Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alaknanda Adwal"'
Autor:
Krzysztof M. Mrozik, Chee M. Cheong, Duncan R. Hewett, Jacqueline E. Noll, Khatora S. Opperman, Alaknanda Adwal, Darryl L. Russell, Orest W. Blaschuk, Kate Vandyke, Andrew C. W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 6, Pp 339-353 (2020)
Abstract N‐cadherin is a homophilic cell‐cell adhesion molecule that plays a critical role in maintaining vascular stability and modulating endothelial barrier permeability. Pre‐clinical studies have shown that the N‐cadherin antagonist pepti
Externí odkaz:
https://doaj.org/article/c6826197d1b54a479b78471d9ab82b5d
Autor:
Kathryn A. Palasis, Noor A. Lokman, Bryden C. Quirk, Alaknanda Adwal, Loretta Scolaro, Weikun Huang, Carmela Ricciardelli, Martin K. Oehler, Robert A. McLaughlin, Andrew D. Abell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10844 (2021)
Local activation of an anti-cancer drug when and where needed can improve selectivity and reduce undesirable side effects. Photoswitchable drugs can be selectively switched between active and inactive states by illumination with light; however, the c
Externí odkaz:
https://doaj.org/article/38ae3d5432854cdaa9186ac918371334
Autor:
Andrew D. Abell, Sabrina Heng, Mark R. Hutchinson, Alaknanda Adwal, Philipp Reineck, Brant C. Gibson, Xiaozhou Zhang, Jinxin V. Pei
Publikováno v:
Chemistry – A European Journal. 25:854-862
Sabrina Heng, Xiaozhou Zhang, Jinxin Pei, Alaknanda Adwal, Philipp Reineck, Brant C. Gibson, Mark R. Hutchinson and Andrew D. Abell
Autor:
Andrew D. Abell, Loretta Scolaro, Carmela Ricciardelli, Noor A. Lokman, Weikun Huang, Alaknanda Adwal, Bryden C. Quirk, Martin K. Oehler, Robert A. McLaughlin, Kathryn A. Palasis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10844, p 10844 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Refereed/Peer-reviewed Local activation of an anti-cancer drug when and where needed can improve selectivity and reduce undesirable side effects. Photoswitchable drugs can be selectively switched between active and inactive states by illumination wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9d719432aaaa0f08dd7560bf9d99a0
https://hdl.handle.net/11541.2/25973
https://hdl.handle.net/11541.2/25973
Autor:
Emarene Kalaw, David F. Callen, Reshma Shakya, Malcolm Lim, Sunil R. Lakhani, Alaknanda Adwal, Lucinda D Taege, Amy E. McCart Reed, Jodi M. Saunus, Priyakshi Kalita-de Croft
Publikováno v:
Life Science Alliance
Engaging the immunoproteasome helps maintain proteostasis during TNBC development, but ultimately leads to increased immune visibility and favorable prognosis. Assessing i-proteasome expression could augment the prognostic and/or predictive value of
Autor:
Alaknanda Adwal, Brendan J Houston, Elodie Desroziers, Amy Winship, Elizabeth G. Bromfield, Dulama Richani, Tessa Lord, Macarena B. Gonzalez, Gulfam Ahmad, Jacqueline F. Donoghue, Jacinta H. Martin
Publikováno v:
Reproduction, Fertility and Development. 32:637
The 2019 meeting of the Society for Reproductive Biology (SRB) provided a platform for the dissemination of new knowledge and innovations to improve reproductive health in humans, enhance animal breeding efficiency and understand the effect of the en
Autor:
Sabrina, Heng, Xiaozhou, Zhang, Jinxin, Pei, Alaknanda, Adwal, Philipp, Reineck, Brant C, Gibson, Mark R, Hutchinson, Andrew D, Abell
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(3)
A new spiropyran-based stimuli-responsive delivery system is fabricated. It encapsulates and then releases an extraneous compound in response to elevated levels of Zn
Publikováno v:
Bioorganicmedicinal chemistry. 25(19)
A series of azobenzene-containing peptidic boronate esters was prepared and the activity of the thermally adapted states (TAS), enriched in trans isomer, and the photostationary states (PSS), enriched in cis isomer, for each compound were evaluated a
Publikováno v:
ACS medicinal chemistry letters. 7(12)
Proteasome is a large proteinase complex that degrades proteins via its three catalytic activities. Among these activities, the "chymotrypsin-like" activity has emerged as the focus of drug discovery in cancer therapy. Here, we report new peptidomime
Autor:
Gelareh Farshid, Mark Clayer, Susan J. Neuhaus, Alexander H. Staudacher, Kathleen I. Pishas, Alaknanda Adwal, David F. Callen
Publikováno v:
Scientific Reports
There is an imperious need for the development of novel therapeutics for the treatment of Ewing sarcoma, the second most prevalent solid bone tumour observed in children and young adolescents. Recently, a 4-nitrobenzofuroxan derivative, XI-006 (NSC20