Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Alan Bainbridge"'
Autor:
Carolyna Hepburn, Alexis Jones, Alan Bainbridge, Coziana Ciurtin, Juan Eugenio Iglesias, Hui Zhang, Margaret A Hall-Craggs, Timothy J P Bray
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284508 (2023)
Qualitative visual assessment of MRI scans is a key mechanism by which inflammation is assessed in clinical practice. For example, in axial spondyloarthritis (axSpA), visual assessment focuses on the identification of regions with increased signal in
Externí odkaz:
https://doaj.org/article/c92afba6833d402d9377e4c380e74504
Autor:
Vinita Verma, Frederic Lange, Alan Bainbridge, Kelly Harvey-Jones, Nicola J. Robertson, Ilias Tachtsidis, Subhabrata Mitra
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Brain tissue temperature is a dynamic balance between heat generation from metabolism, passive loss of energy to the environment, and thermoregulatory processes such as perfusion. Perinatal brain injuries, particularly neonatal encephalopathy, and se
Externí odkaz:
https://doaj.org/article/4458399b3f164d3b96c48e3db82512cf
Autor:
Sean R Mathieson, Emily L Webb, Moffat Nyirenda, Nicola J Robertson, J Mugalu, Guillaume Gilbert, A Nabawanuka, Kathryn Martinello, J Bwambale, Samson Lubowa, Alan Bainbridge, H Ssebombo, Latha Srinivasan, Cornelia Hagmann, Cathy Morgan, Pia Wintermark, Frances M Cowan, Cally J Tann, Geraldine B Boylan, Annettee Nakimuli, Samantha Sadoo, Carol Nanyunja, Michael Kawooya, Ivan Mambule, Kirsty Le Doare
Publikováno v:
Gates Open Research, Vol 6 (2022)
BACKGROUND: Neonatal encephalopathy (NE) is a leading cause of child mortality worldwide and contributes substantially to stillbirths and long-term disability. Ninety-nine percent of deaths from NE occur in low-and-middle-income countries (LMICs). Wh
Externí odkaz:
https://doaj.org/article/c957083d915c472e989fec5d4110fe6d
Autor:
Adriana Consorte-McCrea, Ana Fernandez, Alan Bainbridge, Andrew Moss, Anne-Caroline Prévot, Susan Clayton, Jenny Anne Glikman, Maria Johansson, José Vicente López-Bao, Alistair Bath, Beatrice Frank, Silvio Marchini
Publikováno v:
Nature Conservation, Vol 37, Iss , Pp 133-150 (2019)
Addressing the biodiversity crisis requires renewed collaborative approaches. Large carnivores are ambassador species, and as such they can aid the protection of a wide range of species, including evolutionarily distinct and threatened ones, while be
Externí odkaz:
https://doaj.org/article/64a81c49a09b44ee8df106b5bc68b0ba
Autor:
Nicola J. Robertson, Kathryn Martinello, Ingran Lingam, Adnan Avdic-Belltheus, Christopher Meehan, Daniel Alonso-Alconada, Sara Ragab, Alan Bainbridge, Magdalena Sokolska, Mohamed Tachrount, Benita Middleton, David Price, Mariya Hristova, Xavier Golay, Annamaria Soliani Raschini, Giancarlo Aquino, Nicola Pelizzi, Fabrizio Facchinetti
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 240-251 (2019)
Therapeutic hypothermia is only partially protective for neonatal encephalopathy; there is an urgent need to develop treatments that augment cooling. Our objective was to assess safety, efficacy and pharmacokinetics of 5 and 15 mg/kg/24 h melatonin (
Externí odkaz:
https://doaj.org/article/7daf6abf1444477d8d26b24a12891d49
Autor:
Raymand Pang, Kathryn A. Martinello, Christopher Meehan, Adnan Avdic-Belltheus, Ingran Lingam, Magda Sokolska, Tatenda Mutshiya, Alan Bainbridge, Xavier Golay, Nicola J. Robertson
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Despite therapeutic hypothermia, survivors of neonatal encephalopathy have high rates of adverse outcome. Early surrogate outcome measures are needed to speed up the translation of neuroprotection trials. Thalamic lactate (Lac)/N-acetylaspartate (NAA
Externí odkaz:
https://doaj.org/article/cb3c1094922b43c5b22938f1f1897e34
Autor:
Kevin D. Broad, Igor Fierens, Bobbi Fleiss, Eridan Rocha-Ferreira, Mojgan Ezzati, Jane Hassell, Daniel Alonso-Alconada, Alan Bainbridge, Go Kawano, Daqing Ma, Ilias Tachtsidis, Pierre Gressens, Xavier Golay, Robert D. Sanders, Nicola J. Robertson
Publikováno v:
Neurobiology of Disease, Vol 87, Iss , Pp 29-38 (2016)
Cooling to 33.5 °C in babies with neonatal encephalopathy significantly reduces death and disability, however additional therapies are needed to maximize brain protection. Following hypoxia–ischemia we assessed whether inhaled 45–50% Argon from
Externí odkaz:
https://doaj.org/article/1f2df732f28b4bcc9885f28dd3d854da
Autor:
Konstantinos C. Fragkos, María Claudia Picasso Bouroncle, Shankar Kumar, Lucy Caselton, Alex Menys, Alan Bainbridge, Stuart A. Taylor, Francisco Torrealdea, Tomoko Kumagai, Simona Di Caro, Farooq Rahman, Jane Macnaughtan, Manil D. Chouhan, Shameer Mehta
Publikováno v:
Nutrients, Vol 12, Iss 7, p 2151 (2020)
(1) Background: Intestinal failure-associated liver disease (IFALD) in adults is characterized by steatosis with variable progression to fibrosis/cirrhosis. Reference standard liver biopsy is not feasible for all patients, but non-invasive serologica
Externí odkaz:
https://doaj.org/article/168ee398bfe349ec8243d429164a3167
Autor:
Timothy J P Bray, Saurabh Singh, Arash Latifoltojar, Kannan Rajesparan, Farzana Rahman, Priya Narayanan, Sahar Naaseri, Andre Lopes, Alan Bainbridge, Shonit Punwani, Margaret A Hall-Craggs
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180562 (2017)
To determine which of four Dixon image types [in-phase (IP), out-of-phase (OP), fat only (FO) and water-only (WO)] is most sensitive for detecting multiple myeloma (MM) focal lesions on whole body MRI (WB-MRI) images.Thirty patients with clinically-s
Externí odkaz:
https://doaj.org/article/e7e7a678581d4e7aa4e640e32c253f13
Autor:
Matthew Caldwell, Tracy Moroz, Tharindi Hapuarachchi, Alan Bainbridge, Nicola J Robertson, Chris E Cooper, Ilias Tachtsidis
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140171 (2015)
Hypoxia-ischaemia (HI) is a major cause of neonatal brain injury, often leading to long-term damage or death. In order to improve understanding and test new treatments, piglets are used as preclinical models for human neonates. We have extended an ea
Externí odkaz:
https://doaj.org/article/c1eca2336e034265a6b6eab535a4186f