Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Alain Valleix"'
Autor:
Emmanuel Godat, Jean Labarre, Christophe Junot, Alain Valleix, Yves Boulard, Hervé Desvaux, Olivier Delalande
Publikováno v:
FEBS Journal. 277:5086-5096
Cadmium is a heavy metal and a pollutant that can be found in large quantities in the environment from industrial waste. Its toxicity for living organisms could arise from its ability to alter thiol-containing cellular components. Glutathione is an a
Autor:
Sandra De Lamo Marin, Alain Wagner, Charles Mioskowski, Cedric Catala, Sreekantha Ratna Kumar, Alain Valleix
Publikováno v:
European Journal of Organic Chemistry. 2010:3985-3989
(2S,3R,4S)-4-Hydroxyisoleucine, which exhibits remarkable insulinotropic activity, is expected to be a potent drug to treat type II diabetes. We propose herein a four-step synthesis of the enantiopure natural product on the basis of successive Mannic
Publikováno v:
Synlett. 2008:2503-2507
The cross enyne metathesis reaction of propargylic fluoride (+)-12 with ethylene affords the enantioenriched 1,3-diene (+)-14 having fluorine-containing side chain at 2-position in good yield. Upon Diels-Alder reaction, followed by aromatization, thi
Publikováno v:
Synlett. 2008:268-272
Ionic liquids are remarkably suitable and clean media for performing nonenzymatic kinetic resolution (KR) of amines through enantioselective N-acetylation: high levels of selectivity were obtained with a large variety of amines at room temperature (u
Publikováno v:
Steroids. 69:461-471
A new time-resolved fluoroimmunoassay (TR-FIA) of testosterone in serum is described, using a biotinylated testosterone tracer, with a long spacer arm between biotin and testosterone, coupled to the C3 of the testosterone: a biotinylaminodecane carbo
Autor:
Stéphane Meunier, Charles Mioskowski, Alain Valleix, Jean Philippe Renault, Stéphanie Nowaczyk, Eric Saint-Aman, Marine Desage-El Murr, Thierry Le Gall, Didier Boquet, Frédéric Taran, Christophe Créminon, Serge Pin
Publikováno v:
ChemBioChem. 5:832-840
We present a new high-throughput screening method for the selection of powerful water-soluble antiradiation compounds. This method, which uses conventional immunoassay techniques, allowed the capacity of a given compound to protect thymidine from irr
Autor:
Frank Giton, Jean Fiet, Alain Bélanger, Hervé Galons, Alain Valleix, Jean Marie Villette, Philippe Boudou
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 81:85-94
We described a new, specific and easy to use radioimmunoassay (RIA) of estrone sulfate (E1S) in males. After synthesis of an E1S-6-(O-carboxymethyl) oxime hapten then coupling to BSA, we obtained a specific anti-E1S antiserum. Although the cross-reac
Autor:
Alain Wagner, Christophe Créminon, Alain Valleix, Stéphane Meunier, Charles Mioskowski, Jacques Grassi, Frédéric Taran, Cécile Gauchet, Barbara Mohar, Pierre-Yves Renard
Publikováno v:
Angewandte Chemie. 114:132-135
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2002, 67 (1), pp.146-153. ⟨10.1021/jo015836e⟩
Journal of Organic Chemistry, 2002, 67 (1), pp.146-153. ⟨10.1021/jo015836e⟩
Journal of Organic Chemistry, American Chemical Society, 2002, 67 (1), pp.146-153. ⟨10.1021/jo015836e⟩
Journal of Organic Chemistry, 2002, 67 (1), pp.146-153. ⟨10.1021/jo015836e⟩
Dinucleoside polyphosphates are ubiquitous compounds tightly involved in the regulation of a number of key biological processes. Hydrolysis-resistant analogues of Ap(3)A and Gp(3)G, two important members of that family of nucleotides, have been synth
Publikováno v:
European Journal of Organic Chemistry. 2001:3961-3964
The synthesis of three bifunctional 3-phenyl-3-(trifluoromethyl)diazirinyl building blocks is described. These compounds were designed for their potential chemical reactivity toward a wide range of functional groups occurring in proteins and small mo