Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alan B. Chan"'
Autor:
Vinícius Barreto Garcia, Thaís Gomes de Carvalho, Luiz Henrique da Silva Gasparotto, Heloiza Fernanda Oliveira da Silva, Aurigena Antunes de Araújo, Gerlane Coelho Bernardo Guerra, Timo Schomann, Luis J. Cruz, Alan B. Chan, Raimundo Fernandes de Araújo Júnior
Publikováno v:
Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-12 (2019)
Abstract For many cancers, early detection is the key to improve survival and reduce the morbidity, which is associated with radical resections due to late diagnosis. Here, we describe the efficiency of primary antibody-conjugated gold nanoparticles
Externí odkaz:
https://doaj.org/article/d1deae02b1854c41bae63e66d5db479b
Autor:
Carla Jorquera-Cordero, Pablo Lara, Luis J. Cruz, Timo Schomann, Anna van Hofslot, Thaís Gomes de Carvalho, Paulo Marcos Da Matta Guedes, Laura Creemers, Roman I. Koning, Alan B. Chan, Raimundo Fernandes de Araujo Junior
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1068 (2022)
One of the main reasons for cancer’s low clinical response to chemotherapeutics is the highly immunosuppressive tumor microenvironment (TME). Tumor-ass ociated M2 macrophages (M2-TAMs) orchestrate the immunosuppression, which favors tumor progressi
Externí odkaz:
https://doaj.org/article/2298cbe650d74e21902bc81b9e8ba0bf
Autor:
Pablo Lara, Ruben V. Huis in ‘t Veld, Carla Jorquera-Cordero, Alan B. Chan, Ferry Ossendorp, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1547 (2021)
Photodynamic therapy (PDT) is a promising and clinically approved method for the treatment of cancer. However, the efficacy of PDT is often limited by the poor selectivity and distribution of the photosensitizers (PS) toward the malignant tumors, res
Externí odkaz:
https://doaj.org/article/cb70fb398e204d1c89330592922693ad
Autor:
Maria Laura de Souza Lima, Caroline Addison Carvalho Xavier de Medeiros, Gerlane Coelho Bernardo Guerra, Robson Santos, Michael Bader, Flavia Q. Pirih, Raimundo Fernandes de Araújo Júnior, Alan B. Chan, Luis J. Cruz, Gerly Anne de Castro Brito, Renata Ferreira de Carvalho Leitão, Ericka Janine Dantas da Silveira, Vinicius Barreto Garcia, Agnes Andrade Martins, Aurigena Antunes de Araújo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5217 (2021)
Background: The aim of this study was to evaluate the role of AT1 and AT2 receptors in a periodontal inflammation experimental model. Methods: Periodontal inflammation was induced by LPS/Porphyromonas gingivalis. Maxillae, femur, and vertebra were sc
Externí odkaz:
https://doaj.org/article/e964afffadf54bd48b5fa7d987fff233
Autor:
Ana Luiza C. de S. L. Oliveira, Raimundo Fernandes de Araújo Júnior, Thaís Gomes de Carvalho, Alan B. Chan, Timo Schomann, Filippo Tamburini, Lioe-Fee de Geus-Oei, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 193 (2020)
Apoptosis signaling pathways, drug resistance, and metastasis are important targets to develop new cancer treatments. We developed cholesterol-coated Poly(d,l-Lactide-co-Glycolic Acid) (PLGA) nanoparticles for effective encapsulation and delivery of
Externí odkaz:
https://doaj.org/article/db3272fd3be54223a3ed7e1b0f133785
Autor:
Marieke A. Stammes, Hendrica A. J. M. Prevoo, Meyke C. Ter Horst, Stéphanie A. Groot, Cornelis J. H. Van de Velde, Alan B. Chan, Lioe-Fee de Geus-Oei, Peter J. K. Kuppen, Alexander L. Vahrmeijer, Elena B. Pasquale, Cornelis F. M. Sier
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 307 (2017)
Targeted image-guided oncologic surgery (IGOS) relies on the recognition of cell surface-associated proteins, which should be abundantly present on tumor cells but preferably absent on cells in surrounding healthy tissue. The transmembrane receptor t
Externí odkaz:
https://doaj.org/article/d425daec48ed4472a3e6dd008f5bc9ac
Autor:
Raimundo Fernandes de Araújo Júnior, George A Lira, Timo Schomann, Rômulo S Cavalcante, Natalia Feitosa Vilar, Regina Célia Monteiro de Paula, Raelle Ferreira Gomes, Chih Kit Chung, Carla Jorquera-Cordero, Olena Vepris, Alan B Chan, Luis J. Cruz
Publikováno v:
Translational Oncology, Vol 31, Iss , Pp 101647- (2023)
Tumour-associated macrophages (TAMs) often promote cancer progression through immunosuppression in the tumour microenvironment (TME). However, the signalling pathways crosstalk responsible for this mechanism remain unclear. The aim of our study was t
Externí odkaz:
https://doaj.org/article/1ad0cf4f16454bd89fc185bf2a381c4e