The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation

Autor: Bruno Mugat, Simon Nicot, Carolina Varela-Chavez, Christophe Jourdan, Kaoru Sato, Eugenia Basyuk, François Juge, Mikiko C. Siomi, Alain Pélisson, Séverine Chambeyron

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

In S. pombe, small non-coding RNA mediates heterochromatin formation by recruiting the nucleosome remodeling and histone deacetylase complex. Here, the authors show that fly nucleosome remodeler Mi-2 and histone deacetylase Rpd3 are involved in piRNA

Externí odkaz: https://doaj.org/article/0dee362d68ea48919fcea68a5a855269

MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells.

Autor: Bruno Mugat, Abdou Akkouche, Vincent Serrano, Claudia Armenise, Blaise Li, Christine Brun, Tudor A Fulga, David Van Vactor, Alain Pélisson, Séverine Chambeyron

Publikováno v: PLoS Genetics, Vol 11, Iss 5, p e1005194 (2015)

RNA interference-related silencing mechanisms concern very diverse and distinct biological processes, from gene regulation (via the microRNA pathway) to defense against molecular parasites (through the small interfering RNA and the Piwi-interacting R

Externí odkaz: https://doaj.org/article/fdfe3febb61a42029693c27cbaa78fbf

A transposon story : from TE content to TE dynamic invasion of Drosophila genomes using the single-molecule sequencing technology from Oxford Nanopore

Autor: Séverine Chambeyron, Nelly Burlet, Judit Salces-Ortiz, Bruno Mugat, Philippe Veber, François Sabot, Nguyet Thi-Minh Dang, Alain Pélisson, Marie Fablet, Cristina Vieira, Yuki Ogyama, Vincent Mérel, Matthieu Boulesteix, Mourdas Mohamed, Dany Severac

Publikováno v: Cells
Cells, MDPI, In press, ⟨10.3390/cells9081776⟩
Cells, 2020, 9 (8), pp.1776. ⟨10.3390/cells9081776⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 9
Issue 8
Cells, MDPI, 2020, 9 (8), pp.1776. ⟨10.3390/cells9081776⟩
Cells, Vol 9, Iss 1776, p 1776 (2020)

Transposable elements (TEs) are the main components of genomes. However, due to their repetitive nature, they are very difficult to study using data obtained with short-read sequencing technologies. Here, we describe an efficient pipeline to accurate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0e32791a8fbe4b11174f1d2306c731
http://www.documentation.ird.fr/hor/fdi:010079692

A user-friendly chromatographic method to purify small regulatory RNAs

Autor: Bruno Mugat, Alain Pélisson, Claudia Armenise, Thomas Grentzinger, Séverine Chambeyron, Christine Brun

Publikováno v: Methods. 67:91-101

The discovery of the small regulatory RNAs has changed our vision of cellular regulations. Indeed, when loaded on Argonaute proteins they form ribonucleoprotein complexes (RNPs) that target complementary sequences to achieve widespread silencing mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a347eb3d45d1e7e45d924c6f1d1e76
https://doi.org/10.1016/j.ymeth.2013.05.011

Evidence for a piwi-Dependent RNA Silencing of the gypsy Endogenous Retrovirus by the Drosophila melanogaster flamenco Gene

Autor: Alain Bucheton, Alain Pélisson, Geneviève Payen-Groschêne, Emeline Sarot

Publikováno v: Genetics. 166:1313-1321

In Drosophila melanogaster, the endogenous retrovirus gypsy is repressed by the functional alleles (restrictive) of an as-yet-uncloned heterochromatic gene called flamenco. Using gypsy-lacZ transcriptional fusions, we show here that this repression t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07894853193a5c85b7b7115823c6f150
https://doi.org/10.1534/genetics.166.3.1313