Výsledky vyhledávání - "Alan E Lomax"

Akademický článek

Ion channel expression in the developing enteric nervous system.

Autor: Caroline S Hirst, Jaime P P Foong, Lincon A Stamp, Emily Fegan, Stephan Dent, Edward C Cooper, Alan E Lomax, Colin R Anderson, Joel C Bornstein, Heather M Young, Sonja J McKeown

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0123436 (2015)

The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemist

Externí odkaz: https://doaj.org/article/18e2ce8bc6214ba3a13c98a8aa9cae69

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Akademický článek

The emerging roles of bacterial proteases in intestinal diseases

Autor: Alberto Caminero, Mabel Guzman, Josie Libertucci, Alan E. Lomax

Publikováno v: Gut Microbes, Vol 15, Iss 1 (2023)

ABSTRACTProteases are an evolutionarily conserved family of enzymes that degrade peptide bonds and have been implicated in several common gastrointestinal (GI) diseases. Although luminal proteolytic activity is important for maintenance of homeostasi

Externí odkaz: https://doaj.org/article/b99e743423ca4008847ce20635ddae3c

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Akademický článek

Role of the endocannabinoid system in the pathophysiology of endometriosis and therapeutic implications

Autor: Harshavardhan Lingegowda, Bailey J. Williams, Katherine G. Spiess, Danielle J. Sisnett, Alan E. Lomax, Madhuri Koti, Chandrakant Tayade

Publikováno v: Journal of Cannabis Research, Vol 4, Iss 1, Pp 1-13 (2022)

Abstract Endometriosis patients experience debilitating chronic pain, and the first-line treatment is ineffective at managing symptoms. Although surgical removal of the lesions provides temporary relief, more than 50% of the patients experience disea

Externí odkaz: https://doaj.org/article/3dab86a06c4b4337978ae80fecfc786b

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Akademický článek

Synthetic Cannabinoid Agonist WIN 55212-2 Targets Proliferation, Angiogenesis, and Apoptosis via MAPK/AKT Signaling in Human Endometriotic Cell Lines and a Murine Model of Endometriosis

Autor: Harshavardhan Lingegowda, Jessica E. Miller, Ryan M. Marks, Lindsey K. Symons, Taylor Alward, Alan E. Lomax, Madhuri Koti, Chandrakant Tayade

Publikováno v: Frontiers in Reproductive Health, Vol 3 (2021)

Endometriosis (EM) is characterized by the growth of endometrium-like tissue outside the uterus, leading to chronic inflammation and pelvic pain. Lesion proliferation, vascularization, and associated inflammation are the hallmark features of EM lesio

Externí odkaz: https://doaj.org/article/14b223a4f302427d96f8b58163612051

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