Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alan Christesen"'
Autor:
Su Yu, Lakshmi Bhagavatula, Brian J. Kotecki, Travis B. Dunn, Eric G. Moschetta, Westin H. Morrill, Andrew R. Ickes, Troy Reynolds, James C. Marek, Michael J. Rozema, Alan Christesen, Michael Rasmussen, Mathew M. Mulhern
Publikováno v:
Organic Process Research & Development. 26:949-962
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c95c118243fbf10b5043dc6f2d85be
https://doi.org/10.1021/acs.oprd.1c00287
https://doi.org/10.1021/acs.oprd.1c00287
Autor:
Yu-Ming Pu, Yi-Yin Ku, Vincent S. Chan, Michael D. Wendt, Timothy A. Grieme, Alan Christesen, Mathew M. Mulhern
Publikováno v:
The Journal of Organic Chemistry. 84:4814-4829
The process development of a new synthetic route leading to an efficient and robust synthetic process for venetoclax (1: the active pharmaceutical ingredient (API) in Venclexta) is described. The redesigned synthesis features a Buchwald-Hartwig amina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d73ed1e6451b285f5cf09ec6364e62
https://doi.org/10.1021/acs.joc.8b02750
https://doi.org/10.1021/acs.joc.8b02750
Publikováno v:
Tetrahedron Letters. 51:418-421
2,4-Dichloro-5,5-dimethylhydantoin (DCDMH) was found to be a mild and efficient reagent for the direct oxidative conversion of sulfur compounds to the corresponding arenesulfonyl chlorides in good to excellent yields through oxidative chlorination. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af034e72170e380cb222fedfd44975bf
https://doi.org/10.1016/j.tetlet.2009.11.047
https://doi.org/10.1016/j.tetlet.2009.11.047
Autor:
Elaine C. Lee, Eric J. Stoner, Matthew J. Peterson, Jason S. Tedrow, Alan Christesen, Anthony R. Haight, Prasad S. Raje, Seble H. Wagaw, Margaret C. Hsu, Kenneth M. Engstrom, David M. Barnes, Daniel J. Plata
Publikováno v:
Organic Process Research & Development. 10:803-807
The total synthesis of quinolone antibiotic ABT-492 has been achieved in 67% yield over nine steps from 2,4,5-trifluorobenzoic acid. The highlights of this synthesis include a novel chemoselective chlorination at the 8-position of a highly elaborated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b53de99a4bd49e9b48f64647ed7af4
https://doi.org/10.1021/op0600557
https://doi.org/10.1021/op0600557
Autor:
Eric W. Kristensen, Eric J. Stoner, Gregory M. Brill, Alan Christesen, Casey Chun Zhou, Kent D. Stewart, Edmund D. Matayoshi, Steven J. Wittenberger, L. Steven Hollis, Ronald R. Rasmussen
Publikováno v:
Tetrahedron. 60:10611-10618
Oritavancin is a semi-synthetic glycopeptide antibiotic which is structurally related to vancomycin. When oritavancin bisphosphate is dried in vacuo with heat, a new compound forms. This new compound is stable only in the solid state and reverts to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2095a1b5434e682347c40cb775e4e17
https://doi.org/10.1016/j.tet.2004.09.019
https://doi.org/10.1016/j.tet.2004.09.019
Publikováno v:
ChemInform. 41
2,4-Dichloro-5,5-dimethylhydantoin (DCDMH) was found to be a mild and efficient reagent for the direct oxidative conversion of sulfur compounds to the corresponding arenesulfonyl chlorides in good to excellent yields through oxidative chlorination. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4c8677ad7c5be768b7f696356dad2b
https://doi.org/10.1002/chin.201015078
https://doi.org/10.1002/chin.201015078
Autor:
Robert F. Keyes, Kent D. Stewart, Eric J. Stoner, Rodger F. Henry, Michael S. Allen, L. Steven Hollis, Ian Marsden, Sandeep G. Shiroor, Tamara C. Rehm, Niru B. Soni, Alan Christesen
Publikováno v:
The Journal of organic chemistry. 70(8)
A new reaction of erythronolides, an intramolecular hetero-Diels-Alder, has been discovered. Heated aqueous alcoholic solutions of ABT-773 (1) and its cis isomer (3) convert slowly to cycloadducts 2 and 4, respectively. Optimal reaction conditions, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddb285db63a3448922d047e9ea23336
https://pubmed.ncbi.nlm.nih.gov/15823010
https://pubmed.ncbi.nlm.nih.gov/15823010