Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Alan A Alfieri"'
Autor:
Subhrajit Saha, Payel Bhanja, Laibin Liu, Alan A Alfieri, Dong Yu, Ekambar R Kandimalla, Sudhir Agrawal, Chandan Guha
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29357 (2012)
Radiation-induced gastrointestinal syndrome (RIGS) is due to the clonogenic loss of crypt cells and villi depopulation, resulting in disruption of mucosal barrier, bacterial invasion, inflammation and sepsis. Intestinal macrophages could recognize in
Externí odkaz:
https://doaj.org/article/7d727bfc45c64adc8bdfcf2efb88765a
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24072 (2011)
Nuclear accidents and terrorism presents a serious threat for mass casualty. While bone-marrow transplantation might mitigate hematopoietic syndrome, currently there are no approved medical countermeasures to alleviate radiation-induced gastrointesti
Externí odkaz:
https://doaj.org/article/39f8b683b26e4445b684f132c7e618c5
Autor:
Payel Bhanja, Subhrajit Saha, Rafi Kabarriti, Laibin Liu, Namita Roy-Chowdhury, Jayanta Roy-Chowdhury, Rani S Sellers, Alan A Alfieri, Chandan Guha
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e8014 (2009)
BACKGROUND:Radiation-induced gastrointestinal syndrome (RIGS) results from a combination of direct cytocidal effects on intestinal crypt and endothelial cells and subsequent loss of the mucosal barrier, resulting in electrolyte imbalance, diarrhea, w
Externí odkaz:
https://doaj.org/article/a6e30c61c9bd4c7bbba7b3c863937333
Autor:
Xin Gao, Wenjun Guo, N. Patrik Brodin, Noboru Asada, Fumio Nakahara, Jessica C. Mar, Chandan Guha, Qiaozhi Wei, Alan A. Alfieri, Dachuan Zhang, Chunliang Xu, Samuel E. Zimmerman, Paul S. Frenette
Publikováno v:
Dev Cell
Bone marrow (BM) mesenchymal stem and progenitor cells (MSPCs) are a critical constituent of the hematopoietic stem cell (HSC) niche. Previous studies have suggested that the zinc-finger epithelial-mesenchymal transition transcription factor Snai2 (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea181821ecb9739e97323f74ca75b33
https://europepmc.org/articles/PMC7299199/
https://europepmc.org/articles/PMC7299199/
Autor:
Alan A. Alfieri, Brandon L. Adler, Adam J. Friedman, Aimee Krausz, Angelo Landriscina, Joel M. Friedman, Hayley M. McDaid, Mahantesh S. Navati, Alicia Rodriguez-Gabin, Kenny Ye, David Schairer, Jamie Rosen, Joshua D. Nosanchuk, Joy Makdisi
Publikováno v:
Precision Nanomedicine
Precision nanomedicine
Precision nanomedicine
The effect of size and release kinetics of doxorubicin-nanoparticles on anti-tumor efficacy was evaluated in a panel of human cancer cell lines, including triple-negative breast cancer (TNBC) cells that frequently demonstrate resistance to doxorubici
Autor:
Angela Gambino, Lorenzo Agoni, Alan A. Alfieri, Gary L. Goldberg, Chandan Guha, E. Premkumar Reddy, Indranil Basu, Seema Gupta
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 88:1180-1187
Purpose To compare rigosertib versus cisplatin as an effective radiosensitizing agent for cervical malignancies. Methods and Materials Rigosertib and cisplatin were tested in cervical cancer cell lines, HeLa and C33A. A 24-hour incubation with rigose
Autor:
Luis R. Martinez, Joshua D. Nosanchuk, Parimala Nacharaju, Joel M. Friedman, Adam J. Friedman, Chaim Tuckman-Vernon, Chandan Guha, David Schairer, Jason Chouake, Alan A. Alfieri, Karin Blecher
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 8:1364-1371
Wound healing is a complex process, coordinated by various biological factors. In immunocompromised states wound healing can be interrupted as a result of decreased numbers of immune cells, impairing the production of effector molecules such as nitri
Autor:
Chandan Guha, Reshma Singh, Anu Wallecha, L. Liu, Raquibul Hannan, John Rothman, Patrice Cohen, H. Zhang, Alan A. Alfieri
Publikováno v:
Cancer Immunology, Immunotherapy. 61:2227-2238
Radiation therapy (RT) is an integral part of prostate cancer treatment across all stages and risk groups. Immunotherapy using a live, attenuated, Listeria monocytogenes-based vaccines have been shown previously to be highly efficient in stimulating
Autor:
Manju Chacko, Leslie Gunther, Adam J. Friedman, Alan A. Alfieri, Mahantesh S. Navati, George Han, Joel M. Friedman
Publikováno v:
Nitric Oxide. 19:12-20
A new platform using biocompatible materials is presented for generating powders comprised of nanoparticles that release therapeutic levels of nitric oxide (NO) in a controlled and sustained manner. The capacity of these particles to retain and gradu
Publikováno v:
Seminars in Nuclear Medicine. 38:105-113
This issue of Seminars in Nuclear Medicine deals with a watershed event in cancer treatment -- the combined use of functional and anatomical information to guide therapeutic interventions. The use of positron emission tomography/computed tomography (