A novel reuptake inhibitor, IP2015, induces erection by increasing central dopamine and peripheral nitric oxide release.

Autor: Comerma-Steffensen S; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.; Department of Biomedical Sciences/Animal Physiology, Faculty of Veterinary, Central University of Venezuela, Caracas, Venezuela.; Initiator Pharma A/S, Copenhagen, Denmark., Kun A; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark., Prat-Duran J; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark., Mogensen S; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark., Alan Albayrak E; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Türkiye., Fais R; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.; Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Munro G; Hoba Therapeutics, Copenhagen, Denmark., Peters D; Initiator Pharma A/S, Copenhagen, Denmark.; DanPET AB, Malmö, Sweden., Simonsen U; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, Aarhus University, Aarhus, Denmark.; Initiator Pharma A/S, Copenhagen, Denmark.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Aug; Vol. 181 (15), pp. 2566-2582. Date of Electronic Publication: 2024 Apr 11.

The Effects of Novel Triazolopyrimidine Derivatives on H2S Production in Lung and Vascular Tonus in Aorta.

Autor: Ozbek EN; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey., Istanbullu H; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir, Turkey., Kızrak U; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey., Alan Albayrak E; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey., Sevin G; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey., Yetik-Anacak G; Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey.; Department of Pharmacology, Faculty of Pharmacy, Acıbadem Mehmet ali Aydınlar University, Istanbul, Turkey.

Publikováno v: Pharmacology [Pharmacology] 2023; Vol. 108 (6), pp. 530-539. Date of Electronic Publication: 2023 Sep 11.