Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Alan B, Brown"'
Autor:
Mohammed B. Alshammari, Ashraf A. Aly, Bahaa G. M. Youssif, Stefan Bräse, Akil Ahmad, Alan B. Brown, Mahmoud A. A. Ibrahim, Asmaa H. Mohamed
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Thiourea derivatives of uracil were efficiently synthesized via the reaction of 5-aminouracil with isothiocyanates. Then, we prepared uracil-containing thiazoles via condensation of thioureas with diethyl/dimethyl acetylenedicarboxylates. The structu
Externí odkaz:
https://doaj.org/article/083e7d11dc634b0892b7c23158fb3bac
Autor:
Essmat M. El-Sheref, Mohamed A. Ameen, Kamal M. El-Shaieb, Fathy F. Abdel-Latif, Asmaa I. Abdel-naser, Alan B. Brown, Stefan Bräse, Hazem M. Fathy, Iqrar Ahmad, Harun Patel, Hesham A. M. Gomaa, Bahaa G. M. Youssif, Asmaa H. Mohamed
Publikováno v:
Molecules, Vol 27, Iss 24, p 8765 (2022)
Our investigation includes the synthesis of new naphthalene-bis-triazole-bis-quinolin-2(1H)-ones 4a–e and 7a–e via Cu-catalyzed [3 + 2] cycloadditions of 4-azidoquinolin-2(1H)-ones 3a–e with 1,5-/or 1,8-bis(prop-2-yn-1-yloxy)naphthalene (2) or
Externí odkaz:
https://doaj.org/article/4e4501f3216848af8481e48ec7fe5543
Autor:
Yaseen A. M. M. Elshaier, Ashraf A. Aly, Mohamed Abdel-Aziz, Hazem M. Fathy, Alan B. Brown, Stefan Bräse, Mohamed Ramadan
Publikováno v:
Molecules, Vol 27, Iss 20, p 7126 (2022)
Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, w
Externí odkaz:
https://doaj.org/article/570488fbb7cb44e0b5d4e34471f5ac5b
Autor:
Asmaa H. Mohamed, Sara M. Mostafa, Ashraf A. Aly, Alaa A. Hassan, Esraa M. Osman, AbdElAziz A. Nayl, Alan B. Brown, Elshimaa M. N. Abdelhafez
Publikováno v:
RSC Advances. 13:14631-14640
In an attempt to develop effective and safe antibacterial agents, thiazinanones bearing the quinolone scaffold were prepared by reaction of the corresponding (quinolinylmethylene)hydrazinecarbothioamides with 2,3-diphenylcycloprop-2-enone.
Publikováno v:
Biomacromolecules. 23:5137-5147
Collagen methacrylation is a promising approach to generate photo-cross-linkable cell-laden hydrogels with improved mechanical properties. However, the impact of species-based variations in amino acid composition and collagen isolation method on meth
Autor:
Essmat M. El-Sheref, Mohammed A. I. Elbastawesy, Alan B. Brown, Ahmed M. Shawky, Hesham A. M. Gomaa, Stefan Bräse, Bahaa G. M. Youssif
Publikováno v:
Molecules, Vol 26, Iss 22, p 6798 (2021)
A mild and versatile method based on Cu-catalyzed [2+3] cycloaddition (Huisgen-Meldal-Sharpless reaction) was developed to tether 3,3’-((4-(prop-2-yn-1-yloxy)phenyl)methylene)bis(4-hydroxyquinolin-2(1H)-ones) with 4-azido-2-quinolones in good yield
Externí odkaz:
https://doaj.org/article/7610b55466f44c70935154c1ed148189
Autor:
Ashraf A. Aly, Alan B. Brown, Mohamad Ramadan, Mohamed Abd El-Aziz, Stefan Bräsee, Hazem M. Fathy
Publikováno v:
ARKIVOC, Vol 2016, Iss 6, Pp 92-104 (2017)
Externí odkaz:
https://doaj.org/article/54e301a1e12a4392816caf6cfefc9190
Autor:
Alan B. Brown, Yaseen A.M.M. Elshaier, Mohamed Abd El-Aziz, Hazem M. Fathy, Stefan Bräse, Martin Nieger, Mohamed Ramadan, Ashraf A. Aly
Publikováno v:
Journal of Sulfur Chemistry. 43:215-231
Regioselective synthesis of quinolone-1,2,4-triazoles was established starting from 4-hydroxyquinol-2-ones. The strategy started by the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, whi
Autor:
Essmat M. El-Sheref, Ashraf A. Aly, Mohammed B. Alshammari, Alan B. Brown, Sara Mohamed Naguib Abdel-Hafez, Walaa Yehia Abdelzaher, Stefan Bräse, ElShimaa M. N. Abdelhafez
Publikováno v:
Molecules, Vol 25, Iss 21, p 5057 (2020)
A series of novel 1,2,3-triazoles hybridized with two quinolin-2-ones, was designed and synthesized through click reactions. The structures of the synthesized compounds were elucidated by NMR, IR, and mass spectra in addition to elemental analysis. T
Externí odkaz:
https://doaj.org/article/61db7afaa2ec412388ba8fb8bb73cb8f
Autor:
Ashraf A. Aly, Mohamed Ramadan, Yaseen A.M.M. Elshaier, Alan B. Brown, Mohamed Abd El-Aziz, Hazem M. Fathy
Publikováno v:
Molecular Diversity. 26:2341-2370
The quinoline scaffold has become an important construction motif for the development of new drugs. The quinolones and their heteroannulated derivatives have high importance due to their diverse spectrum of biological activities as antifungal, anti-i