Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alan C. B. Smith"'
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :1537-1542
Noise-decoupled pulsed Fourier transform 13C n.m.r. spectra reveal the tacticity in poly(vinyl acetate) and the monomer sequence distribution (MSD) in ethylene (E)–vinyl acetate (V) copolymers. Assignments of carbon absorptions were made from 13C
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :1547-1554
In the 13C n.m.r. spectrum of styrene (S)–methyl methacrylate (M) the aromatic C-1 in the styrene units and the methyl carbon atom in the methyl methacrylate units are sensitive to tacticity in the various monomer sequence triads. Measurements of c
Autor:
Alan C. B. Smith, Maurice W. Partridge
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :453-456
N-Allyl-N′-arylacetamidines have been cyclised, as their hydrochlorides, to 1-aryl-2,5-dimethyl-Δ2-imidazolines and, in polyphosphoric acid, to 3,4-dihydro-4-ethyl-2-methylquinazolines together with, in certain cases, 4,5-dihydro-2,5-dimethyl-3H-1
Autor:
Malcolm Myers, Peter Myers, John F. Saville, Donald S. Walter, Christopher B. Chapleo, Michael R. Stillings, Ian F. Tulloch, Alan C. B. Smith, Anthony P. Welbourn
Publikováno v:
Journal of medicinal chemistry. 29(11)
The synthesis and anticonvulsant activity of a series of 2-aryl-5-hydrazino-1,3,4-thiadiazoles are described. The combination of preferred aromatic substituents in the 2-position coupled with alkyl substitution on the hydrazine moiety led to a number
Autor:
DAVID BREWSTER, MALCOLM MYERS, JOSEPH ORMEROD, PHILIP OTTER, ALAN C. B. SMITH, MARGARET E. SPINNER
Publikováno v:
Chemischer Informationsdienst. 5
Autor:
Ian F. Tulloch, Alan C. B. Smith, Christopher B. Chapleo, Peter Myers, Michael R. Stillings, Donald S. Walter
Publikováno v:
Journal of medicinal chemistry. 31(1)
Two different structural types of 2-aryl-1,3,4-thiadiazole amidines were synthesized and evaluated for anticonvulsant activity. Enhancement of the inherent anticonvulsant activity therein and separation of this activity from the accompanying sedative
Publikováno v:
Journal of the Chemical Society. Perkin transactions 1. 6
Catalytic hydrogenation and treatment with nucleophiles (Grignard reagent, alkoxide ions, morpholine) results in loss of chlorine from the thebaine–2-chloroacrylonitrile adduct. The products of the latter reactions are derived from the C-7 carbanio
Autor:
Ian F. Tulloch, Christopher B. Chapleo, Alan C. B. Smith, Stephen Turner, Peter Myers, Donald S. Walter
Publikováno v:
Journal of Medicinal Chemistry. 32:2582-2582
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :401
The structure of 8,14-but-1-eno-18-ethyl-7,8-dihydro-19-methylcodeinone is confirmed by mass spectrometry and X-ray crystallography. The chemical reactivity of the extra ring is examined.
Autor:
Stephen Turner, Philip Otter, Malcolm Myers, David Brewster, J. A. Ormerod, Margaret E. Spinner, Alan C. B. Smith
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2796
Application of the principles of synthesis design to the problem of prostaglandins led to many possible routes, including one commencing with endo-dicyclopentadiene. This starting material was then converted into racemic prostaglandin F2α in a minim