Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alain Stricker-Krongrad"'
Autor:
Anne Braun, Lilibeth Dofiles, Serge Rousselle, Luis Guerrero, Jane Gunther, Ted Yednock, Alain Stricker-Krongrad, Elizabeth Messersmith
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14314 (2010)
Restenosis remains the main complication of balloon angioplasty and/or stent implantation. Preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where restenosis is assessed after endothelial abrasion o
Externí odkaz:
https://doaj.org/article/9585ed026af64efea91ac6bcc44868f6
Publikováno v:
BMC Clinical Pathology, Vol 18, Iss 1, Pp 1-6 (2018)
BMC Clinical Pathology
BMC Clinical Pathology
Background Measuring expression profiles of inflammatory biomarkers is important in monitoring the polarization of immune responses; therefore, results should be independent of quantitation methods if they are to be accepted as validated clinical pat
Autor:
David T. White, Naijia Huang, Jeffrey S. Tan, Kenneth J. Ruterbories, Jason Liu, Derek Brocksmith, Lee J. Burns, Alain Stricker-Krongrad, Nathan Yumibe, Nita J. Patel, Guy Bouchard
Publikováno v:
International Journal of Pharmacokinetics. 2:81-91
Aim: Oral and intravenous pharmacokinetic (PK) studies were conducted in four different minipig strains: Sinclair, Yucatan, Hanford and Göttingen after administration of metformin or R,S-verapamil (R,S-VER). Results: The results indicated that the P
Autor:
Chris Hanks, Shayne C. Gad, Jason Liu, Amber Fuller, Derek Brocksmith, Miao Zhong, Guy Bouchard, Catherine Shoemake, David T. White, Alain Stricker-Krongrad
Publikováno v:
International Journal of Toxicology. 36:113-123
A functional observational battery (FOB) is recommended as the first-tier neurotoxicity screening in the preclinical safety pharmacology testing guidelines. Minipigs have increasingly been used in regulatory toxicology studies; however, no current FO
Publikováno v:
Toxicologic Pathology. 44:612-623
The use of the miniature swine as a nonrodent species in research has continued to expand for over a decade, and they are becoming routinely used both in experimental pharmacology and as a therapeutic model for human diseases. Miniature swine models
Autor:
Shayne C. Gad, Marcia E. Pereira, Guy Bouchard, Catherine Shoemake, Alain Stricker-Krongrad, Derek Brocksmith
Publikováno v:
Toxicologic Pathology. 44:421-427
The use of miniature swine as a nonrodent species in safety assessment has continued to expand for over a decade, and they are becoming routinely used in toxicology and in pharmacology as well as a model for human diseases. Miniature swine models are
Publikováno v:
Toxicology of the Gastrointestinal Tract ISBN: 9780429433252
The minipig has become a popular animal model in biomedical research. Minipigs offer advantages over domestic pigs due to their size and ease of handling, and offer a viable alternative to canine and non-human primates as a large animal model in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8b5fc368585f283f0c863d96e9979f2
https://doi.org/10.1201/9780429433252-7
https://doi.org/10.1201/9780429433252-7
Publikováno v:
Diabetes. 67
Abundant evidence shows that patients with type 1 diabetes are at high risk for several cardiovascular disorders. Our objective was to assess cardiac electro-pathophysiology changes linked to chronic insulin-dependent diabetes in the Yucatan miniatur
Publikováno v:
The Clinical Chemistry of Laboratory Animals ISBN: 9781315155807
The Clinical Chemistry of Laboratory Animals
The Clinical Chemistry of Laboratory Animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c2e0382a9e3ae8ae9fc35453729645
https://doi.org/10.1201/9781315155807-5
https://doi.org/10.1201/9781315155807-5
Autor:
Alain Stricker-Krongrad, Catherine Shoemake, Derek Brocksmith, Jason Liu, Robert Hamlin, Guy Bouchard
Publikováno v:
Toxicology Research and Application, Vol 1 (2017)
The minipig has been increasingly recognized as a valid alternative to canines and nonhuman primates in regulatory toxicity. This article presents the results of cardiovascular assessments in the Yucatan, Hanford, Sinclair, and Göttingen minipigs co