Zobrazeno 1 - 10 of 42 pro vyhledávání: '"Alan, Baer"'
1
Akademický článek
Differential T cell immune responses to deamidated adeno-associated virus vector
Autor: So Jin Bing, Sune Justesen, Wells W. Wu, Abdul Mohin Sajib, Stephanee Warrington, Alan Baer, Stephan Thorgrimsen, Rong-Fong Shen, Ronit Mazor
Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 255-267 (2022)
Despite the high safety profile demonstrated in clinical trials, the immunogenicity of adeno-associated virus (AAV)-mediated gene therapy remains a major hurdle. Specifically, T-cell-mediated immune responses to AAV vectors are related to loss of eff
Externí odkaz: https://doaj.org/article/1b0e9853740c409c867ea3011ba44dc8
Zobrazit plný text záznamu
2
Akademický článek
The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps
Autor: Brendan Antiochos, Daniela Trejo-Zambrano, Paride Fenaroli, Avi Rosenberg, Alan Baer, Archit Garg, Jungsan Sohn, Jessica Li, Michelle Petri, Daniel W Goldman, Christopher Mecoli, Livia Casciola-Rosen, Antony Rosen
Publikováno v: eLife, Vol 11 (2022)
Background: Nucleic acid binding proteins are frequently targeted as autoantigens in systemic lupus erythematosus (SLE) and other interferon (IFN)-linked rheumatic diseases. The AIM-like receptors (ALRs) are IFN-inducible innate sensors that form sup
Externí odkaz: https://doaj.org/article/4190c93887f34785aebea47cdf1069aa
Zobrazit plný text záznamu
3
Akademický článek
Inactivation of Venezuelan Equine Encephalitis Virus Genome Using Two Methods
Autor: Mahgol Behnia, Alan Baer, Andrew M. Skidmore, Caitlin W. Lehman, Nicole Bracci, Kylene Kehn-Hall, Steven B. Bradfute
Publikováno v: Viruses, Vol 14, Iss 2, p 272 (2022)
Venezuelan equine encephalitis virus (VEEV) is an Alphavirus in the Togaviridae family of positive-strand RNA viruses. The viral genome of positive-strand RNA viruses is infectious, as it produces infectious virus upon introduction into a cell. VEEV
Externí odkaz: https://doaj.org/article/27df1218467e4cb384385e4d3c073c2a
Zobrazit plný text záznamu
5
A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity
Autor: Gauri Lamture, Joseph W. Fischer, Nirjal Bhattarai, Winston Colon-Moran, Alan Baer, Jack T. Stapleton
Publikováno v: Gene Therapy. 29:616-623
Viral vector-mediated gene therapies have the potential to treat many human diseases; however, host immune responses against the vector and/or the transgene pose a safety risk to the patients and can negatively impact product efficacy. Thus, novel st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c39f9fe3574cc2abbb74afa3d2a9a6a
https://doi.org/10.1038/s41434-021-00302-5
Zobrazit plný text záznamu
6
Akademický článek
Src-family kinases negatively regulate NFAT signaling in resting human T cells.
Autor: Alan Baer, Winston Colon-Moran, Jinhua Xiang, Jack T Stapleton, Nirjal Bhattarai
Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0187123 (2017)
T cell signaling is required for activation of both natural and therapeutic T cells including chimeric antigen receptor (CAR) T cells. Identification of novel factors and pathways regulating T cell signaling may aid in development of effective T cell
Externí odkaz: https://doaj.org/article/801af321caa545999dca6052adf27080
Zobrazit plný text záznamu
7
A National Survey of Burnout and Depression Among Fellows Training in Pulmonary and Critical Care Medicine
Autor: Scott M. Lieberman, Kristin M. Burkart, Kerry L. Neall, Schartess Culpepper Pace, Apostolos Kontzias, Judith A. Furlong, Morgan I. Soffler, Rahul G. Argula, Maria Danila, Mark H. Adelman, Joseph Barney, Lynn M. Petruzzi, Matthew C. Baker, Charles D. Burger, Chadwick R. Johr, Elliot Rosenstein, Robert Vassallo, Stephen Doyle, Gregory P. Downey, Gretchen Winter, Thomas Eckmann, Jeanne Dale, Richard A. Helmers, Stanley Pillemer, Alan Baer, Tamiko Katsumoto, Keith J. Robinson, Amit Sachdev, Robert M. Kotloff, Vasileios C. Kyttaris, Rendell W. Ashton, Rachana Krishna, Sara S. McCoy, Nora Sandorfi, Kristin A. Riekert, Stamatina J. Danielides, Elizabeth R. Volkmann, Heidi Kukla, Timothy Niewold, Donald Bloch, Jennifer W. McCallister, Michelle Sharp, Jerome L. Greene, Robert I. Fox, Malik M. Khurram S. Khan, Sandra E. Zaeh, Michelle N. Eakin, Kristen L. Veraldi, Stuart S. Kassan, Peter H. Lenz, Daniel J. Wallace, Evelyn J. Bromet, Edward L. Treadwell, Robert F. Spiera, Adrian Shifren, Theresa Lawrence Ford, W. Neal Roberts, Jacqueline O’Toole, Senada Arabelovic, Matthew Koslow, Janet Lewis, Philip Cohen, Rebecca C. Keith, Thomas G. Osborn, Sarah Schafer, Justin C. Hewlett, Paul F. Dellaripa, Scott Zashin, Ruben Peredo-Wende, Chokkalingam Siva, Jay H. Ryu, Jeffrey J. Swigris, Lee Daugherty Biddison, Cynthia S. Rand, Barbara Segal, Daniel Small, Gerald W. Staton, Thomas Grader-Beck, Ghaith Noaiseh, Frederick B. Vivino, Tracy Luckhardt, James Gagermeier, Robert W. Ward, James Topilow, Kirsten Koons, Gabriel T. Bosslet
Publikováno v: Chest. 159:733-742
Background The prevalence of burnout and depressive symptoms is high among physician trainees. Research Question What is the burden of burnout and depressive symptoms among fellows training in pulmonary and critical care medicine (PCCM) and what are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be64614a589ac0a25ca3b5b9c1784401
https://doi.org/10.1016/j.chest.2020.08.2117
Zobrazit plný text záznamu
8
Gain-of-function mutations in
Autor: Christina Torres, Kozycki, Shilpa, Kodati, Laryssa, Huryn, Hongying, Wang, Blake M, Warner, Priyam, Jani, Dima, Hammoud, Mones S, Abu-Asab, Yingyos, Jittayasothorn, Mary J, Mattapallil, Wanxia Li, Tsai, Ehsan, Ullah, Ping, Zhou, Xiaoying, Tian, Ariane, Soldatos, Niki, Moutsopoulos, Marie, Kao-Hsieh, Theo, Heller, Edward W, Cowen, Chyi-Chia Richard, Lee, Camilo, Toro, Shelley, Kalsi, Zohreh, Khavandgar, Alan, Baer, Margaret, Beach, Debra, Long Priel, Michele, Nehrebecky, Sofia, Rosenzweig, Tina, Romeo, Natalie, Deuitch, Laurie, Brenchley, Eileen, Pelayo, Wadih, Zein, Nida, Sen, Alexander H, Yang, Gary, Farley, David A, Sweetser, Lauren, Briere, Janine, Yang, Fabiano, de Oliveira Poswar, Ida Vanessa D, Schwartz, Tamires, Silva Alves, Perrine, Dusser, Isabelle, Koné-Paut, Isabelle, Touitou, Salah Mohamed, Titah, Petrus Martin, van Hagen, Rogier T A, van Wijck, Peter J, van der Spek, Hiromi, Yano, Andreas, Benneche, Ellen M, Apalset, Ragnhild Wivestad, Jansson, Rachel R, Caspi, Douglas Byron, Kuhns, Massimo, Gadina, Hidetoshi, Takada, Hiroaki, Ida, Ryuta, Nishikomori, Elena, Verrecchia, Eugenio, Sangiorgi, Raffaele, Manna, Brian P, Brooks, Lucia, Sobrin, Robert B, Hufnagel, David, Beck, Feng, Shao, Amanda K, Ombrello, Ivona, Aksentijevich, Daniel L, Kastner, Rachel, Mahoney
Publikováno v: Annals of the rheumatic diseases. 81(10)
To test the hypothesis that ROSAH (retinal dystrophy, optic nerve oedema, splenomegaly, anhidrosis and headache) syndrome, caused by dominant mutation inThis cohort study systematically evaluated 27 patients with ROSAH syndrome for inflammatory featu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3e3c21bd5ada9cddabd90227704b7ef
https://pubmed.ncbi.nlm.nih.gov/35868845
Zobrazit plný text záznamu
10
Akademický článek
The use of Nanotrap particles in the enhanced detection of Rift Valley fever virus nucleoprotein.
Autor: Nazly Shafagati, Lindsay Lundberg, Alan Baer, Alexis Patanarut, Katherine Fite, Benjamin Lepene, Kylene Kehn-Hall
Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0128215 (2015)
Rift Valley fever virus (RVFV) is a highly pathogenic arthropod-borne virus that has a detrimental effect on both livestock and human populations. While there are several diagnostic methodologies available for RVFV detection, many are not sensitive e
Externí odkaz: https://doaj.org/article/29dcdfb0b2fe41d1b4f098d47465d301
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje