Výsledky vyhledávání - "Alan B. Prosser"

Mono-6-( O -2,4,6-triisopropylbenzenesulfonyl)-γ-cyclodextrin, a novel intermediate for the synthesis of mono-functionalised γ-cyclodextrins

Autor: Grove Simon James Anthony, Zhang Mingqiang, Ronald Palin, Alan B. Prosser

Publikováno v: Tetrahedron Letters. 42:8897-8899

A reaction between γ-cyclodextrin (γ-CD) and 2,4,6-triisopropylbenzenesulfonyl chloride in pyridine gave mono-6-( O -2,4,6-triisopropylbenzenesulfonyl)-γ-cyclodextrin in good yield (∼69%) and high purity (>98%). In contrast to other sulfonylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77191050be7fd77dbb22b6993d64e6a7
https://doi.org/10.1016/s0040-4039(01)01934-7

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ChemInform Abstract: Mono-6-(O-2,4-6-triisopropylbenzenesulfonyl)-γ-cyclodextrin, a Novel Intermediate for the Synthesis of Mono-Functionalized γ-Cyclodextrins

Autor: Ronald Palin, Grove Simon James Anthony, Alan B. Prosser, Zhang Mingqiang

Publikováno v: ChemInform. 33

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b42a04d6d960858114ac64a56b02e4a
https://doi.org/10.1002/chin.200208231

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Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block

Autor: Phill Cowley, Ronald Palin, John K. Clark, Alan B. Prosser, Eleanor Pow, Zhang Mingqiang, Robert Taylor, Alan W. Muir

Publikováno v: Bioorganicmedicinal chemistry letters. 12(18)

A series benzylpiperidinium and benzylpyridinium quaternary salts have been synthesised and tested for inhibition of acetylcholinesterase and reversal of neuromuscular block induced by vecuronium. Several potent reversal agents have been identified a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80345d7ab02782a44e38ffe7c6e18c10
https://pubmed.ncbi.nlm.nih.gov/12182861

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Novel piperidinium and pyridinium agents as water-soluble acetylcholinesterase inhibitors for the reversal of neuromuscular blockade

Autor: Eleanor Pow, Phill Cowley, Ronald Palin, Robert Taylor, Zhang Mingqiang, John K. Clark, Alan B. Prosser, Alan W. Muir

Publikováno v: Bioorganicmedicinal chemistry letters. 12(18)

A series of piperidinium and pyridinium agents containing a common structural fragment of 5,6-dimethoxybenzothiophene have been synthesised as water-soluble acetylcholinesterase inhibitors. Several compounds, for example 42 (AChE IC(50) 0.03 microM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c238327b888dd87cc34dfcf8ee4b0d
https://pubmed.ncbi.nlm.nih.gov/12182862

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