Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Alan, Stuart"'
Autor:
Pratibha Bhai, Benjamin Chin-Yee, Victor Pope, Ian Cheong, Maxim Matyashin, Michael A. Levy, Aidin Foroutan, Alan Stuart, Cyrus C. Hsia, Hanxin Lin, Bekim Sadikovic, Ian Chin-Yee
Publikováno v:
Current Oncology, Vol 29, Iss 10, Pp 7209-7217 (2022)
Background: Since the identification of JAK2 V617F and exon 12 mutations as driver mutations in polycythemia vera (PV) in 2005, molecular testing of these mutations for patients with erythrocytosis has become a routine clinical practice. However, the
Externí odkaz:
https://doaj.org/article/3f897fc6e5724f84ae1912b24b087ec4
Autor:
Pratibha Bhai, Jacob Turowec, Stephanie Santos, Jennifer Kerkhof, LeeAnne Pickard, Aidin Foroutan, Daniel Breadner, Matthew Cecchini, Michael A. Levy, Alan Stuart, Stephen Welch, Christopher Howlett, Hanxin Lin, Bekim Sadikovic
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPersonalized targeted therapies have transformed management of several solid tumors. Timely and accurate detection of clinically relevant genetic variants in tumor is central to the implementation of molecular targeted therapies. To facilit
Externí odkaz:
https://doaj.org/article/aa56f829f46649b0a40108279d31d700
Autor:
Binsheng Gong, Dan Li, Rebecca Kusko, Natalia Novoradovskaya, Yifan Zhang, Shangzi Wang, Carlos Pabón-Peña, Zhihong Zhang, Kevin Lai, Wanshi Cai, Jennifer S. LoCoco, Eric Lader, Todd A. Richmond, Vinay K. Mittal, Liang-Chun Liu, Donald J. Johann, James C. Willey, Pierre R. Bushel, Ying Yu, Chang Xu, Guangchun Chen, Daniel Burgess, Simon Cawley, Kristina Giorda, Nathan Haseley, Fujun Qiu, Katherine Wilkins, Hanane Arib, Claire Attwooll, Kevin Babson, Longlong Bao, Wenjun Bao, Anne Bergstrom Lucas, Hunter Best, Ambica Bhandari, Halil Bisgin, James Blackburn, Thomas M. Blomquist, Lisa Boardman, Blake Burgher, Daniel J. Butler, Chia-Jung Chang, Alka Chaubey, Tao Chen, Marco Chierici, Christopher R. Chin, Devin Close, Jeffrey Conroy, Jessica Cooley Coleman, Daniel J. Craig, Erin Crawford, Angela del Pozo, Ira W. Deveson, Daniel Duncan, Agda Karina Eterovic, Xiaohui Fan, Jonathan Foox, Cesare Furlanello, Abhisek Ghosal, Sean Glenn, Meijian Guan, Christine Haag, Xinyi Hang, Scott Happe, Brittany Hennigan, Jennifer Hipp, Huixiao Hong, Kyle Horvath, Jianhong Hu, Li-Yuan Hung, Mirna Jarosz, Jennifer Kerkhof, Benjamin Kipp, David Philip Kreil, Paweł Łabaj, Pablo Lapunzina, Peng Li, Quan-Zhen Li, Weihua Li, Zhiguang Li, Yu Liang, Shaoqing Liu, Zhichao Liu, Charles Ma, Narasimha Marella, Rubén Martín-Arenas, Dalila B. Megherbi, Qingchang Meng, Piotr A. Mieczkowski, Tom Morrison, Donna Muzny, Baitang Ning, Barbara L. Parsons, Cloud P. Paweletz, Mehdi Pirooznia, Wubin Qu, Amelia Raymond, Paul Rindler, Rebecca Ringler, Bekim Sadikovic, Andreas Scherer, Egbert Schulze, Robert Sebra, Rita Shaknovich, Qiang Shi, Tieliu Shi, Juan Carlos Silla-Castro, Melissa Smith, Mario Solís López, Ping Song, Daniel Stetson, Maya Strahl, Alan Stuart, Julianna Supplee, Philippe Szankasi, Haowen Tan, Lin-ya Tang, Yonghui Tao, Shraddha Thakkar, Danielle Thierry-Mieg, Jean Thierry-Mieg, Venkat J. Thodima, David Thomas, Boris Tichý, Nikola Tom, Elena Vallespin Garcia, Suman Verma, Kimbley Walker, Charles Wang, Junwen Wang, Yexun Wang, Zhining Wen, Valtteri Wirta, Leihong Wu, Chunlin Xiao, Wenzhong Xiao, Shibei Xu, Mary Yang, Jianming Ying, Shun H. Yip, Guangliang Zhang, Sa Zhang, Meiru Zhao, Yuanting Zheng, Xiaoyan Zhou, Christopher E. Mason, Timothy Mercer, Weida Tong, Leming Shi, Wendell Jones, Joshua Xu
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-23 (2021)
Abstract Background Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-l
Externí odkaz:
https://doaj.org/article/c5365bb671514dddbb3d5b324f62ed28
Autor:
Pratibha Bhai, Michael A. Levy, Kathleen Rooney, Deanna Alexis Carere, Jack Reilly, Jennifer Kerkhof, Michael Volodarsky, Alan Stuart, Mike Kadour, Karen Panabaker, Laila C. Schenkel, Hanxin Lin, Peter Ainsworth, Bekim Sadikovic
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
BackgroundHereditary cancer predisposition syndromes account for approximately 10% of cancer cases. Next generation sequencing (NGS) based multi-gene targeted panels is now a frontline approach to identify pathogenic mutations in cancer predispositio
Externí odkaz:
https://doaj.org/article/22fc06b1488549319e08328937c5ba16
Autor:
Eman M. Mansory, Pratibha Bhai, Alan Stuart, Lori Laudenbach, Bekim Sadikovic, Alejandro Lazo‐Langner
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 4, Pp n/a-n/a (2021)
Abstract Congenital prothrombin deficiency is an extremely rare, autosomal recessive bleeding disorder with a prevalence of 1 in 2 million individuals. Here, we report a case of congenital prothrombin deficiency with two concurrent mutations in the p
Externí odkaz:
https://doaj.org/article/3b47b82f81924c3c86505c29a8aad3ce
Autor:
Eric G. Bend, Erfan Aref-Eshghi, David B. Everman, R. Curtis Rogers, Sara S. Cathey, Eloise J. Prijoles, Michael J. Lyons, Heather Davis, Katie Clarkson, Karen W. Gripp, Dong Li, Elizabeth Bhoj, Elaine Zackai, Paul Mark, Hakon Hakonarson, Laurie A. Demmer, Michael A. Levy, Jennifer Kerkhof, Alan Stuart, David Rodenhiser, Michael J. Friez, Roger E. Stevenson, Charles E. Schwartz, Bekim Sadikovic
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-17 (2019)
Abstract Background ADNP syndrome is a rare Mendelian disorder characterized by global developmental delay, intellectual disability, and autism. It is caused by truncating mutations in ADNP, which is involved in chromatin regulation. We hypothesized
Externí odkaz:
https://doaj.org/article/57a3f24470ab45e9a3daea857bcee71b
Autor:
Redouan Qessaoui, Abderrahim Amarraque, Hind Lahmyed, Abdelhadi Ajerrar, El Hassan Mayad, Bouchra Chebli, Alan Stuart Walters, Rachid Bouharroud
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231496 (2020)
In agroecosystems, soil biodiversity is increasingly becoming more recognized as providing benefits to both plants and human health. It performs a wide variety of ecological services beyond the recycling of nutrients to plant growth and manage pests
Externí odkaz:
https://doaj.org/article/fdd39764109b42c78917fad4b24f78d9
Autor:
Redouan Qessaoui, Rachid Bouharroud, Abderrahim Amarraque, Abdelhadi Ajerrar, El Hassan Mayad, Bouchra Chebli, Mokhtara Dadi, Rachid Elaini, Fayssal El Filali, Alan Stuart Walters
Publikováno v:
Journal of Plant Protection Research, Vol 57, Iss 4, Pp 409-416 (2017)
The two-spotted spider mite (Tetranychus urticae Koch) is an important pest of many horticultural crops. A study was conducted to evaluate the effect of three fluorescent Pseudomonas isolates obtained from rhizospheric soil of tomato (Solanum lycop
Externí odkaz:
https://doaj.org/article/0279f6b385c44064be98ff8a66a70e2a
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Autor:
Benjamin, Chin-Yee, Maxim, Matyashin, Ian, Cheong, Pratibha, Bhai, Alejandro, Lazo-Langner, Ala, Almanaseer, Eri, Kawata, Michael A, Levy, Alan, Stuart, Hanxin, Lin, Ian, Chin-Yee, Bekim, Sadikovic, Cyrus, Hsia
Publikováno v:
CMAJ Open. 10:E988-E992
Molecular testing foriJAK2/imutations is part of the standard diagnostic workup for patients with suspected polycythemia vera. We sought to characterize evolving practice patterns in the investigation of erythrocytosis and the prevalence of secondary