Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alan C. Herman"'
Autor:
Brian Murphy, Mark C. Manning, Ning Zhang, Robert W. Payne, Alan C. Herman, Ahmad M. Abdul-Fattah, James E. Matsuura, Janice M. Davis
Publikováno v:
Journal of Pharmaceutical Sciences. 101:1941-1946
Autor:
Adrian Distler, Michael J. Treuheit, Sheila R O'conner, Joseph J. Ratto, David Hummel, Alan C. Herman, Gay-May Wu, Janice M. Davis
Publikováno v:
Journal of Chromatography A. 763:337-344
The use of an aqueous sodium chloride-phosphate mobile phase for size-exclusion chromatography of poly(ethylene glycol) modified (PEGylated) proteins resulted in premature degradation of silica-based gel filtration columns. This column degradation wa
Autor:
Alan C. Herman, Karen J. Miller and
Publikováno v:
Analytical Chemistry. 68:3077-3082
An on-line, automated, HPLC method was developed for the separation and detection of recombinant human methionyl granulocyte colony stimulating factor (GCSF) and GCSF modified with poly(ethylene glycol) (PEG-GCSF) in rat serum. The automated method c
Autor:
Brian Murphy, Janice M. Davis, Mark C. Manning, Alan C. Herman, Ning Zhang, James E. Matsuura, Ahmad M. Abdul-Fattah, Robert W. Payne
Publikováno v:
Pharmaceutical development and technology. 18(4)
Eight lyophilized formulations of a IgG1 monoclonal antibody (MAb) were prepared containing increasing levels of sucrose. In addition, three of the formulations had sorbitol added at a level of 5% w/w relative to sucrose. The samples were stored for
Autor:
Ahmad M. Abdul-Fattah, Brian Murphy, Robert W. Payne, Janice M. Davis, Mark C. Manning, Alan C. Herman, James E. Matsuura, Ning Zhang
Publikováno v:
Journal of pharmaceutical sciences. 101(1)
There are many aspects of stabilization of lyophilized proteins. Of these various factors, retention of native structure, having sufficient amount of stabilizer to embed the protein within an amorphous matrix, and dampening β-relaxations have been s
Publikováno v:
Pharmaceutical Biotechnology ISBN: 9780306453328
G-CSF is an extremely well-known and well-characterized molecule. Both the natural glycosylated form and the E. coli-produced nonglycosylated form are biologically active. A thorough understanding of the primary, secondary, and tertiary structures ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e794cfb2d34931492fce5e17c407292
https://doi.org/10.1007/0-306-47452-2_7
https://doi.org/10.1007/0-306-47452-2_7
Publikováno v:
ACS Symposium Series ISBN: 9780841235281
Therapeutic Protein and Peptide Formulation and Delivery
Therapeutic Protein and Peptide Formulation and Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e3dbc2232785c024c347a2cdc3bb018
https://doi.org/10.1021/bk-1997-0675.ch010
https://doi.org/10.1021/bk-1997-0675.ch010
Autor:
Edward S Luedke, Alan C. Herman, Faith E. Ross, Tom Zamborelli, Nicole I. Tedeschi, Che-Hung Yeh
Publisher Summary This chapter describes the application of Edman degradation sequencing in addition to mass spectrometry for the identification of post-translational, acetylation of lysine residues in a recombinant protein expressed in Escherichia c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f28500aa3409911ae3856038de501f
https://doi.org/10.1016/s1080-8914(96)80024-x
https://doi.org/10.1016/s1080-8914(96)80024-x
Autor:
Alan C. Herman, Thomas C. Vanaman
Publikováno v:
Analytical biochemistry. 64(2)
The techniques described in this paper have been used to obtain highly reproducible analytical and preparative peptide separations using small amounts of material (10,11).
Publikováno v:
Virology. 64(2)
Chemical studies of the four major internal polypeptides p27, p19, p15, and p12 from avian myeloblastosis virus (AMV) and the Prague strain of Rous sarcoma virus (PR-RSV) are presented. Tryptic peptide mapping studies show that the individual polypep