Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alaina K. Natoli"'
Autor:
Brian G. Drew, Andrew L. Carey, Alaina K. Natoli, Melissa F. Formosa, Donna Vizi, Medini Reddy-Luthmoodoo, Jacquelyn M. Weir, Christopher K. Barlow, Gerrit van Hall, Peter J. Meikle, Stephen J. Duffy, Bronwyn A. Kingwell
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 3, Pp 572-581 (2011)
We recently demonstrated that reconstituted high-density lipoprotein (rHDL) modulates glucose metabolism in humans via both AMP-activated protein kinase (AMPK) in muscle and by increasing plasma insulin. Given the key roles of both AMPK and insulin i
Externí odkaz:
https://doaj.org/article/ce166b01cfbd4c24950c9e5b1499a216
Autor:
Kevin D. Croft, Stephen J. Duffy, Alaina K. Natoli, Anthony M. Dart, Bronwyn A. Kingwell, Geoffrey Cox, Hans G. Schneider, Jenny Starr, William Chan
Publikováno v:
Journal of Vascular Surgery. 70:1564-1575
The cause of perioperative myocardial infarction (PMI) is postulated to involve hemodynamic stress or coronary plaque destabilization. We aimed to evaluate perioperative factors in patients with peripheral artery disease (PAD) undergoing major vascul
Autor:
Andrew L Carey, Camilla Vorlander, Medini Reddy-Luthmoodoo, Alaina K Natoli, Melissa F Formosa, David A Bertovic, Mitchell J Anderson, Stephen J Duffy, Bronwyn A Kingwell
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91997 (2014)
Brown adipose tissue (BAT) is a potential therapeutic target to reverse obesity. The purpose of this study was to determine whether primary precursor cells isolated from human adult subcutaneous white adipose tissue (WAT) can be induced to differenti
Externí odkaz:
https://doaj.org/article/3bb7cdd4f2a34a4aa34cf3ad31520729
Autor:
Brian G. Drew, Bronwyn A. Kingwell, Graeme I. Lancaster, Svetlana A Didichenko, Andrew L. Siebel, Mina Khalaji, Medini Reddy, Sarah E Heywood, Alexei V Navdaev, A. Richart, Andrew L. Carey, Alaina K. Natoli, Andrew J. Murphy
Publikováno v:
Circulation research. 127(11)
Rationale: Decades of research have examined immune-modulatory strategies to protect the heart after an acute myocardial infarction and prevent progression to heart failure but have failed to translate to clinical benefit. Objective: To determine ant
Autor:
Si Khiang Trinh, Gerrit van Hall, Andrew L. Carey, Piyushkumar A. Mundra, Stephen J. Duffy, Andrew L. Siebel, Bronwyn A. Kingwell, Melissa F. Formosa, Kevin Huynh, Jan Johansson, Kerry-Anne Rye, Chiara Dalla-Man, Allan Gordon, Jim D. Otvos, Alaina K. Natoli, Medini Reddy-Luthmoodoo, Dmitri Sviridov, Claudio Cobelli, Philip J. Barter, Norman C.W. Wong, Anmar A. Khan, Peter J. Meikle
Publikováno v:
Metabolism. 65:904-914
Aims High-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I) can modulate glucose metabolism through multiple mechanisms. This study determined the effects of a novel bromodomain and extra-terminal (BET) inhibitor (RVX-208) and putative apoA-I
Autor:
Medini Reddy-Luthmoodoo, Alaina K. Natoli, Dmitri Sviridov, Andrew L. Siebel, Felicia Y. T. Yap, Josephine M. Forbes, Chek Ing Kiu Weber, Georgina Meneses-Lorente, Cyrille Maugeais, Andrew L. Carey, Bronwyn A. Kingwell
Publikováno v:
Circulation Research. 113:167-175
Rationale: High-density lipoprotein cholesterol elevation via cholesteryl ester transfer protein (CETP) inhibition represents a novel therapy for atherosclerosis, which also may have relevance for type 2 diabetes mellitus. Objective: The current stud
Autor:
David W. Dunstan, Alaina K. Natoli, Celine Latouche, Neville Owen, Bronwyn A. Kingwell, Audrey Bergouignan, Sarah E Heywood, Medini Reddy-Luthmoodoo, Megan S. Grace
Publikováno v:
Scientific Reports
Epidemiological studies have observed associations between frequent interruptions of sitting time with physical activity bouts and beneficial metabolic outcomes, even in individuals who regularly exercise. Frequent interruptions to prolonged sitting
Autor:
James A. Armitage, Celine Latouche, Medini Reddy-Luthmoodoo, Alaina K. Natoli, Sarah E Heywood, Bronwyn A. Kingwell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155108 (2016)
PLoS ONE, Vol 11, Iss 5, p e0155108 (2016)
Background The regulation of microRNAs (miRNAs) at different stages of the progression of type 2 diabetes mellitus (T2DM) and their role in glucose homeostasis was investigated. Methods Microarrays were used to assess miRNA expression in skeletal mus
Publikováno v:
Hypertension. 67
Autor:
Andris H. Ellims, David M. Kaye, Andrew J. Taylor, Alaina K. Natoli, Stephen J. Duffy, Anthony M. Dart, Kevin D. Croft, Chiew Wong, William Chan, Trevor A. Mori, Lisa Lefkovits, Bronwyn A. Kingwell
Publikováno v:
Circulation: Cardiovascular Interventions. 5:270-278
Background— Experimental studies suggest that deferoxamine (DFO) limits the generation of reactive oxygen species by chelating redox-active iron and thereby may reduce ischemia-reperfusion injury and myocardial infarct (MI) size. We investigated wh