Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Alamsahebpour A"'
Autor:
Severa Bunda, Pardeep Heir, Julie Metcalf, Annie Si Cong Li, Sameer Agnihotri, Stefan Pusch, Mamatjan Yasin, Mira Li, Kelly Burrell, Sheila Mansouri, Olivia Singh, Mark Wilson, Amir Alamsahebpour, Romina Nejad, Bethany Choi, David Kim, Andreas von Deimling, Gelareh Zadeh, Kenneth Aldape
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Capicua (CIC) is a tumour suppressor in oligodendroglioma. Here, the authors show that ERK activation mediates CIC regulation via ubiquitination and degradation by PJA1 and a degradation resistant form of CIC enhances efficacy of ERK inhibition in gl
Externí odkaz:
https://doaj.org/article/8bad397c36f64a45b7ac70d9557fd054
Autor:
Sahar Eftekharzadeh, Sorena Keihani, Mehdi Fareghi, Alireza Alamsahebpour, Abdol-Mohammad Kajbafzadeh
Publikováno v:
Case Reports in Urology, Vol 2016 (2016)
Type IV sacrococcygeal teratoma is a rare pediatric tumor that is confined to the presacral area with no external component. The signs and symptoms often arise due to mass effect and compression of adjacent organs. Urinary retention is an uncommon pr
Externí odkaz:
https://doaj.org/article/b76df928f4f244eeb9843286f95b395c
Publikováno v:
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 10, Iss 1, Pp 54-59 (2008)
BACKGROUND AND OBJECTIVE: Hirschsprungs disease (HD) is a congenital defect in pediatric patients, which is manifested by bowel obstruction in neonates or constipation in children. The gold standard of diagnosis is absence of ganglionic cells in myen
Externí odkaz:
https://doaj.org/article/abbd4a411f3c402bba5c40fc219199ec
Autor:
Hidas, Guy, Lee, Hak J., Bahoric, Andrej, Kelly, Maryellen S., Watts, Blake, Liu, Zhongbo, Saharti, Samah, Lusch, Achim, Alamsahebpour, Alireza, Kerbl, David, Truong, Hung, Zi, Xiaolin, Khoury, Antoine E.
Publikováno v:
In Journal of Pediatric Urology October 2015 11(5):260-260
Autor:
David Kim, Mira Li, Pardeep Heir, Gelareh Zadeh, Sheila Mansouri, Romina Nejad, Mark R. Wilson, Sameer Agnihotri, Mamatjan Yasin, Andreas von Deimling, Olivia Singh, Kelly Burrell, Bethany Choi, Stefan Pusch, Annie Si Cong Li, Julie Metcalf, Amir Alamsahebpour, Kenneth Aldape, Severa Bunda
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Capicua (CIC) is a transcriptional repressor that counteracts activation of genes downstream of receptor tyrosine kinase (RTK)/Ras/ERK signaling. It is well-established that tumorigenesis, especially in glioblastoma (GBM), is attributed to hyperactiv
Autor:
Mark R. Wilson, Alireza Mansouri, Wenya Linda Bi, Boris Krischek, Peter D. Tonge, Mira Li, Kelly Burrell, Rameen Beroukhim, Arnavaz Danesh, Jonathan R. Krieger, Vera Bril, Mark Dowar, Sameer Agnihotri, Stefano Maria Pagnotta, George Klironomos, Antonio Iavarone, Michael G. Fehlings, Amir Alamsahebpour, Jeff Bruce, Yasin Mamatjan, Shahrzad Jalali, Natalie Landon-Brace, Trevor J. Pugh, Takyee Tung, Gelareh Zadeh, Tiantian Li, Ian F. Dunn, Pankaj K. Agarwalla, Osaama H. Khan, Kenneth Aldape
Publikováno v:
Nature Genetics. 48:1339-1348
Schwannomas are common peripheral nerve sheath tumors that can cause debilitating morbidities. We performed an integrative analysis to determine genomic aberrations common to sporadic schwannomas. Exome sequence analysis with validation by targeted D
Autor:
Sheila Mansouri, Kelly Burrell, Alenoush Vartanian, Mark R. Wilson, Shahrzad Jalali, Peter D. Tonge, Amir Alamsahebpour, Michael S. Taccone, Kenneth Aldape, Sameer Agnihotri, Brian Golbourn, Gelareh Zadeh
Publikováno v:
Oncotarget
First-line cancer therapies such as alkylating agents and radiation have limited survival benefits for Glioblastoma (GBM) patients. Current research strongly supports the notion that inhibition of aberrant tumor metabolism holds promise as a therapeu
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Autor:
Sheila Mansouri, Sanjay Singh, Merve Karabork, Kelly Burrell, Kenneth Aldape, Bradly G. Wouters, Gelareh Zadeh, Ihsan Solaroglu, Amir Alamsahebpour, Jeffery T. Chang, Can Ekinci, Mira Li, Elizabeth Koch
Publikováno v:
Oncotarget
The RNAse III endonuclease DICER is a key regulator of microRNA (miRNA) biogenesis and is frequently decreased in a variety of malignancies. We characterized the role of DICER in glioblastoma (GB), specifically demonstrating its effects on the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6110abd22f43256aab3192349f7c62c0
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/617
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/617
Publikováno v:
Journal of Pediatric Surgery. 48:e13-e16
We present a rare case of female newborn that presented with atypical genitalia, vaginal atresia and a short segment rectal stenosis which was successfully managed in a minimally invasive fashion using urological endoscopic and balloon dilatation tec