Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Alan E. Berger"'
Autor:
Shuming Chen, Tracee L. McMiller, Abha Soni, Farah Succaria, John-William Sidhom, Laura C. Cappelli, Livia A. Casciola-Rosen, Isaac R. Morales, Preethi Sankaran, Alan E. Berger, Julie Stein Deutsch, Qingfeng C. Zhu, Robert A. Anders, Jody E. Hooper, Drew M. Pardoll, Evan J. Lipson, Janis M. Taube, Suzanne L. Topalian
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Tumor regression following immune checkpoint blockade (ICB) is often associated with immune-related adverse events (irAEs), marked by inflammation in non-cancerous tissues. This study was undertaken to investigate the functional r
Externí odkaz:
https://doaj.org/article/44edc95deb6444eabbd3e50a4991237d
Autor:
Amy S. Duffield, Maria Libera Ascierto, Robert A. Anders, Janis M. Taube, Alan K. Meeker, Shuming Chen, Tracee L. McMiller, Neil A. Phillips, Haiying Xu, Aleksandra Ogurtsova, Alan E. Berger, Drew M. Pardoll, Suzanne L. Topalian, Richard F. Ambinder
Publikováno v:
Blood Advances, Vol 1, Iss 17, Pp 1324-1334 (2017)
Abstract: Classical Hodgkin lymphoma (CHL) is a neoplasm characterized by robust inflammatory infiltrates and heightened expression of the immunosuppressive PD-1/PD-L1 pathway. Although anti-PD-1 therapy can be effective in >60% of patients with refr
Externí odkaz:
https://doaj.org/article/a34c1ebc512840c184df62031f0ea438
Autor:
Bryan J. McCranor, Jacqueline M. Langdon, Olivier D. Prince, Laurette K. Femnou, Alan E. Berger, Chris Cheadle, Curt I. Civin, Airie Kim, Seth Rivera, Tomas Ganz, Sophie Vaulont, Qian-Li Xue, Jeremy D. Walston, Cindy N. Roy
Publikováno v:
Haematologica, Vol 98, Iss 10 (2013)
Anemia is common in older adults and associated with adverse health outcomes in epidemiological studies. A thorough understanding of the complex pathophysiological mechanisms driving anemia in the elderly is lacking; but inflammation, iron restrictio
Externí odkaz:
https://doaj.org/article/2a71572794b94f96a966b13482b6d5d5
Autor:
Olivier D. Prince, Jacqueline M. Langdon, Andrew J. Layman, Ian C. Prince, Miguel Sabogal, Howard H. Mak, Alan E. Berger, Chris Cheadle, Francis J. Chrest, Qilu Yu, Nancy C. Andrews, Qian-Li Xue, Curt I. Civin, Jeremy D. Walston, Cindy N. Roy
Publikováno v:
Haematologica, Vol 97, Iss 11 (2012)
Background We and others have shown previously that over-expression of hepcidin antimicrobial peptide, independently of inflammation, induces several features of anemia of inflammation and chronic disease, including hypoferremia, sequestration of iro
Externí odkaz:
https://doaj.org/article/3a08fab1eb3940f9a378f57c43dd5c90
Autor:
Suzanne L. Topalian, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Leslie Cope, Chris Cheadle, Jinshui Fan, Theresa S. Pritchard, Haiying Xu, George J. Netto, Robert A. Anders, Ludmila Danilova, Alan E. Berger, Tracee L. McMiller, Maria Libera Ascierto
Supplementary Table S1: PD-L1+ RCC specimens used in this study. Supplementary Table S2: Genes differentially expressed in RCC based on whole genome microarray analysis, in patients responding or not to anti-PD-1 therapy (234 probe sets corresponding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d400de265cdb154eb97ff7a1eaf107d6
https://doi.org/10.1158/2326-6066.22537255.v1
https://doi.org/10.1158/2326-6066.22537255.v1
Autor:
Suzanne L. Topalian, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Leslie Cope, Chris Cheadle, Jinshui Fan, Theresa S. Pritchard, Haiying Xu, George J. Netto, Robert A. Anders, Ludmila Danilova, Alan E. Berger, Tracee L. McMiller, Maria Libera Ascierto
Figure S1: Extraction of paraffin-embedded PD-L1+ RCC tissues for RNA isolation. Figure S2: Molecules previously found to be up-regulated in PD-L1+ vs. PD-L1(-) melanomas are not differentially expressed in PD-L1+ RCCs from patients with divergent cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beca862ceb9e1c6e6ef19792422d59b9
https://doi.org/10.1158/2326-6066.22537261.v1
https://doi.org/10.1158/2326-6066.22537261.v1
Autor:
Suzanne L. Topalian, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Leslie Cope, Chris Cheadle, Jinshui Fan, Theresa S. Pritchard, Haiying Xu, George J. Netto, Robert A. Anders, Ludmila Danilova, Alan E. Berger, Tracee L. McMiller, Maria Libera Ascierto
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267b06e4562b217ebd89d0b683096ba7
https://doi.org/10.1158/2326-6066.22537258.v1
https://doi.org/10.1158/2326-6066.22537258.v1
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63303e1e95df28f9c3ec11824d417863
https://doi.org/10.1158/1078-0432.22457678
https://doi.org/10.1158/1078-0432.22457678
Autor:
Suzanne L. Topalian, Christine A. Iacobuzio-Donahue, David B. Solit, Barry S. Taylor, Drew M. Pardoll, Ralph H. Hruban, Leslie Cope, Timothy A. Chan, Nadeem Riaz, Vladimir Makarov, Alexander Favorov, Zachary A. Kohutek, Tricia R. Cottrell, Genevieve J. Kaunitz, Jinshui Fan, Alan E. Berger, Tracee L. McMiller, Janis M. Taube, Evan J. Lipson, Alvin Makohon-Moore, Maria L. Ascierto
140 Illumina probes corresponding to138 unique genes differentially expressed in regressing (R) vs. progressing (P) cutaneous metastases based on whole genome microarray analysis (fold change magnitude {greater than or equal to}1.7, p value {less tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22226b728fa308c97786f5115cacc5d
https://doi.org/10.1158/1078-0432.22463553.v1
https://doi.org/10.1158/1078-0432.22463553.v1
Autor:
Suzanne L. Topalian, Drew M. Pardoll, Alan E. Berger, Chris Cheadle, Jinshui Fan, Alan K. Meeker, Haiying Xu, Theresa S. Pritchard, January T. Salas, Shuming Chen, Tracee L. McMiller, Geoffrey D. Young, Janis M. Taube
Supplementary Table S4: DAVID clustering of 1660 Illumina probes up-regulated at least 2-fold in PD-L1+ melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d20ea9320f7573c2c11ebbbfac0a2b
https://doi.org/10.1158/1078-0432.22457681.v1
https://doi.org/10.1158/1078-0432.22457681.v1