Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alaina Kaiser"'
Autor:
David Dodds, Jeffrey L. Bose, Ming-De Deng, Gilles R. Dubé, Trudy H. Grossman, Alaina Kaiser, Kashmira Kulkarni, Roger Leger, Sara Mootien-Boyd, Azim Munivar, Julia Oh, Matthew Pestrak, Komal Rajpura, Alexander P. Tikhonov, Traci Turecek, Travis Whitfill
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Using live microbes as therapeutic candidates is a strategy that has gained traction across multiple therapeutic areas. In the skin, commensal microorganisms play a crucial role in maintaining skin barrier function, homeostasis, and cutaneou
Externí odkaz:
https://doaj.org/article/ba1d4abd99a34cf9a5fdc6d24226e084
Autor:
Qiong Xue, Emily Bettini, Patrick Paczkowski, Colin Ng, Alaina Kaiser, Timothy McConnell, Olja Kodrasi, Máire F. Quigley, James Heath, Rong Fan, Sean Mackay, Mark E. Dudley, Sadik H. Kassim, Jing Zhou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-16 (2017)
Abstract Background It remains challenging to characterize the functional attributes of chimeric antigen receptor (CAR)-engineered T cell product targeting CD19 related to potency and immunotoxicity ex vivo, despite promising in vivo efficacy in pati
Externí odkaz:
https://doaj.org/article/ad391b0cd0634de0af9c0fb1b8b1b2e4
Autor:
Jing Zhou, Alaina Kaiser, Colin Ng, Rachel Karcher, Tim McConnell, Patrick Paczkowski, Cristina Fernandez, Min Zhang, Sean Mackay, Moriya Tsuji
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 7, Pp 1625-1629 (2017)
Malaria is a severe infectious disease with relatively high mortality, thus having been a scourge of humanity. There are a few candidate malaria vaccines that have shown a protective efficacy in humans against malaria. One of the candidate human mala
Externí odkaz:
https://doaj.org/article/e98de273ed19452fa7b4d4ac5281af2c
Publikováno v:
Cancer Research. 82:3919-3919
Proteomics have the potential to transform biomarker discovery, diagnostics, and personalized medicine as it provides functional and actionable information linked to disease phenotypes. However, mass spectrometry (MS) – based proteomics has not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db85a8c28f2f2c4b7fde797afc97c88e
https://doi.org/10.1158/1538-7445.am2022-3919
https://doi.org/10.1158/1538-7445.am2022-3919
Publikováno v:
Journal of Clinical Oncology. 40:e15010-e15010
e15010 Background: Circulating biomarkers have the potential to detect cancer in its earliest stages and monitor patients in remission. The integration of proteogenomics in circulating biomarkers may transform the molecular diagnostics of cancer and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2bb57d3a62c50ccf5d7cd5297046d8
https://doi.org/10.1200/jco.2022.40.16_suppl.e15010
https://doi.org/10.1200/jco.2022.40.16_suppl.e15010
Autor:
Jeffrey L. Bose, Sara Mootien-Boyd, Alaina Kaiser, Matthew Pestrak, Ming-De Dong, Roger Leger, Trudy H. Grossman, Traci Turecek, Travis Whitfill, Azim Munivar, Gilles R. Dubé, Kashmira Kulkarni, Julia Oh, Alexander P. Tikhonov, Komal Rajpura, David R. Dodds
Publikováno v:
mSphere
mSphere, Vol 5, Iss 3 (2020)
mSphere, Vol 5, Iss 3, p e00360-20 (2020)
mSphere, Vol 5, Iss 3 (2020)
mSphere, Vol 5, Iss 3, p e00360-20 (2020)
The skin microbiome is rich in opportunities for novel therapeutics for skin diseases, and synthetic biology offers the advantage of providing novel functionality or therapeutic benefit to live biotherapeutic products. The development of novel bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a3cdfe73e7b453cbeeada3a9cf92e9
http://europepmc.org/articles/PMC7289707
http://europepmc.org/articles/PMC7289707
Autor:
Alaina Kaiser, Brianna Flynn, Steven A. Rosenberg, James N. Kochenderfer, Kevin Morse, Adrian Bot, Yueh-wei Shen, John J. Rossi, Sean Mackay, Colin Ng, Tom Cain, Patrick Paczkowski, Rong Fan, James R. Heath, Kyle Gallatin, Jing Zhou
Publikováno v:
Blood
After treatment with chimeric antigen receptor (CAR) T cells, interleukin-15 (IL-15) elevation and CAR T-cell expansion are associated with non-Hodgkin lymphoma (NHL) outcomes. However, the association of preinfusion CAR product T-cell functionality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7066ae05b1c417a0f8474267c89b3f
https://doi.org/10.1182/blood-2018-01-828343
https://doi.org/10.1182/blood-2018-01-828343
Publikováno v:
Cancer Research. 81:19-19
Changes in transcript levels detected by transcriptome profiling have been widely used as a surrogate for proteomics. However, recent studies have shown accumulating evidence that phenotypes of diseases that show correlations with protein levels cann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3260cc190c2f92b42df2c74aa7d468
https://doi.org/10.1158/1538-7445.am2021-19
https://doi.org/10.1158/1538-7445.am2021-19
Autor:
Alaina Kaiser, Cristina Fernandez, Colin Ng, Jing Zhou, Patrick Paczkowski, Timothy McConnell, Sean Mackay, Moriya Tsuji, Rachel Karcher, Min Zhang
Publikováno v:
Human Vaccines & Immunotherapeutics. 13:1625-1629
Malaria is a severe infectious disease with relatively high mortality, thus having been a scourge of humanity. There are a few candidate malaria vaccines that have shown a protective efficacy in humans against malaria. One of the candidate human mala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0123ef7afbe549f2e9c053d2c8584fb2
https://doi.org/10.1080/21645515.2017.1304333
https://doi.org/10.1080/21645515.2017.1304333
Publikováno v:
Journal of Clinical Oncology. 39:e15019-e15019
e15019 Background: Liquid biopsy has evolved to be an important method complementary to tissue biopsy. It is not only non-invasive, but also has the potential to detect cancer in its earliest stages and monitor patients in remission. The integration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b58c4bd03815c3e800f7deb5cd36277
https://doi.org/10.1200/jco.2021.39.15_suppl.e15019
https://doi.org/10.1200/jco.2021.39.15_suppl.e15019