control, and moderately hypofractionated external beam radiation is noninferior to conventional fractionation. The evolving treatment approach of ultrahypofractionation with stereotac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c22b00ea819a5dedbd2654e82dc1ed
https://pubmed.ncbi.nlm.nih.gov/32900561
https://pubmed.ncbi.nlm.nih.gov/32900561
Publikováno v:
Clinical Oncology. 29:6-14
Aims For patients with high-risk, locally bulky prostate cancer, an intra-prostatic boost to tumour volumes (dose-painting) offers a risk-adapted dose escalation. We evaluated the feasibility of hypofractionated dose-painting radiotherapy and the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be5f6954f75b73a6460f682954f7bdd
https://doi.org/10.1016/j.clon.2016.09.009
https://doi.org/10.1016/j.clon.2016.09.009
Autor:
Anna Balabanova, Ruggero Ruggieri, Dobromir S. Pressyanov, Alan E. Nahum, P. Stavrev, Nadejda Stavreva
Publikováno v:
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 63
Purpose To investigate the impact of a variable inter-individual spread in the tumour cell radiosensitivity and repopulation rate on the tumour control probability (TCP). Methods The radiosensitivity parameters and the repopulation rate are presumed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e09dc94bec18c72df508eff5d75aee6
https://pubmed.ncbi.nlm.nih.gov/31221413
https://pubmed.ncbi.nlm.nih.gov/31221413
Autor:
Alan E. Nahum, Giovanni Borasi
Publikováno v:
Physica Medica. 32:1175-1179
Purpose In recent years, the reaction-diffusion (Fisher-Kolmogorov) equation has received much attention from the oncology research community due to its ability to describe the infiltrating nature of glioblastoma multiforme and its extraordinary resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bafc5429721fcff6c14a7775aa30acd
https://doi.org/10.1016/j.ejmp.2016.08.020
https://doi.org/10.1016/j.ejmp.2016.08.020
Publikováno v:
Clinical Oncology. 28:165-170
Aims To describe the treatment of 11 patients with radiobiologically guided dose-painting radiotherapy and report on toxicity. Materials and methods Boost volumes were identified with functional magnetic resonance imaging scans in 11 patients with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d323a62f8ba7bbd94f323917802911b
https://doi.org/10.1016/j.clon.2015.09.006
https://doi.org/10.1016/j.clon.2015.09.006
Publikováno v:
Physics in Medicine & Biology. 65:175012
Small-field dosimetry is central to the planning and delivery of radiotherapy to patients with cancer. Small-field dosimetry is beset by complex issues, such as loss of charged-particle equilibrium (CPE), source occlusion and electron scattering effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f14b39e93fdaa3afeb3b8d1a89ab2a2
https://doi.org/10.1088/1361-6560/ab98d1
https://doi.org/10.1088/1361-6560/ab98d1
Autor:
Ruggero Ruggieri, Alan E. Nahum, P. Stavrev, Nadejda Stavreva, Dobromir S. Pressyanov, Dimitar Penev
Publikováno v:
Physics in medicine and biology. 63(20)
The aim of the work is to investigate the impact of radiation-independent (natural or spontaneous) tumor cell death on tumor control probability (TCP) during and following fractionated external-beam radiotherapy employing both analytical and numerica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b89a81e96f3e9f64451ff026e0e7c
https://pubmed.ncbi.nlm.nih.gov/30204124
https://pubmed.ncbi.nlm.nih.gov/30204124