Exome-based case-control association study using extreme phenotype design reveals novel candidates with protective effect in diabetic retinopathy.

Autor: Shtir C; Population Genomics, Life Sciences Solutions, Thermo Fisher Scientific, Carlsbad, CA, 92008, USA., Aldahmesh MA; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Al-Dahmash S; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Abboud E; Retina Department, Eye Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE., Alkuraya H; Department of Ophthalmology, Specialized Medical Center Hospital, Riyadh, Saudi Arabia., Abouammoh MA; Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Nowailaty SR; Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia., Al-Thubaiti G; Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia., Naim EA; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Saudi Human Genome Project, Riyadh, Saudi Arabia., ALYounes B; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Saudi Human Genome Project, Riyadh, Saudi Arabia., Binhumaid FS; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Saudi Human Genome Project, Riyadh, Saudi Arabia., ALOtaibi AB; Saudi Human Genome Project, Riyadh, Saudi Arabia.; King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia., Altamimi AS; Saudi Human Genome Project, Riyadh, Saudi Arabia.; King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia., Alamer FH; Saudi Human Genome Project, Riyadh, Saudi Arabia.; King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia., Hashem M; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia., Abouelhoda M; Saudi Human Genome Project, Riyadh, Saudi Arabia., Monies D; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Saudi Human Genome Project, Riyadh, Saudi Arabia., Alkuraya FS; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. falkuraya@kfshrc.edu.sa.; Saudi Human Genome Project, Riyadh, Saudi Arabia. falkuraya@kfshrc.edu.sa.

Publikováno v: Human genetics [Hum Genet] 2016 Feb; Vol. 135 (2), pp. 193-200. Date of Electronic Publication: 2015 Dec 22.