Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alain Niveleau"'
Autor:
Manel Esteller, Amparo Cano, Alan Balmain, Jian-Hua Mao, Alain Niveleau, Héctor Peinado, Onder Bozdogan, Emel Erkek, Santiago Ropero, Maria F. Paz, Esteban Ballestar, Jesús Espada, Michel Herranz, Mario F. Fraga
Supplementary Tables from A Mouse Skin Multistage Carcinogenesis Model Reflects the Aberrant DNA Methylation Patterns of Human Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8da6d98afdee68fa89b25c169af39e
https://doi.org/10.1158/0008-5472.22363739
https://doi.org/10.1158/0008-5472.22363739
Autor:
Manel Esteller, Amparo Cano, Alan Balmain, Jian-Hua Mao, Alain Niveleau, Héctor Peinado, Onder Bozdogan, Emel Erkek, Santiago Ropero, Maria F. Paz, Esteban Ballestar, Jesús Espada, Michel Herranz, Mario F. Fraga
Whereas accepted models of tumorigenesis exist for genetic lesions, the timing of epigenetic alterations in cancer is not clearly understood. We have analyzed the profile of aberrations in DNA methylation occurring in cells lines and primary tumors o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a056cfcfd23f3cdd8df0c1283c466dd
https://doi.org/10.1158/0008-5472.c.6493865
https://doi.org/10.1158/0008-5472.c.6493865
Autor:
William E. Grizzle, Alain Niveleau, Edmond K. Kabagambe, Maurizio Macaluso, Nirag Jhala, Darshana Jhala, Ilene Brill, Maria Azrad, Chandrika J. Piyathilake
Publikováno v:
Cancer Biomarkers. 2:259-266
The purpose of this study was to evaluate whether mandatory fortification of grain products with folic acid in the USA is associated with changes in global DNA methylation in cells involved in cervical carcinogenesis. Archived specimens of cervical i
Publikováno v:
Gynécologie Obstétrique & Fertilité. 34:836-839
In the last few years, many tests were developed to study the fertilizing properties of the spermatozoa. However none of them was useful to obtain a prognostic factor. Indeed, the integrity of the spermatic DNA is also necessary to a successful ferti
Autor:
Alain Niveleau, Jean Michel Prades, Bruno Estour, Sandrine Lassandre, Bogdan Galusca, Michel Peoc'h, Jean Marc Dumollard
Publikováno v:
Virchows Archiv. 447:18-23
The implications of global DNA hypomethylation were recently reported in several models of tumorigenesis. Little is known about this epigenetic event in thyroid neoplasia. The study aimed to evaluate the status of global DNA methylation in several ty
Autor:
Douglas C. Heimburger, William E. Grizzle, Jennifer Jones, Walter C. Bell, Olga L. Henao, Chandrika J. Piyathilake, Alain Niveleau
Publikováno v:
Disease markers
Disease Markers, Vol 21, Iss 3, Pp 147-151 (2005)
Disease Markers, Vol 21, Iss 3, Pp 147-151 (2005)
Although there is growing interest in the possibility that alterations in histone methylation may play a role in carcinogenesis, it has not been explored adequately in humans. Similarly, there are no reports of associations between this and a similar
Publikováno v:
Journal of Biological Chemistry. 278:14985-14995
The DNA methylation pattern is an important component of the epigenome that regulates and maintains gene expression programs. In this paper, we test the hypothesis that vertebrate cells possess mechanisms protecting them from epigenomic stress simila
Autor:
Douglas C. Heimburger, Walter C. Bell, Alain Niveleau, Chandrika J. Piyathilake, Gary L. Johanning, Andra R. Frost, Olga L. Henao, William E. Grizzle, Maurizio Macaluso
Publikováno v:
Cancer Causes and Control. 14:37-42
Objective: The current study investigated the race- and age-dependent alterations in global DNA methylation on the development and progression of squamous cell carcinomas (SCCs) of the lung. Methods: Methylation status was evaluated in SCC and in the
Publikováno v:
Developmental Biology. 243(1):155-165
The levels of genomic DNA methylation in vertebrate species display a wide range of developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the amphibian, Xenopus laevis, is not subjected to active demethylation of 5-me
Publikováno v:
Chromosome Research. 8:513-525
DNA methylation of sex chromosomes was analysed using anti-5-methylcytosine antibodies on metaphase chromosomes of somatic cells from three species: human, lemur and mouse. Germ cells were also studied in male mouse. In female cells (human and mouse)