Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alan C-Y Hsu"'
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6613-6630 (2015)
Enterovirus 71 (EV71) is a major infectious disease affecting millions of people worldwide and it is the main etiological agent for outbreaks of hand foot and mouth disease (HFMD). Infection is often associated with severe gastroenterological, pulmon
Externí odkaz:
https://doaj.org/article/754ad9ae3c8e4f7f890b33269db0e082
Autor:
Prabuddha S. Pathinayake, Alan C.-Y. Hsu, David W. Waters, Philip M. Hansbro, Lisa G. Wood, Peter A. B. Wark
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Asthma is a heterogeneous, chronic inflammatory disease of the airways. It is a complex disease with different clinical phenotypes and results in a substantial socioeconomic burden globally. Poor understanding of pathogenic mechanisms of the disease
Externí odkaz:
https://doaj.org/article/f186a5f15c4d4be1a806aa5b6f13b614
Autor:
Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184260 (2017)
The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecula
Externí odkaz:
https://doaj.org/article/90365bbb82034734925b72509ab31da5
Autor:
Jemma R. Mayall, Prabuddha S. Pathinayake, Guoqiang Wang, Jay C. Horvat, Fang Wang, Katie Daly, Philip M. Hansbro, Peter A. B. Wark, Andrew T. Reid, Alan C-Y. Hsu, Punnam Chander Veerati
SummarySARS-CoV-2 infection causes an inflammatory cytokine storm and acute lung injury. Currently there are no effective antiviral and/or anti-inflammatory therapies. Here we demonstrate that 2019 SARS-CoV-2 spike protein subunit 1 (CoV2-S1) induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e9ff3f4b7a81be0f3af753d958260b
https://doi.org/10.1101/2020.09.30.317818
https://doi.org/10.1101/2020.09.30.317818
Autor:
Alan C-Y. Hsu, Su-Ling Loo, Peter A. B. Wark, Camille Esneau, Nathan W. Bartlett, Kristy Nichol
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
The recurrent emergence of novel, pathogenic coronaviruses (CoVs) severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1; 2002), Middle East respiratory syndrome (MERS)-CoV (2012), and most recently SARS-CoV-2 (2019) has highlighted the need for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316f6212ecc8386eda6cf48a99a5f362
https://pubmed.ncbi.nlm.nih.gov/32903043
https://pubmed.ncbi.nlm.nih.gov/32903043
Autor:
Alan C-Y Hsu, Kristy Parsons, Ian Barr, Sue Lowther, Deborah Middleton, Philip M Hansbro, Peter A B Wark
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32947 (2012)
Innate antiviral responses in bronchial epithelial cells (BECs) provide the first line of defense against respiratory viral infection and the effectiveness of this response is critically dependent on the type I interferons (IFNs). However the importa
Externí odkaz:
https://doaj.org/article/0eef907b001041e69763837f978366c0
Autor:
Anthony Kicic, Fatemeh Moheimani, Aandrew T. Reid, Philip M. Hansbro, Peter A. B. Wark, Stephen M. Stick, Alan C-Y. Hsu, Teresa Williams, Darryl A. Knight
Publikováno v:
Respiratory Research
© 2016 The Author(s). Asthma is a global health problem with increasing prevalence. The airway epithelium is the initial barrier against inhaled noxious agents or aeroallergens. In asthma, the airway epithelium suffers from structural and functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0059c7858c329c10505641c0eea67aac
http://europepmc.org/articles/PMC5034566
http://europepmc.org/articles/PMC5034566
Publikováno v:
Respirology (Carlton, Vic.). 17(8)
Influenza presents a unique human infectious disease that has a substantial impact on the public health, in general, and especially for those with chronic airways diseases. People with asthma and chronic obstructive pulmonary disease (COPD) are parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8185bef4641720c9a5c80eb2ba7d1f74
https://pubmed.ncbi.nlm.nih.gov/22616906
https://pubmed.ncbi.nlm.nih.gov/22616906
Autor:
Caohuy, Hung1,2,3 (AUTHOR), Eidelman, Ofer1,2 (AUTHOR), Chen, Tinghua1,2,3 (AUTHOR), Mungunsukh, Ognoon1,3,4 (AUTHOR), Yang, Qingfeng1,5 (AUTHOR), Walton, Nathan I.1,2,3 (AUTHOR), Pollard, Bette S.6 (AUTHOR), Khanal, Sara7,8 (AUTHOR), Hentschel, Shannon7,9 (AUTHOR), Florez, Catalina7,8 (AUTHOR), Herbert, Andrew S.7 (AUTHOR), Pollard, Harvey B.1,2,3 (AUTHOR) harvey.pollard@usuhs.edu
Publikováno v:
Scientific Reports. 7/23/2024, Vol. 14 Issue 1, p1-16. 16p.
Autor:
Pathinayake, Prabuddha S., Hsu, Alan C.-Y., Nichol, Kristy S., Horvat, Jay C., Hansbro, Philip M., Wark, Peter A. B.
Publikováno v:
American Journal of Physiology: Lung Cellular & Molecular Physiology; May2024, Vol. 326 Issue 5, pL618-L626, 9p