Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Alan D, Elbein"'
Publikováno v:
Journal of Biological Chemistry. 285:9803-9812
We show that Mycobacterium smegmatis has an enzyme catalyzing transfer of maltose from [14C]maltose 1-phosphate to glycogen. This enzyme was purified 90-fold from crude extracts and characterized. Maltose transfer required addition of an acceptor. Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb79e2aa137288d44249db870280dcd5
https://doi.org/10.1074/jbc.m109.033944
https://doi.org/10.1074/jbc.m109.033944
Autor:
Alan D. Elbein, J. D. Carroll, Naoki Asano, Vineetha Koroth Edavana, Y. T. Pan, Irena Pastuszak
Publikováno v:
FEBS Journal. 275:3408-3420
Trehalose (α,α-1,1-glucosyl-glucose) is essential for the growth of mycobacteria, and these organisms have three different pathways that can produce trehalose. One pathway involves the enzyme described in the present study, trehalose synthase (TreS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029c02675635b3ad9f1bf655e849bc4e
https://doi.org/10.1111/j.1742-4658.2008.06491.x
https://doi.org/10.1111/j.1742-4658.2008.06491.x
Publikováno v:
FEBS Journal. 274:1701-1714
Trehalose is a nonreducing disaccharide of glucose (α,α-1,1-glucosyl-glucose) that is essential for growth and survival of mycobacteria. These organisms have three different biosynthetic pathways to produce trehalose, and mutants devoid of all thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92a98ad5436c3ecd41beddb2a77c91c
https://doi.org/10.1111/j.1742-4658.2007.05715.x
https://doi.org/10.1111/j.1742-4658.2007.05715.x
Autor:
Yuan T. Pan, J. David Carroll, Alan D. Elbein, William J. Jourdian, Irena Pastuszak, Vineetha Koroth Edavana, Rick Edmondson
Publikováno v:
European Journal of Biochemistry. 271:4259-4269
Trehalose synthase (TreS) catalyzes the reversible interconversion of trehalose (glucosyl-alpha,alpha-1,1-glucose) and maltose (glucosyl-alpha1-4-glucose). TreS was purified from the cytosol of Mycobacterium smegmatis to give a single protein band on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63fe01bb37613de108b8daa2e8a1392
https://doi.org/10.1111/j.1432-1033.2004.04365.x
https://doi.org/10.1111/j.1432-1033.2004.04365.x
Autor:
Vineetha Koroth Edavana, Alan D. Elbein, Prajitha Thampi, Edathera C. Abraham, Irena Pastuszak, J. D. Carroll
Publikováno v:
Archives of Biochemistry and Biophysics. 426:250-257
Two open reading frames in the Mycobacterium tuberculosis genome, Rv3372 and Rv2006 , have about 25% sequence identity at the amino acid level to the trehalose-phosphate phosphatase (TPP) purified from Mycobacterium smegmatis. However, the protein pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00b783c98987a0ea48e9cac37e39f84
https://doi.org/10.1016/j.abb.2004.02.014
https://doi.org/10.1016/j.abb.2004.02.014
Publikováno v:
Neuropsychopharmacology. 24:267-277
We have previously demonstrated elevation of the extracellular signal-regulated kinase (ERK) pathway in the cerebellum from patients with schizophrenia, an illness that may involve dysfunction of the N-methyl-D-aspartate (NMDA) receptor. Since the NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ab16108bee2934932de1861b64239f
https://doi.org/10.1016/s0893-133x(00)00180-9
https://doi.org/10.1016/s0893-133x(00)00180-9
Autor:
Baitang Ning, Alan D. Elbein
Publikováno v:
European Journal of Biochemistry. 267:6866-6874
GDP-Man, the mannosyl donor for most Man-containing polymers is formed by the transfer of Man-1-P to GTP to form GDP-Man and PPi. This reaction is catalyzed by the widespread and essential enzyme, GDP-Man pyrophosphorylase (GMPP). The pig liver GMPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6183ac329e747ed6967a97bf380503
https://doi.org/10.1046/j.1432-1033.2000.01781.x
https://doi.org/10.1046/j.1432-1033.2000.01781.x
Autor:
Theron L. Hutton, Craig N. Karson, Svetlana V. Kyosseva, W. Sue T. Griffin, Robert E. Mrak, Alan D. Elbein, William Q. Sturner
Publikováno v:
Archives of General Psychiatry. 57:685-691
We investigated the levels of transcription factors associated with activation of the mitogen-activated protein (MAP) kinase pathway in schizophrenics using postmortem brain samples. These studies were done to determine whether our previous findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8740e167cd94a0cd852c31a5c6f37418
https://doi.org/10.1001/archpsyc.57.7.685
https://doi.org/10.1001/archpsyc.57.7.685
Autor:
Alan D. Elbein, Gary G. Hermanson, Eric R. Sjoberg, Catherine Ketchum, Richard R. Drake, Irena Pastuszak
Publikováno v:
Journal of Biological Chemistry. 273:30165-30174
The enzyme that catalyzes the formation of GDP-l-fucose from GTP and β-l-fucose-1-phosphate (i.e.GDP-β-l-fucose pyrophosphorylase, GFPP) was purified about 560-fold from the cytosolic fraction of pig kidney. At this stage, there were still a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a99ef3a2dffacc923476728bd7286b0
https://doi.org/10.1074/jbc.273.46.30165
https://doi.org/10.1074/jbc.273.46.30165
Autor:
Alan D. Elbein, Russell J. Molyneux
Publikováno v:
Iminosugars as Glycosidase Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b89aabe87e71f3bf756fc39616c6401
https://doi.org/10.1002/3527601740.ch11
https://doi.org/10.1002/3527601740.ch11