Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Alakesh, Bera"'
Autor:
Yong Li, Steven A Rosenberg, Paul F Robbins, Zhiya Yu, Maria Parkhurst, Billel Gasmi, Nikolaos Zacharakis, Todd D Prickett, Jared J Gartner, Sri Krishna, Stephanie L Goff, Satyajit Ray, Frank J Lowery, Sivasish Sindiri, Alakesh Bera, Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Lior Levy, Tiffany Benzine, Robert V Masi, Rafiqul Islam
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Tumor-infiltrating lymphocytes (TILs) targeting neoantigens can effectively treat a selected set of metastatic solid cancers. However, harnessing TILs for cancer treatments remains challenging because neoantigen-reactive T cells are often
Externí odkaz:
https://doaj.org/article/f685ba7746d3429ab6dd6d6e8a83fc10
Autor:
Steven A Rosenberg, Paul Robbins, Biman Paria, Jared J Gartner, Sri Krishna, Satyajit Ray, Rami Yossef, Victoria Hill, Frank J Lowery, Praveen D Chatani, Neilesh B Parikh, Kyle J Hitscherich, Maria Florentin, Alakesh Bera, Maria Parkhust
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Cellular immunotherapies using autologous tumor-infiltrating lymphocytes (TIL) can induce durable regression of epithelial cancers in selected patients with treatment-refractory metastatic disease. As the genetic engineering of T cells wit
Externí odkaz:
https://doaj.org/article/cbbdaffbcb90479ea2c903c47528272b
Autor:
Hung Caohuy, Ofer Eidelman, Tinghua Chen, Shufeng Liu, Qingfeng Yang, Alakesh Bera, Nathan I. Walton, Tony T. Wang, Harvey B. Pollard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract To initiate SARS-CoV-2 infection, the Receptor Binding Domain (RBD) on the viral spike protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2-expressing cells. We hypothesized that cardiac glycoside drugs might
Externí odkaz:
https://doaj.org/article/2ea2813bebb54bb3b57a27ab3d2f0753
Autor:
Meera Srivastava, Alakesh Bera, Ofer Eidelman, Minh B. Tran, Catherine Jozwik, Mirta Glasman, Ximena Leighton, Hung Caohuy, Harvey B. Pollard
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8818 (2023)
Annexin A7/ANXA7 is a calcium-dependent membrane fusion protein with tumor suppressor gene (TSG) properties, which is located on chromosome 10q21 and is thought to function in the regulation of calcium homeostasis and tumorigenesis. However, whether
Externí odkaz:
https://doaj.org/article/8909e9198dc642e48842c00e558fc3eb
Autor:
Othello Del Rosario, Karthik Suresh, Medha Kallem, Gayatri Singh, Anika Shah, Linda Zheng, Xin Yun, Nicolas M. Philip, Nirupama Putcha, Marni B. McClure, Haiyang Jiang, Franco D’Alessio, Meera Srivastava, Alakesh Bera, Larissa A. Shimoda, Michael Merchant, Madhavi J. Rane, Carolyn E. Machamer, Jason Mock, Robert Hagan, Abigail L. Koch, Naresh M. Punjabi, Todd M. Kolb, Mahendra Damarla
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L700-L711
We have previously identified mitogen-activated protein kinase-activated protein kinase 2 (MK2) is required for caspase-3 nuclear translocation in the execution of apoptosis; however, little is known of the underlying mechanisms. Therefore, we sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48de92817e39ab7746442bb9e635edfa
https://doi.org/10.1152/ajplung.00340.2022
https://doi.org/10.1152/ajplung.00340.2022
Autor:
Karthik Suresh, Othello Del Rosario, Medha Kallem, Gayatri Singh, Anika Shah, Linda Zheng, Xin Yun, Nicolas M. Philip, Nirupama Putcha, Marni B. McClure, Haiyang Jiang, Franco D’Alessio, Meera Srivastava, Alakesh Bera, Larissa A. Shimoda, Michael Merchant, Madhavi J. Rane, Carolyn E. Machamer, Jason Mock, Robert Hagan, Abigail L. Koch, Naresh M. Punjabi, Todd M. Kolb, Mahendra Damarla
Publikováno v:
Physiological Genomics. 55:168-178
MK2, known to promote caspase-3 nuclear translocation in the execution of apoptosis, is reduced in non-small cell lung cancer cells. In adenocarcinomas of patients, higher MK2 expression is associated with early-stage disease, better clinical respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4858e57e9d5950f2a285f4ab23fa97ee
https://doi.org/10.1152/physiolgenomics.00155.2022
https://doi.org/10.1152/physiolgenomics.00155.2022
Autor:
Alakesh Bera, Madhan Subramanian, John Karaian, Michael Eklund, Surya Radhakrishnan, Nahbuma Gana, Stephen Rothwell, Harvey Pollard, Hai Hu, Craig D Shriver, Meera Srivastava
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242141 (2020)
Breast Cancer is the most common form of cancer in women worldwide, impacting nearly 2.1 million women each year. Identification of new biomarkers could be key for early diagnosis and detection. Vitronectin, a glycoprotein that is abundantly found in
Externí odkaz:
https://doaj.org/article/1c9493b3c3b74d10ac7f3e04c9d0f774
Autor:
Alakesh Bera, Sajal Biring
Publikováno v:
Biochemistry and Biophysics Reports, Vol 14, Iss C, Pp 114-124 (2018)
Binding of recombinant prion protein with small highly structured RNAs, prokaryotic and eukaryotic prion protein mRNA pseudoknots, tRNA and polyA has been studied by the change in fluorescence anisotropy of the intrinsic tryptophan groups of the prot
Externí odkaz:
https://doaj.org/article/d72c6d4509cb45018bc75828e022afb0
Autor:
Sanghyun P. Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger, Frank J. Lowery, Maria R. Parkhurst, Lien T. Ngo, Satyajit Ray, Yong F. Li, Victoria Hill, Maria Florentin, Robert V. Masi, Biman C. Paria, Noam Levin, Alakesh Bera, Elizabeth A. Hedges, Agnes Choi, Praveen D. Chatani, Anup Y. Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D. Prickett, Li Jia, Jonathan M. Hernandez, Chuong D. Hoang, Paul F. Robbins, Stephanie L. Goff, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
Publikováno v:
Cancer Immunology Research. 10:932-946
Adoptive cellular therapy (ACT) targeting neoantigens can achieve durable clinical responses in patients with cancer. Most neoantigens arise from patient-specific mutations, requiring highly individualized treatments. To broaden the applicability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd7c2cf7704a11e5d74fd00ce2ec8d0
https://doi.org/10.1158/2326-6066.cir-22-0040
https://doi.org/10.1158/2326-6066.cir-22-0040
Autor:
Steven A. Rosenberg, James C. Yang, Richard M. Sherry, Stephanie L. Goff, Paul F. Robbins, Chuong D. Hoang, Jonathan M. Hernandez, Li Jia, Todd D. Prickett, Zhili Zheng, Yong-Chen Lu, Samantha Seitter, Shoshana Levi, Anup Y. Parikh, Praveen D. Chatani, Agnes Choi, Elizabeth A. Hedges, Alakesh Bera, Noam Levin, Biman C. Paria, Robert V. Masi, Maria Florentin, Victoria Hill, Yong F. Li, Satyajit Ray, Lien T. Ngo, Maria R. Parkhurst, Frank J. Lowery, Drew C. Deniger, Parisa Malekzadeh, Sivasish Sindiri, Jared J. Gartner, Billel Gasmi, Zhiya Yu, Sri Krishna, Nikolaos Zacharakis, Nolan R. Vale, Sanghyun P. Kim
Supplementary Figure from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e3f8c006b4d5783eb104fc14a96821
https://doi.org/10.1158/2326-6066.22545620.v1
https://doi.org/10.1158/2326-6066.22545620.v1
