Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alaina H Willet"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010987 (2023)
Coupling cell wall expansion with cell growth is a universal challenge faced by walled organisms. Mutations in Schizosaccharomyces pombe css1, which encodes a PM inositol phosphosphingolipid phospholipase C, prevent cell wall expansion but not synthe
Externí odkaz:
https://doaj.org/article/7e1fb22ce6324b87ab7b109937d4355e
Myosin-1s are monomeric actin-based motors that function at membranes. Myo1 is the single myosin-1 isoform inSchizosaccharomyces pombethat works redundantly with Wsp1-Vrp1 to activate the Arp2/3 complex for endocytosis. Here, we identified Ank1 as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60efde0325c8e90ec21694ebc786d37c
https://doi.org/10.1101/2023.04.26.538419
https://doi.org/10.1101/2023.04.26.538419
Autor:
Zachary C. Elmore, Rachel H. Roberts-Galbraith, Alaina H. Willet, Rahul Bhattacharjee, Liping Ren, Sierra N. Cullati, Janel R. Beckley, Alyssa E. Johnson, Kathleen L. Gould, Jun-Song Chen, Maya G. Igarashi
Publikováno v:
J Cell Sci
The F-BAR protein Imp2 is an important contributor to cytokinesis in the fission yeast Schizosaccharomyces pombe. Because cell cycle-regulated phosphorylation of the central intrinsically disordered region (IDR) of the Imp2 paralog Cdc15 controls Cdc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41de648745a10d9d2e6b901d44d08d3e
https://europepmc.org/articles/PMC8435286/
https://europepmc.org/articles/PMC8435286/
Autor:
HannahSofia T. Brown, Alaina H. Willet, Joshua M. Evers, Chloe E. Snider, Kathleen L. Gould, Jun-Song Chen
Publikováno v:
Journal of Cell Science.
Phosphoinositides (PIPs) are a dynamic family of lipids that execute diverse roles in cell biology. PIP levels are regulated by numerous enzymes, but our understanding of how these enzymes are controlled in space and time is incomplete. One role of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62c55f44a162ea09295972074046589
https://doi.org/10.1242/jcs.247973
https://doi.org/10.1242/jcs.247973
Publikováno v:
Molecular Biology of the Cell
In Schizosaccharomyces pombe, loss of the plasma membrane PI4-kinase scaffold Efr3 leads to sliding of the cytokinetic ring (CR) away from the cell center during anaphase, implicating phosphoinositides (PIPs) in CR anchoring. However, whether other P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793393c1c9c49c0941b91e4ddd5d0da
http://europepmc.org/articles/PMC6249800
http://europepmc.org/articles/PMC6249800
Autor:
Kathleen L. Gould, Alaina H. Willet, Chloe E. Snider, Marija Zanic, Goker Arpag, Jun-Song Chen
Publikováno v:
The Journal of Cell Biology
Altering phosphoinositide composition through deletion of efr3, a PI4 kinase scaffold, results in type V myosin-dependent cytokinetic ring sliding in Schizosaccharomyces pombe. Membrane-binding proteins contribute to ring anchoring to resist perpendi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4137932d0b984aee77f86533aab8a736
https://doi.org/10.1083/jcb.201705070
https://doi.org/10.1083/jcb.201705070
Autor:
Melanie D. Ohi, Scott E. Collier, Lauren P. Jackson, Alaina H. Willet, Nathan A. McDonald, Chloe E. Snider, Kathleen L. Gould, Mintu Chandra
Publikováno v:
Cell Reports. 33:108526
Many eukaryotes assemble an actin- and myosin-based cytokinetic ring (CR) on the plasma membrane (PM) for cell division, but how it is anchored there remains unclear. In Schizosaccharomyces pombe, the F-BAR protein Cdc15 links the PM via its F-BAR do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d706d5fbaab71c22f21ff7b65645553
https://doi.org/10.1016/j.celrep.2020.108526
https://doi.org/10.1016/j.celrep.2020.108526
Publikováno v:
Current biology : CB. 29(6)
Summary In animals and fungi, cytokinesis is facilitated by the constriction of an actomyosin contractile ring (CR) [ 1 ]. In Schizosaccharomyces pombe, the CR forms mid-cell during mitosis from clusters of proteins at the medial cell cortex called n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b78377d5990136e4dfea124b9a84f0a
https://pubmed.ncbi.nlm.nih.gov/30853434
https://pubmed.ncbi.nlm.nih.gov/30853434
Autor:
Janel R. Beckley, Jürg Bähler, Danny A. Bitton, Nathan A. McDonald, Zachary C. Elmore, Nicholas Rhind, Sylvia J Jang, Kathleen L. Gould, MariaSanta C. Mangione, Nicole Rachfall, Michael A. Jensen, Alaina H. Willet, Anna Feoktistova, Christine M. Jones, Liping Ren, Rodrigo X. Guillen, Jun-Song Chen
Publikováno v:
G3: Genes|Genomes|Genetics
Many fundamental biological processes are studied using the fission yeast, Schizosaccharomyces pombe. Here we report the construction of a set of 281 haploid gene deletion strains covering many previously uncharacterized genes. This collection of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067894de5cf9cb1371121db80581c917
https://doi.org/10.1534/g3.114.015701
https://doi.org/10.1534/g3.114.015701
Autor:
Nathan A. McDonald, Michelle A. Baird, Michael W. Davidson, Alaina H. Willet, Kathleen L. Gould, John R. Allen, K. Adam Bohnert
Publikováno v:
The Journal of Cell Biology
Cdc15 contributes to contractile ring formation and cytokinesis by recruiting the formin Cdc12, which defines a novel cytokinetic function for an F-BAR domain.
In Schizosaccharomyces pombe, cytokinesis requires the assembly and constriction of a
In Schizosaccharomyces pombe, cytokinesis requires the assembly and constriction of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63972051076c5490ff460b645dfe78a8
https://doi.org/10.1083/jcb.201411097
https://doi.org/10.1083/jcb.201411097