Výsledky vyhledávání - "Alan C. Clermont"

Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats

Autor: Shyamali Ghosh, Bart L. DeCorte, Tuman Robert W, S.E. Bursell, William A. Kinney, Alan C. Clermont, Li Liu, Rosemary J. Santulli, Robert A. Galemmo, Norman Huebert, Lynn C. Shaw, Shaker A. Mousa, Dana L. Johnson, Bruce E. Maryanoff, Bruce P. Damiano, Zhao Zhou, Maria B. Grant

Publikováno v: The Journal of pharmacology and experimental therapeutics. 324(3)

The alpha(V) integrins are key receptors involved in mediating cell migration and angiogenesis. In age-related macular degeneration (AMD) and diabetic retinopathy, angiogenesis plays a critical role in the loss of vision. These ocular vasculopathies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7d6910b2d1d109bf1156a0865cdc8b
https://pubmed.ncbi.nlm.nih.gov/18083913

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