Treatment patterns and outcomes in metastatic castration-resistant prostate cancer patients with and without somatic or germline alterations in homologous recombination repair genes

Autor: Olmos, D., Lorente, D., Alameda, D., Cattrini, C., Romero-Laorden, N., Lozano, R., Lopez-Casas, P.P., Jambrina, A., Capone, C., Vanden Broecke, A.M., Trevisan, M., Van Sanden, S., Jürgens, A., Herrera-Imbroda, B., Castro, E.

Publikováno v: In Annals of Oncology May 2024 35(5):458-472

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Autor: Perez C., Botta C., Zabaleta A., Puig N., Cedena M. -T., Goicoechea I., Alameda D., Jose-Eneriz E. S., Merino J., Rodriguez-Otero P., Maia C., Alignani D., Maiso P., Manrique I., Lara-Astiaso D., Vilas-Zornoza A., Sarvide S., Riillo C., Rossi M., Rosinol L., Oriol A., Blanchard M. -J., Rios R., Sureda A., Martin J., Martinez R., Bargay J., de la Rubia J., Hernandez M. -T., Martinez-Lopez J., Orfao A., Agirre X., Prosper F., Mateos M. -V., Lahuerta J. -J., Blade J., San-Miguel J. F., Paiva B., Espinosa M. C., Zamudio J. L. G., Herranz E. R., Tamayo R. R., Sanchez J. M., Bernal L. P., Rodriguez A. P. G., Garcia M. E. G., Mayol A. S., Lleonart J. B., Suarez A., Garcia M. T. H., Gaisan C. M., Ruiz B. H., Montero F. C., de Miguel Llorente D., Ramos F. S., Garcia A. I., Manteca M. M., Martin J. M. H., Barrigon F. E., Frade J. G., de Coca A. G., Franco C. A., Gomez J. L., Perez E. C., Creixenti J. B., Balari A. M. S., Montes Y. G., Teigell L. E., Guinon A. G., Monreal E. A., Campos J. A. S., Tutusaus J. M. M., Rocafiguera A. O., Gorrochategui M. G., Mesa M. G., Silva C. C., Perez M. S. G., Loureiro A. D., Sanchez J. A. M., Irazu M. J. N., Parraga F. J. P., Palacios J. J. L., Barahona P. B., Rodriguez C. E., Rivas J. A. H., de Oteyza J. P., del Barrio R. I., de la Guia A. L., Amor A. A., Pareja E. P., Castello I. K., Rodriguez M. J. B., Martinez R. M., Grau R. R., Mesa E. G., Sainz E. R., de Arriba F., Jimenez J. M. M., Romera M., Cardoso F. P., Perez J. M. A., Pomposo M. P., Persona E. P., Casasus A. I. T., Garcia P. R., Ramos I. J., Lor M. B. V., Garcia P. L. F., Chamorro C. M.

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Blood
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

Granulocytic myeloid-derived suppressor cells (G-MDSCs) promote tumor growth and immunosuppression in multiple myeloma (MM). However, their phenotype is not well established for accurate monitoring or clinical translation. We aimed to provide the phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57c4b837fce8eddbe3294a53b97e516
https://doi.org/10.1182/blood.2019004537

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard and high risk myeloma

Autor: Goicoechea I, Puig N, Cedena MT, Burgos L, Cordón L, Vidriales MB, Flores-Montero J, Gutierrez NC, Calasanz MJ, Martin Ramos ML, Lara-Astiaso D, Vilas-Zornoza A, Alignani D, Rodriguez I, Sarvide S, Alameda D, Garcés JJG, Rodriguez S, Fresquet V, Celay J, Garcia-Sanz R, Martinez-Lopez J, Oriol A, Rios R, Martin-Sanchez J, Martinez-Martinez R, Sarra J, Hernandez MT, de la Rubia J, Krsnik I, Moraleda JM, Palomera L, Bargay J, Martinez-Climent JA, Orfao A, Rosiñol L, Mateos MV, Lahuerta JJ, Blade J, San Miguel J, Paiva B

Publikováno v: Blood
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Patients with multiple myeloma (MM) carrying high-risk cytogenetic abnormalities (CA) have inferior outcome despite achieving similar complete response (CR) rates when compared to cases with standard-risk CA. This questions the legitimacy of CR as tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::662afeb5374b7f68370e2620b1ad0a33
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=13310

YES1 drives lung cancer growth and progression and predicts sensitivity to dasatinib

Autor: Garmendia, I. (Irati), Pajares, M.J. (María José), Hermida-Prado, F. (Francisco), Ajona, D. (Daniel), Bertolo, C. (Cristina), Lavín, A. (Amaya), Remirez, A. (Ana), Valencia, K. (Karmele), Moreno, H. (Haritz), Ferrer, I. (Irene), Behrens, C. (C.), Cuadrado, M. (Myriam), Paz-Ares, L. (Luis), Bustelo, X.R. (Xose R.), Gil-Bazo, I. (Ignacio), Alameda, D. (Daniel), Lecanda, F. (Fernando), Calvo-González, A. (Alfonso), Felip, E. (Enriqueta), Sanchez-Cespedes, M. (Montserrat), Wistuba, I.I. (Ignacio I.), Granda-Díaz, R. (Rocío), Rodrigo, J.P. (Juan P.), García-Pedrero, J.M. (Juana M.), Pio, R. (Rubén), Montuenga-Badia, L.M. (Luis M.), Agorreta, J. (Jackeline)

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

Rationale: The characterization of new genetic alterations is essential to assign effective personalized therapies in non–small cell lung cancer (NSCLC). Furthermore, finding stratification biomarkers is essential for successful personalized therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::523754cc92a7e666cd076579a832838d
https://hdl.handle.net/10171/63276

590P PRORADIUM: Prospective analysis of the impact of germline mutations in homologous recombination (HR) genes on the response to radium-223 for metastatic castration resistant prostate cancer (mCRPC)

Autor: Castro, E., Lozano Mejorada, R., Medina, A., Giorgi, U., Romero Laorden, N., Conteduca, V., De Velasco, G., Alameda, D., Sanz, A., Puente, J., Gonzalez del Alba, A., Borrega, P., Villa Guzmán, J.C., Fernández-Parra, E.M., Rodriguez-Vida, A., Chirivella, I., Vazquez, F., Morales Barrera, R., Lorente, D., Olmos, D.

Publikováno v: In Annals of Oncology September 2021 32 Supplement 5:S638-S639