Výsledky vyhledávání - "Alan D. Hendricker"

Extractables Characterization for Five Materials of Construction Representative of Packaging Systems Used for Parenteral and Ophthalmic Drug Products

Autor: Daniel L. Norwood, Diane Paskiet, Arthur J. Shaw, Edward J. Smith, Desmond G. Hunt, Dennis Jenke, Thomas Egert, Michael Ruberto, Michael P. Lynch, James Castner, Christopher Houston, Frank Holcomb, Kumudini Nicholas, Tom Feinberg, Alan D. Hendricker

Publikováno v: PDA Journal of Pharmaceutical Science and Technology. 67:448-511

Polymeric and elastomeric materials are commonly encountered in medical devices and packaging systems used to manufacture, store, deliver, and/or administer drug products. Characterizing extractables from such materials is a necessary step in establi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2bf64ea03f9b8e73c853acdb050d7e
https://doi.org/10.5731/pdajpst.2013.00933

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Rapid chemotaxonomy of pathogenic bacteria using in situ thermal hydrolysis and methylation as a sample preparation step coupled with a field–portable membrane-inlet quadrupole ion trap mass spectrometer

Autor: Ted L. Hadfield, Franco Basile, Christy Abbas-Hawks, Kent J. Voorhees, Alan D. Hendricker

Publikováno v: International Journal of Mass Spectrometry. :331-342

A field-portable, pyrolysis membrane-inlet quadrupole ion trap mass spectrometer has been used to characterize four pathogenic bacteria ( Bacillus anthracis, Brucella melitensis, Yersinia pestis , and Francisella tularensis ). Moreover, a variety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b6a1690085d6367f29b1f4c6ca7d7a6
https://doi.org/10.1016/s1387-3806(98)14266-5

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Amino acid and oligopeptide analysis using Curie-point pyrolysis mass spectrometry with in-situ thermal hydrolysis and methylation: mechanistic considerations

Autor: Alan D. Hendricker, Kent J. Voorhees

Publikováno v: Journal of Analytical and Applied Pyrolysis. 48:17-33

In-situ thermal hydrolysis and methylation-mass spectrometry has been used to study amino acids and oligopeptides containing glycine and alanine. Using tetramethylammonium hydroxide (TMAH) during Curie-point pyrolysis, methylation occurred on groups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48c580a6c058aaebc5e46ef759fced2c
https://doi.org/10.1016/s0165-2370(98)00100-4

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A study of protein oxidative products using a pyrolysis-membrane inlet quadrupole ion trap mass spectrometer with air as the buffer gas

Autor: Alan D. Hendricker, Franco Basile, Kent J. Voorhees

Publikováno v: Journal of Analytical and Applied Pyrolysis. 46:65-82

Pyrolysis-membrane inlet mass spectrometry has been used to investigate the oxidative products of several peptides in an air buffered quadrupole ion trap mass spectrometer. Results indicate that ion-molecule reactions can occur with solvent species p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d32acc5ec95f5913e0f182239ad64c3
https://doi.org/10.1016/s0165-2370(98)00070-9

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The use of biomarker compounds for the identification of bacteria by pyrolysis-mass spectrometry

Autor: Ted L. Hadfield, Alan D. Hendricker, Michael B. Beverly, Kent J. Voorhees, Christy Abbas-Hawks, Franco Basile, Robert B. Cody

Publikováno v: Journal of Analytical and Applied Pyrolysis. :111-134

Several recent advances in using biomarkers for bacteria characterization are discussed. A study using Gram-positive and Gram-negative bacteria has been conducted to compare both gas chromatographic and mass spectrometric analyses of the separately i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7ec974f8a83f7a77821d13a17db1610
https://doi.org/10.1016/s0165-2370(97)00035-1

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An investigation into the Curie-point pyrolysis-mass spectrometry of glycyl dipeptides

Autor: Kent J. Voorhees, Alan D. Hendricker

Publikováno v: Journal of Analytical and Applied Pyrolysis. 36:51-70

Thirty-nine dipeptides with a fixed N- or C-terminal amino acid of glycine have been investigated by Curie-point pyrolysis-mass spectrometry. The non-fixed amino acid was varied among the 20 naturally occurring amino acids. Results indicate that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e41d2080c73c2c009ca42e92c18c5711
https://doi.org/10.1016/0165-2370(95)00920-5

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An investigation of the pyrolysis of oligopeptides by Curie-point pyrolysis—tandem mass spectrometry

Autor: Kent J. Voorhees, B. Murugaverl, Wenhui Zhang, Alan D. Hendricker

Publikováno v: Journal of Analytical and Applied Pyrolysis. 30:1-16

The mechanisms of the thermal fragmentation of oligopeptides (ranging from three to six amino acid residues) upon Curie-point pyrolysis—mass spectrometry have been investigated. The results support the formation of diketopiperazines (DKP) or cyclic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b5ab481c28f9d1d3da811656c5a62a5
https://doi.org/10.1016/0165-2370(94)00795-0

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Validation using sensitivity and target transform factor analyses of neuralnetwork models for classifying bacteriafrom mass spectra

Autor: Kent J. Voorhees, Peter de B. Harrington, Franco Basile, Alan D. Hendricker

Publikováno v: Journal of the American Society for Mass Spectrometry. (1):10-21

Temperature constrained cascade correlation networks (TCCCNs) are computational neural networks that configure their own architecture, train rapidly, and give reproducible prediction results. TCCCN classification models were built using the Latin-par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd55305685264776d3abc0aa7366d420

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