Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Alain Virion"'
Autor:
Nesrine Benfares, Virginie Belotte, Sédami Gnidehou, Martin Schlumberger, Alain Virion, Jean-Christophe Sabourin, Stanislas Morand, Renée Ohayon, Jean-Michel Bidart, Marie-Sophie Noël-Hudson, Corinne Dupuy, Diane Agnandji, Bernard Caillou, Monique Talbot, Rabii Ameziane El Hassani, Jacques Kaniewski
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G933-G942
The dual oxidase (Duox)2 flavoprotein is strongly expressed in the thyroid gland, where it plays a critical role in the synthesis of thyroid hormones by providing thyroperoxidase with H2O2. DUOX2 mRNA was recently detected by RT-PCR and in-situ hybri
Publikováno v:
European Journal of Biochemistry. 118:239-245
The respective role of iodide and of free diiodotyrosine on thyroid hormone synthesis (coupling reaction) has been analyzed under a variety of enzymatic and non-enzymatic conditions. The coupling reaction was studied either during the course of the i
Publikováno v:
European Journal of Biochemistry. 117:103-109
1 When thyroglobulin iodination by thyroid peroxidase or lactoperoxidase is studied with optimal concentrations of H2O2-generating system, thyroid hormone synthesis (coupling reaction) begins after a constant lag period which is independent of the co
Autor:
Corinne Dupuy, Michaelle Rakotomanga, Philippe M. Loiseau, Stanislas Morand, Alain Virion, Mohammad Pourshafie
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2409-2414
The 24-alkylated sterols have been shown previously to be absent in membranes of amphotericin B (AmB)-resistant Leishmania donovani promastigotes, suggesting that the S - adenosyl- l -methionine:C-24-Δ-sterol-methyltransferase (SCMT or ERG6) was not
Autor:
Jacques Kaniewski, Stanislas Morand, Renée Ohayon, Orquidea Filipe Dos Santos, Marie-Sophie Noel-Hudson, Alain Virion, Corinne Dupuy
Publikováno v:
Endocrinology. 144:567-574
The Duox2 flavoprotein is strongly expressed in the thyroid gland, where it plays a critical role in the synthesis of thyroid hormones likely by providing thyroperoxidase with H(2)O(2). A truncated DUOX2 mRNA was isolated from the rat thyroid cell li
Autor:
Alain Virion, Martin Schlumberger, Corinne Dupuy, Bernard Caillou, Monique Talbot, Ludovic Lacroix, Renée Ohayon, Jean-Michel Bidart, Maria Nocera, Danielle Dème
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:3351-3358
The large homolog of NADPH oxidase flavoprotein LNOX2, and probably LNOX1, are flavoproteins involved in the thyroid H2O2 generator. Western blot analysis of membrane proteins from normal human thyroid, using antipeptide antibodies, indicated that LN
Autor:
Danielle Dème, Corinne Dupuy, Marie-Sophie Noël-Hudson, Renée Ohayon, Alexander Valent, Alain Virion
Publikováno v:
Journal of Biological Chemistry. 274:37265-37269
Hydrogen peroxide is the final electron acceptor for the biosynthesis of thyroid hormone catalyzed by thyroperoxidase at the apical surface of thyrocytes. Pig and human thyroid plasma membrane contain a Ca2+-dependent NAD(P)H oxidase that generates H
Autor:
Alain Virion, Corinne Dupuy, Jacques Pommier, Renée Ohayon, Yves Gorin, Danielle Dème, Anne Marie Leseney
Publikováno v:
Biochemical Journal. 321:383-388
Pig thyroid plasma membranes contain a Ca(2+)-dependent NADPH:O2 oxidoreductase, the thyroid NADPH-dependent H2O2 generator. This provided the H2O2 for the peroxidase-catalysed synthesis of thyroid hormones. The effect of the tervalent arsenical, phe
Autor:
Danielle Dème, Renée Ohayon, Alain Virion, Corinne Dupuy, Anne Marie Leseney, Bernard Haye, Denise P. Carvalho, Yves Gorin, Jacques Pommier, Jacques Kaniewski
Publikováno v:
European Journal of Biochemistry. 240:807-814
The thyroid plasma membrane contains a Ca(2+)-regulated NADPH-dependent H2O2-generating system which provides H2O2 for the thyroid-peroxidase-catalyzed biosynthesis of thyroid hormones. The molecular nature of the membrane-associated electron transpo
Autor:
Denise P. Carvalho, Jacques Pommier, Odette Legue, Bernard Haye, Yves Gorin, Alain Virion, Corinne Dupuy
Publikováno v:
Endocrinology. 137:1007-1012
Hydrogen peroxide (H2O2) is an essential electron acceptor for thyroid peroxidase-catalyzed iodination and coupling reactions. In the presence of iodide, its production is a limiting step in thyroid hormone biosynthesis. Several studies have demonstr