Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alan E Lopez-Hernandez"'
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 3, Pp 2372-2383 (2021)
COVID-19 is increasingly affecting human health and global economy. Understanding the fundamental mechanisms of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is highly demanded to develop treatments for COVID-19. SARS-CoV and SARS-CoV-
Externí odkaz:
https://doaj.org/article/5c8c35bf14524c5d80b80231ce4a25e8
Autor:
Wenhan Guo, Shengjie Sun, Jason E. Sanchez, Alan E. Lopez-Hernandez, Tolulope A. Ale, Jiawei Chen, Tanjina Afrin, Weihong Qiu, Yixin Xie, Lin Li
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4305-4314 (2022)
Kinesins are microtubule-based motor proteins that play important roles ranging from intracellular transport to cell division. Human Kinesin-5 (Eg5) is essential for mitotic spindle assembly during cell division. By combining molecular dynamics (MD)
Externí odkaz:
https://doaj.org/article/c8a71c550e024d2294df30b9a7b2efa3
Autor:
Shengjie Sun, Georgialina Rodriguez, Yixin Xie, Wenhan Guo, Alan E. Lopez Hernandez, Jason E. Sanchez, Robert Arthur Kirken, Lin Li
Publikováno v:
Life, Vol 13, Iss 4, p 981 (2023)
Janus Kinase 3 (JAK3) plays a key role in the development, proliferation, and differentiation of various immune cells. It regulates gene expression by phosphorylation of Signal Transducers and Activators of Transcriptions (STATs) via the JAK/STAT pat
Externí odkaz:
https://doaj.org/article/2fbecfce9ae2446681b571d497480034
Publikováno v:
Journal of Computational Biophysics and Chemistry. 20:201-207
Dengue virus causes serious diseases and deaths in the world. Understanding the fundamental mechanisms of dengue virus is highly demanded to develop treatments for dengue virus caused diseases. Here, we present a computational work which focused on t
Publikováno v:
Mathematical biosciences and engineering : MBE
Mathematical Biosciences and Engineering, Vol 18, Iss 3, Pp 2372-2383 (2021)
Mathematical Biosciences and Engineering, Vol 18, Iss 3, Pp 2372-2383 (2021)
COVID-19 is increasingly affecting human health and global economy. Understanding the fundamental mechanisms of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is highly demanded to develop treatments for COVID-19. SARS-CoV and SARS-CoV-
Publikováno v:
Journal of Chemical Theory and Computation
SARS-CoV-2 that caused COVID-19 has spread since the end of 2019. Its major effects resulted in over four million deaths around the whole world by August 2021. Therefore, understanding virulence mechanisms is important to prevent future outbreaks and
Autor:
Jianjun Sun, Yuejiao Xian, Lin Li, Yixin Xie, Brenda Y Juarez, Alan E Lopez-Hernandez, Chitra B. Karki, Shengjie Sun, Jun Wang
Publikováno v:
J Theor Comput Chem
One quarter of the world’s population are infected by Mycobacterium tuberculosis (Mtb), which is a leading death-causing bacterial pathogen. Recent evidence has demonstrated that two virulence factors, ESAT-6 and CFP-10, play crucial roles in Mtb