Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Alan Bruce, Lyons"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The Tasmanian devil facial tumor (DFT) disease has led to an 80% reduction in the wild Tasmanian devil (Sarcophilus harrisii) population since 1996. The limited genetic diversity of wild devils and the lack of MHC-I expression on DFT cells have been
Externí odkaz:
https://doaj.org/article/478231e664964cc8a0ef8b9ac16b931a
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The absence of tumor necrosis factor (TNF) causes lethal infection by Leishmania major in normally resistant C57BL/6J (B6.WT) mice. The underlying pathogenic mechanism of this fatal disease has so far remained elusive. We found that B6.WT mice defici
Externí odkaz:
https://doaj.org/article/6605c751b7be4fbca61874fd1167b160
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Immune checkpoint molecules function as a system of checks and balances that enhance or inhibit immune responses to infectious agents, foreign tissues, and cancerous cells. Immunotherapies that target immune checkpoint molecules, particularly the inh
Externí odkaz:
https://doaj.org/article/7977ac92dfbd49dca7806dba5934aee6
Autor:
Andrew Steven Flies, Alan Bruce Lyons, Lynn M Corcoran, Anthony T Papenfuss, James M Murphy, Graeme W Knowles, Greg M Woods, John Dominic Hayball
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The devil facial tumor disease (DFTD) is caused by clonal transmissible cancers that have led to a catastrophic decline in the wild Tasmanian devil (Sarcophilus harrisii) population. The first transmissible tumor, now termed DFT1, was first discovere
Externí odkaz:
https://doaj.org/article/d480b998d4524762a12246c67660e12b
Autor:
Alan Bruce Lyons, Susanne Heinzel
Publikováno v:
Immunology & Cell Biology. 98:712-714
The Ki67 protein is proposed to have two conformations; one which segregates chromosomes before anaphase, and the other which results in chromosome condensation after cell division to exclude large cytosolic components from the reforming nuclei of da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be7ba35618a4f2f0c005a25cfe034b2c
https://doi.org/10.1111/imcb.12395
https://doi.org/10.1111/imcb.12395
Autor:
Ruth J. Pye, Carolyn J. Hogg, Gregory M. Woods, David Pemberton, Scott Carver, Samantha Fox, Jocelyn M. Darby, Kate Swift, J. Elmer, Alan Bruce Lyons, Andrew S. Flies
Disease is increasingly becoming a driver of wildlife population declines and extinction risk. Vaccines have been one of the most successful health interventions in human history, but few have been tested for mitigating wildlife disease. The transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20a280d42e0c3bcdf5660ba3b984332f
https://doi.org/10.1101/2020.12.06.408963
https://doi.org/10.1101/2020.12.06.408963
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Chemokines and their cognate receptors have been identified as major factors initiating and governing cell movement and interaction. These ligands and their receptors are expressed on a wide variety of cells and act during steady-state migration as w
Externí odkaz:
https://doaj.org/article/861779369d27494e829dddff75d4acab
Autor:
Guei-Sheung Liu, Samantha Fox, Ruth J. Pye, Amy T. Gilbert, Andrew S. Flies, Johnson, Emily J. Flies, Amanda L. Patchett, Alan Bruce Lyons, David Pemberton
Publikováno v:
Expert review of vaccines. 19(1)
Introduction: The Tasmanian devil (Sarcophilus harrisii) is the largest extant carnivorous marsupial. Since 1996, its population has declined by 77% primarily due to a clonal transmissible tumor, known as devil facial tumor (DFT1) disease. In 2014, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c030ec52929e73cae2b2a3c90a45c0
https://pubmed.ncbi.nlm.nih.gov/31971036
https://pubmed.ncbi.nlm.nih.gov/31971036
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology, Vol 9 (2019)
The Tasmanian devil facial tumor (DFT) disease has led to an 80% reduction in the wild Tasmanian devil (Sarcophilus harrisii) population since 1996. The limited genetic diversity of wild devils and the lack of MHC-I expression on DFT cells have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7029c450516cf909eb17f7429d3bb168
https://pubmed.ncbi.nlm.nih.gov/30692995
https://pubmed.ncbi.nlm.nih.gov/30692995
Publikováno v:
Vaccine. 33:3016-3025
Tasmanian devils (Sarcophilus harrisii) risk extinction from a contagious cancer, devil facial tumour disease (DFTD) in which the infectious agent is the tumor cell itself. Because devils are unable to produce an immune response against the tumor cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cfd8788554360b30b73f83840db0b38
https://doi.org/10.1016/j.vaccine.2015.01.039
https://doi.org/10.1016/j.vaccine.2015.01.039