Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Alan Cox"'
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 140-148 (2023)
Micro RNAs (miRNAs) are short, non-coding RNAs with significant potential as diagnostic and prognostic biomarkers. However, a lack of reproducibility across studies has hindered their introduction into clinical settings. Inconsistencies between studi
Externí odkaz:
https://doaj.org/article/c7471af3245c40bd99ebd685a916a254
Autor:
Samantha L. Gerlach, James S. Metcalf, Rachael A. Dunlop, Sandra Anne Banack, Cheenou Her, Viswanathan V. Krishnan, Ulf Göransson, Sunithi Gunasekera, Blazej Slazak, Paul Alan Cox
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2216 (2024)
Glioblastoma (GBM) is the most aggressive cancer originating in the brain, but unfortunately combination treatments with resection, radiation, and chemotherapy are relatively ineffective. Therefore, novel methods of adjuvant therapy are critically ne
Externí odkaz:
https://doaj.org/article/f4fdaa1889434580889361de7e371890
Autor:
Susanna P. Garamszegi, Sandra Anne Banack, Linda L. Duque, James S. Metcalf, Elijah W. Stommel, Paul Alan Cox, David A. Davis
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 87-96 (2023)
Introduction: Cyanobacterial blooms produce toxins that may become aerosolized, increasing health risks through inhalation exposures. Health related effects on the lower respiratory tract caused by these toxins are becoming better understood. However
Externí odkaz:
https://doaj.org/article/2b14a4bd0187461c81a78f2378726314
Autor:
Melissa R. L. Whitaker, Sandra Anne Banack, Mark C. Mescher, Paul Alan Cox, Consuelo M. De Moraes
Publikováno v:
Frontiers in Ecology and Evolution, Vol 11 (2023)
Many herbivorous Lepidoptera accumulate plant toxins within their own tissues as a defensive strategy. Pioneering research in this area was conducted by Miriam Rothschild and Deane Bowers, who showed that the cycad-feeding butterfly Eumaeus atala seq
Externí odkaz:
https://doaj.org/article/b5ee50a974b04c4ea8e0c2a02ab66982
Publikováno v:
Toxins, Vol 15, Iss 11, p 659 (2023)
The Great Salt Lake in Utah is the largest saline lake in the Western hemisphere and one of the largest terminal lakes in the world. Situated at the eastern edge of the Great Basin, it is a remnant of the freshwater Lake Bonneville whose water level
Externí odkaz:
https://doaj.org/article/0814e7798e17455a997ec303db5a7b2f
Autor:
Tatsuya Togashi, Paul Alan Cox
Darwin identified the existence of separate male and female gametes as one of the central mysteries of evolutionary biology. 150 years later, the question of why male gametes exist remains an intriguing puzzle. In this, the first book solely devoted
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
We sought to identify a usable biomarker from blood samples to characterize early-stage Alzheimer’s disease (AD) patients, in order to facilitate rapid diagnosis, early therapeutic intervention, and monitoring of clinical trials. We compared metabo
Externí odkaz:
https://doaj.org/article/3194f33df803438380dc35814db4f39a
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 104 (2022)
Neurodegenerative diseases feature changes in cognition, and anxiety-like and autism-like behaviors, which are associated with epigenetic alterations such as DNA methylation and histone modifications. The amino acid L-serine has been shown to have be
Externí odkaz:
https://doaj.org/article/0831e0f3095e4801b1cd4015ffe32b5b
Publikováno v:
Open Biology, Vol 10, Iss 6 (2020)
Biomarkers for amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) are currently not clinically available for disease diagnosis or analysis of disease progression. If identified, biomarkers could improve patient outcomes by enabling early in
Externí odkaz:
https://doaj.org/article/79d523ee34dc4c3e903c7a98a7577e75
Autor:
David A. Davis, Susanna P. Garamszegi, Sandra Anne Banack, Patrick D. Dooley, Thomas M. Coyne, Dylan W. McLean, David S. Rotstein, Deborah C. Mash, Paul Alan Cox
Publikováno v:
Toxins, Vol 13, Iss 10, p 697 (2021)
Dolphins are well-regarded sentinels for toxin exposure and can bioaccumulate a cyanotoxin called β-N-methylamino-l-alanine (BMAA) that has been linked to human neurodegenerative disease. The same dolphins also possessed hallmarks of Alzheimer’s d
Externí odkaz:
https://doaj.org/article/7b23ae6f1e82409eae03d546c413000c