Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alan DenAdel"'
Publikováno v:
WIREs Computational Statistics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4503b5550c2bd14a329550e5e5505f9
https://doi.org/10.1002/wics.1617
https://doi.org/10.1002/wics.1617
Epistasis, commonly defined as the interaction between genetic loci, is known to play an important role in the phenotypic variation of complex traits. As a result, many statistical methods have been developed to identify genetic variants that are inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f32c1fccb7c24add894b04d972530b
https://doi.org/10.1101/2022.11.30.518547
https://doi.org/10.1101/2022.11.30.518547
Autor:
Srivatsan Raghavan, Peter S. Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Kristen E. Lowder, Jennyfer Galvez-Reyes, Radha L. Kalekar, Nolawit Mulugeta, Kevin S. Kapner, Manisha S. Raghavan, Ashir A. Borah, Nuo Liu, Sara A. Väyrynen, Andressa Dias Costa, Raymond W.S. Ng, Junning Wang, Emma K. Hill, Dorisanne Y. Ragon, Lauren K. Brais, Alex M. Jaeger, Liam F. Spurr, Yvonne Y. Li, Andrew D. Cherniack, Matthew A. Booker, Elizabeth F. Cohen, Michael Y. Tolstorukov, Isaac Wakiro, Asaf Rotem, Bruce E. Johnson, James M. McFarland, Ewa T. Sicinska, Tyler E. Jacks, Ryan J. Sullivan, Geoffrey I. Shapiro, Thomas E. Clancy, Kimberly Perez, Douglas A. Rubinson, Kimmie Ng, James M. Cleary, Lorin Crawford, Scott R. Manalis, Jonathan A. Nowak, Brian M. Wolpin, William C. Hahn, Andrew J. Aguirre, Alex K. Shalek
Publikováno v:
Cell. 184:6119-6137.e26
Prognostically relevant RNA expression states exist in pancreatic ductal adenocarcinoma (PDAC), but our understanding of their drivers, stability, and relationship to therapeutic response is limited. To examine these attributes systematically, we pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd273b2629d5e67001a6dfb5f7f3d83
https://doi.org/10.1016/j.cell.2021.11.017
https://doi.org/10.1016/j.cell.2021.11.017
Autor:
Nolawit Mulugeta, Lauren K. Brais, James M. Cleary, Kristen E. Lowder, Brian M. Wolpin, Jonathan A. Nowak, Radha L. Kalekar, Emma Reilly, Andrew J. Aguirre, Alex K. Shalek, Junning Wang, William C. Hahn, Alan DenAdel, Srivatsan Raghavan, Manisha S. Raghavan, Jennyfer Galvez-Reyes, Dorisanne Y. Ragon, Alex M. Jaeger, Peter S. Winter, Lorin Crawford, Hannah Williams, Sara A. Väyrynen, Ashir A. Borah, Andressa Dias Costa, Andrew W. Navia
Publikováno v:
Cancer Research. 80:PO-058
Metastatic pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy with few therapeutic options. Tumor transcriptional state is a strong predictor of clinical outcome in PDAC, with two primary cell states, basal-like and classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26052cdb17a88335df51ba80b58b2c9e
https://doi.org/10.1158/1538-7445.panca20-po-058
https://doi.org/10.1158/1538-7445.panca20-po-058
Autor:
Alex K. Shalek, Junning Wang, Emma Reilly, Lorin Crawford, Radha L. Kalekar, Brian M. Wolpin, Andrew W. Navia, William C. Hahn, Nolawit Mulugeta, Lauren K. Brais, James M. McFarland, Hannah Williams, Jonathan A. Nowak, Ashir A. Borah, Jennyfer Galvez-Reyes, Srivatsan Raghavan, Alan DenAdel, Peter S. Winter, James M. Cleary, Kristen E. Lowder, Andrew J. Aguirre, Manisha S. Raghavan
Publikováno v:
Cancer Research. 80:PR02-PR02
The majority of patients with pancreatic ductal adenocarcinoma (PDAC) present with metastatic disease at diagnosis and have median survival times of less than 12 months. Recent studies have demonstrated that PDAC tumors with distinct transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e291d8c8b5f5436b4f987b7ec6718956
https://doi.org/10.1158/1538-7445.camodels2020-pr02
https://doi.org/10.1158/1538-7445.camodels2020-pr02