Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Alain T. Sané"'
Autor:
Nickolas Auclair, Alain T. Sané, Léna Ahmarani, Nour-El-Houda Ould-Chikh, Nathalie Patey, Jean-François Beaulieu, Edgard Delvin, Schohraya Spahis, Emile Levy
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 9, Pp 100423- (2023)
Biallelic pathogenic variants of the Sar1b gene cause chylomicron retention disease (CRD) whose central phenotype is the inability to secrete chylomicrons. Patients with CRD experience numerous clinical symptoms such as gastrointestinal, hepatic, neu
Externí odkaz:
https://doaj.org/article/fac6eb6ad59e469280811c93cc3f46d2
Autor:
Nickolas Auclair, Alain T. Sané, Lena Ahmarani, Nathalie Patey, Jean-François Beaulieu, Noel Peretti, Schohraya Spahis, Emile Levy
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100085- (2021)
Chylomicron retention disease (CRD) is an autosomal recessive disorder associated with biallelic Sar1b mutations leading to defects in intracellular chylomicron (CM) trafficking and secretion. To date, a direct cause-effect relationship between CRD a
Externí odkaz:
https://doaj.org/article/ee8165d0dcfa4ef1b46a346787854c2c
Autor:
Mathilde Foisy-Sauvé, Lena Ahmarani, Edgard Delvin, Alain T. Sané, Schohraya Spahis, Emile Levy
Publikováno v:
Nutrients, Vol 12, Iss 4, p 1175 (2020)
Background. Metabolic Syndrome (MetS), a major worldwide concern for the public health system, refers to a cluster of key metabolic components, and represents a risk factor for diabetes and cardiovascular diseases. As oxidative stress (OxS) and infla
Externí odkaz:
https://doaj.org/article/fd17b2b480fa446da9186dc2b108c341
Publikováno v:
Antioxidants & Redox Signaling. 34:252-278
Significance: Cardiometabolic disorders (CMD) are composed of a plethora of metabolic dysfunctions such as dyslipidemia, nonalcoholic fatty liver disease, insulin resistance, and hypertension. The ...
Autor:
Thierry Ntimbane, Mathilde Foisy Sauvé, Alain Stintzi, Nathalie Patey, Francis Feldman, Edgard Delvin, Ramy El-Jalbout, Nour-El-Houda Ould-Chikh, Emile Levy, Lena Ahmarani, Mireille Koudoufio, Schohraya Spahis, Alain T. Sané
Publikováno v:
Biomedicines, Vol 9, Iss 1140, p 1140 (2021)
Biomedicines
Volume 9
Issue 9
Biomedicines
Volume 9
Issue 9
Background and Aims: The increasing prevalence and absence of effective global treatment for metabolic syndrome (MetS) are alarming given the potential progression to severe non-communicable disorders such as type 2 diabetes and nonalcoholic fatty li
Autor:
Emile Levy, Nickolas Auclair, Lena Ahmarani, Jean-François Beaulieu, Noël Peretti, Nathalie Patey, Schohraya Spahis, Alain T. Sané
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100085-(2021)
Journal of Lipid Research, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2021, 62, pp.100085. ⟨10.1016/j.jlr.2021.100085⟩
Journal of Lipid Research, Vol 62, Iss, Pp 100085-(2021)
International audience; Chylomicron retention disease (CRD) is an autosomal recessive disorder associated with biallelic Sar1b mutations leading to defects in intracellular chylomicron (CM) trafficking and secretion. To date, a direct cause-effect re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437c6d76490d2b00b616f9ab5275cf52
https://doi.org/10.1016/j.jlr.2021.100085
https://doi.org/10.1016/j.jlr.2021.100085
Autor:
Edgard Delvin, Schohraya Spahis, Alain T. Sané, Mathilde Foisy-Sauvé, Lena Ahmarani, Emile Levy
Publikováno v:
Nutrients, Vol 12, Iss 1175, p 1175 (2020)
Nutrients
Volume 12
Issue 4
Nutrients
Volume 12
Issue 4
Background. Metabolic Syndrome (MetS), a major worldwide concern for the public health system, refers to a cluster of key metabolic components, and represents a risk factor for diabetes and cardiovascular diseases. As oxidative stress (OxS) and infla
Autor:
Ernest G. Seidman, Emile Levy, Schohraya Spahis, Marie Laure Kleme, Alain T. Sané, Edgard Delvin, Noël Peretti, Colette Deslandres, Carole Garofalo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2017, 37 (12), pp.2243--2251. ⟨10.1161/ATVBAHA.117.310121⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2017, 37 (12), pp.2243--2251. ⟨10.1161/ATVBAHA.117.310121⟩
Background— Understanding the specific mechanisms of rare autosomal disorders has greatly expanded insights into the complex processes regulating intestinal fat transport. Sar1B GTPase is one of the critical proteins governing chylomicron secretion
Autor:
Nour Haddad, Edgard Delvin, Yves Desjardins, Jean-François Beaulieu, Eric Tremblay, Natalie Patey, Emile Levy, Denis Roy, Carole Garofalo, Pantea Rahmani Yeganeh, Devendra Amre, Alexandra Furtos, Alain T. Sané, Thibault V. Varin, André Marette, Marie Claude Denis
Publikováno v:
Clinical Science. 130:2217-2237
Diets rich in fruits and vegetables may reduce oxidative stress (OxS) and inflammation via several mechanisms. These beneficial effects may be due to their high polyphenol content. The aims of the present study are to evaluate the preventive and ther
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 60, Iss 10, Pp 1755-1764 (2019)
Journal of Lipid Research, Vol 60, Iss 10, Pp 1755-1764 (2019)
Genetic defects in SAR1B GTPase inhibit chylomicron (CM) trafficking to the Golgi and result in a huge intraenterocyte lipid accumulation with a failure to release CMs and liposoluble vitamins into the blood circulation. The central aim of this study