Zobrazeno 1 - 10
of 759
pro vyhledávání: '"Alan, Garfinkel"'
Autor:
Meinrat O Andreae, Abdullah Al-Amri, Tracey W Andreae, Alan Garfinkel, Gerald Haug, Klaus Peter Jochum, Brigitte Stoll, Ulrike Weis
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0235421 (2020)
We investigated rock varnish, a thin, manganese- and iron-rich, dark surface crust, on basaltic lava flows and petroglyphs in the Owens and Rose Valleys (California) by portable X-ray fluorescence (pXRF) and femtosecond laser-ablation inductively-cou
Externí odkaz:
https://doaj.org/article/4763216c9ab64e63b71f2758e307a26f
Autor:
Christopher B. Cooper, Alan Garfinkel
Publikováno v:
Journal of Applied Physiology. 133:1081-1092
The kinetic response of oxygen uptake (V̇osub2/sub) to transitions of exercise intensity is one of the important parameters of aerobic function. The typical kinetic response between two steady states can be reasonably well fitted with a mono-exponen
Autor:
Lingyun Xiong, Alan Garfinkel
Publikováno v:
Progress in Biophysics and Molecular Biology. 174:28-40
The tumor suppressor p53 oscillates in response to DNA double-strand breaks, a behavior that has been suggested to be essential to its anti-cancer function. Nearly all human cancers have genetic alterations in the p53 pathway; a number of these alter
Autor:
Zhilin Qu, Michael B. Liu, Riccardo Olcese, Hrayr Karagueuzian, Alan Garfinkel, Peng-Sheng Chen, James N. Weiss
Publikováno v:
Heart Rhythm. 19:1369-1383
Initiation of reentry requires 2 factors: (1) a triggering event, most commonly focal excitations such as premature ventricular complexes (PVCs); and (2) a vulnerable substrate with regional dispersion of refractoriness and/or excitability, such as o
Autor:
Geoffrey L. Kung, Marmar Vaseghi, Jin K. Gahm, Jane Shevtsov, Alan Garfinkel, Kalyanam Shivkumar, Daniel B. Ennis
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: Computational models of the heart increasingly require detailed microstructural information to capture the impact of tissue remodeling on cardiac electromechanics in, for example, hearts with myocardial infarctions. Myocardial infarctio
Externí odkaz:
https://doaj.org/article/be70808497504a67baa0bcb391f98175
Autor:
Aditya V S Ponnaluri, Luigi E Perotti, Michael Liu, Zhilin Qu, James N Weiss, Daniel B Ennis, William S Klug, Alan Garfinkel
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 6, p e1004968 (2016)
Heart failure is a leading cause of death, yet its underlying electrophysiological (EP) mechanisms are not well understood. In this study, we use a multiscale approach to analyze a model of heart failure and connect its results to features of the ele
Externí odkaz:
https://doaj.org/article/f215a631c14e4539a9d2a107fa41b34e
Autor:
Kristina I. Boström, Yucheng Yao, Lily Zhang, Medet Jumabay, Pierre J. Guihard, Yina Guo, Alan Garfinkel, Jiayi Yao, Xiuju Wu
Publikováno v:
Circ Res
Rationale: The BMPs (bone morphogenetic proteins) are essential morphogens in angiogenesis and vascular development. Disruption of BMP signaling can trigger cardiovascular diseases, such as arteriovenous malformations. Objective: A computational mode
Publikováno v:
Bulletin of mathematical biology, vol 84, iss 3
There is a growing realization that traditional “Calculus for Life Sciences” courses do not show their applicability to the Life Sciences and discourage student interest. There have been calls from the AAAS, the Howard Hughes Medical Institute, t
Autor:
Christopher G. Griffis, Janki Mistry, Kendall Islam, Tamara Cutler, Christopher S. Colwell, Alan Garfinkel
Publikováno v:
Chronobiology international. 39(4)
Circadian rhythms in core body temperature (CBT) have been widely studied, but fewer studies have explored higher-frequency (ultradian) rhythms in detail. We analyzed CBT recordings from young and middle-aged wild-type mice as well as from the Q175 m
Autor:
Casey Shapiro, Blaire Van Valkenburgh, Alan Garfinkel, M. Kevin Eagan, William J. Conley, Hannah Whang Sayson, Erin Sanders O’Leary, Marc Levis-Fitzgerald
Publikováno v:
CBE life sciences education, vol 20, iss 4
CBE Life Sciences Education
CBE Life Sciences Education
Calculus is typically one of the first college courses encountered by science, technology, engineering, and mathematics (STEM) majors. Calculus often presents major challenges affecting STEM student persistence, particularly for students from groups