Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alain R. Bonny"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Stochastic fluctuations at the transcriptional level contribute to heterogeneity in isogenic cell populations. Here, the authors engineer TuNR which modulates the variability in gene expression of endogenous human genes independent of their mean expr
Externí odkaz:
https://doaj.org/article/40c72744eec947a8be9ff201dea8efdf
Autor:
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S Azimi, Caleigh M Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M Boileau, Saumya R Bollam, Alain R Bonny, David Booth, Michael Jerico B Borja, David Brown, Bryan Buie, Cassandra E Burnett, Lauren E Byrnes, Katelyn A Cabral, Joana P Cabrera, Saharai Caldera, Gabriela Canales, Gloria R Castañeda, Agnes Protacio Chan, Christopher R Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D Chow, Y Rose Citron, Allison Cohen, Lillian B Cohn, Charles Chiu, Mitchel A Cole, Daniel N Conrad, Angela Constantino, Andrew Cote, Tre'Jon Crayton-Hall, Spyros Darmanis, Angela M Detweiler, Rebekah L Dial, Shen Dong, Elias M Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M Frumm, Becky Xu Hua Fu, Valentina E Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M Grace Gordon, James C R Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J Howard, Jeffrey A Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R Jackson, Ziad M Jowhar, Danielle Kain, James Y S Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F Kung, Charles Langelier, Matthew T Laurie, Lena Lee, Kun Leng, Kristoffer E Leon, Manuel D Leonetti, Sophia R Levan, Sam Li, Aileen W Li, Jamin Liu, Heidi S Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M Marquez, Bryan P Marsh, Calla Martyn, Elizabeth E McCarthy, Aaron McGeever, Alexander F Merriman, Lauren K Meyer, Steve Miller, Megan K Moore, Cody T Mowery, Tanzila Mukhtar, Lusajo L Mwakibete, Noelle Narez, Norma F Neff, Lindsay A Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R Puccinelli, Andreas S Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F Rosenberg, Estella Sanchez-Guerrero, Sydney M Sattler, Laura Savy, Stephanie K See, Kristin K Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M Tato, Jack C Taylor, Iliana Tenvooren, Erin M Thompson, Edward C Thornborrow, Eric Tse, Tony Tung, Marc L Turner, Victoria S Turner, Rigney E Turnham, Mary J Turocy, Trisha V Vaidyanathan, Ilia D Vainchtein, Manu Vanaerschot, Sara E Vazquez, Anica M Wandler, Anne Wapniarski, James T Webber, Zara Y Weinberg, Alexandra Westbrook, Allison W Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L DeRisi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
Externí odkaz:
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Autor:
Katherine S Stewart, Kevin AU Gonzales, Shaopeng Yuan, Matthew T Tierney, Alain R Bonny, Yihao Yang, Nicole R Infarinato, Christopher J Cowley, John M Levorse, Hilda Amalia Pasolli, Sourav Ghosh, Carla V Rothlin, Elaine Fuchs
Publikováno v:
bioRxiv
Summary ParagraphMacrophages and dendritic cells have long been appreciated for their ability to migrate to and engulf dying cells and debris, including some of the billions of cells that are naturally eliminated from our body daily. However, a subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a46b51258f8a875f888d36c01949c4
https://europepmc.org/articles/PMC10245816/
https://europepmc.org/articles/PMC10245816/
Autor:
Lindsey C. Osimiri, Alain R. Bonny, Seesha R. Takagishi, Stefanie Luecke, Nina Riehs, Alexander Hoffmann, Hana El-Samad
Many transcription factors (TFs) translocate to the nucleus with varied dynamic patterns in response to different inputs. A notable example of such behavior is RelA, a subunit of NF-κB, which translocates to the nucleus with either pulsed or sustain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c47ddb56dd3ee431228423db6f1e428d
https://doi.org/10.1101/2022.08.03.502739
https://doi.org/10.1101/2022.08.03.502739
Autor:
David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser
Publikováno v:
eLife, Vol 5 (2016)
Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance
Externí odkaz:
https://doaj.org/article/f3e8373dbc7b4012a1c82425c9fb49fb
Publikováno v:
Cell Reports, 34 (11)
A near-constant feature of stress responses is a downregulation or arrest of the cell cycle, resulting in transient growth slowdown. To investigate the role of growth slowdown in the hyperosmotic shock response of S. cerevisiae, we perturbed the G1/S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d511d7ff2f61d8c3d864b65b6ed3abf4
https://hdl.handle.net/20.500.11850/475545
https://hdl.handle.net/20.500.11850/475545
Autor:
Becky Xu Hua Fu, Erin M. Thompson, Agnes Protacio Chan, Zara Y. Weinberg, Alain R Bonny, Samantha Hao, Nicholas Hoppe, Aparna Bhaduri, Angela Constantino, Fauna Yarza, Suping Peng, Lillian B. Cohn, Gajus Worthington, Paula Hayakawa Serpa, Diana M. Marquez, Rafael Gomez-Sjoberg, Saharai Caldera, Norma Neff, Neha Pincha, Peter Picard, Andrew Cote, Diter Oviedo, Shayan Hosseinzadeh, Robert Puccinelli, Danielle Ingebrigtsen, Serena Tamura, Sergei Pourmal, Jeffrey A. Hussmann, Anica M. Wandler, M. Grace Gordon, Irene Acosta, Shweta Gupta, Jeremy Bancroft Brown, Joseph L. DeRisi, Shannon Axelrod, Andreas S. Puschnik, Lindsey M. Pieper, Joseph M. Replogle, Valentina E. Garcia, James Reese, Patrick Ayscue, Arthur Charles-Orszag, Iliana Tenvooren, Eric Tse, Alison Fanton, Elze Rackaityte, Charles Y. Chiu, Aileen W. Li, Edward Thornborrow, Amy Lyden, Katelyn A. Cabral, Sukrit Silas, Kun Leng, Erika Anderson, Lusajo L. Mwakibete, Shaun Arevalo, Gabriela Canales, Calla Martyn, Gorica Margulis, Andrew F. Kung, Sophia R. Levan, Tanzila Mukhtar, Carly K. Cheung, Jonathan Sheu, Sam Li, Charles Langelier, Gloria Castaneda, Tina Zheng, Maureen Sheehy, Rebecca Egger, Amy Kistler, Alexander F. Merriman, Sara Sunshine, Cody T. Mowery, Madhura Raghavan, Allison Cohen, Terrina Yamamoto, Mitchel A. Cole, Saumya R. Bollam, Megan Moore, Preethi Raghavan, Jessie Kulsuptrakul, Stacey M. Frumm, Manu Vanaerschot, Fang Xie, Daniel Asarnow, Miriam Goldman, Pierce Hadley, Sara E. Vazquez, Michelle Tan, Kristin K. Sellers, Lindsay A. Osso, Lauren K. Meyer, Daniel N. Conrad, Sabrina A Mann, Vida Ahyong, Kristoffer E. Leon, Un Seng Chio, Camillia S. Azimi, Bryan Marsh, Anne E. Wapniarski, Stefanie Bachl, Kit Ying E. Ho, Rigney E. Turnham, Aaron McGeever, Cassandra E. Burnett, Rebekah Dial, Caleigh M. Azumaya, Helen Reyes, Victoria S. Turner, Jiongyi Tan, Emily D. Crawford, Allison W. Wong, Spyros Darmanis, Shen Dong, Lena Lee, Y. Rose Citron, Christopher R. Chang, Astrid Behnert, Ziad M. Jowhar, Nadia Herrera, Doug Stryke, Lauren Byrnes, Albert Xu, James C. R. Grove, Cristina M. Tato, George C. Hartoularos, Tony Tung, Iris Bachmutsky, Ryan M. Boileau, Peter Suslow, Jessica Streithorst, Alexis Haddjeri-Hopkins, John R. Haliburton, Conor J Howard, Angela Oliveira Pisco, Eric D. Chow, Elizabeth E. McCarthy, Joshua Batson, Oriana Kreutzfeld, Elizabeth Hwang, Hanna Retallack, Danielle Kain, Alice Tang, Jack C. Taylor, Emily C. Wong, Donald Rose, Julia R. Jackson, Alexandra Westbrook, Matthew T. Laurie, Jennifer Mann, Renaldo Sutanto, Mary J. Turocy, Trisha V. Vaidyanathan, Melissa Hilberg, Stephanie K. See, David S. Booth, Christina Gladkova, Jack Strickland, Julie M. Garcia, Marc L. Turner, David Dynerman, Manuel D. Leonetti, Laura Savy, Noelle Narez, Jamin Liu, Ilia D. Vainchtein, Ying Yang, Kiet T. Phong, Tre’Jon Crayton-Hall, David Brown, Marci F. Rosenberg, Bryan Buie, Maira Phelps, Sydney M. Sattler, Elias Duarte, Yefim Zaltsman, Angela M. Detweiler, Estella Sanchez-Guerrero, Joana P. Cabrera, Michael Jerico B. Borja, James Y. S. Kim, Heidi S. Lubin, Angela Pogson, Steve Miller, James T. Webber
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
PLoS Pathogens
PLoS Pathogens
Author(s): Crawford, Emily D; Acosta, Irene; Ahyong, Vida; Anderson, Erika C; Arevalo, Shaun; Asarnow, Daniel; Axelrod, Shannon; Ayscue, Patrick; Azimi, Camillia S; Azumaya, Caleigh M; Bachl, Stefanie; Bachmutsky, Iris; Bhaduri, Aparna; Brown, Jeremy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f769d674844a50804f8ecde46fb4c3
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140
Stochastic fluctuations at the transcriptional level contribute to isogenic cell-to-cell heterogeneity in mammalian cell populations. However, we still have no clear understanding of the repercussions of this heterogeneity, given the lack of tools to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4db15fdbb62d7d42c9834f4170488cc
https://doi.org/10.1101/2020.05.23.112979
https://doi.org/10.1101/2020.05.23.112979
The ability of a cell to mount a robust response to an environmental perturbation is paramount to its survival. While cells deploy a spectrum of specialized counter-measures to deal with stress, a near constant feature of these responses is a down re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce71d8d27eee1b8a524679e3a63ffa82
https://doi.org/10.1101/2020.04.08.033035
https://doi.org/10.1101/2020.04.08.033035
Publikováno v:
Bio Protoc
The ability to rapidly assemble and prototype cellular circuits is vital for biological research and its applications in biotechnology and medicine. The Mammalian ToolKit (MTK) is a Golden Gate-based cloning toolkit for fast, reproducible and versati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d79b178c9a5187ab6b0de43b00d02c
https://doi.org/10.21769/bioprotoc.3547
https://doi.org/10.21769/bioprotoc.3547