Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alain Mazé"'
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1426-1433 (2014)
The ability of Salmonella to cause disease depends on metabolic activities and virulence factors. Here, we show that a key metabolic protein, EIIAGlc, is absolutely essential for acute infection, but not for Salmonella survival, in a mouse typhoid fe
Externí odkaz:
https://doaj.org/article/299635a2d2b441568957632bfd8f46df
Autor:
Benjamin Steeb, Beatrice Claudi, Neil A Burton, Petra Tienz, Alexander Schmidt, Hesso Farhan, Alain Mazé, Dirk Bumann
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003301 (2013)
Pathogen access to host nutrients in infected tissues is fundamental for pathogen growth and virulence, disease progression, and infection control. However, our understanding of this crucial process is still rather limited because of experimental and
Externí odkaz:
https://doaj.org/article/9f2977f5f5254229b1977c5bfa83ab54
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42007 (2012)
Chronic infections caused by persistent pathogens represent an important health problem. Here, we establish a simple practical mouse Salmonella infection model for identifying bacterial maintenance functions that are essential for persistency. In thi
Externí odkaz:
https://doaj.org/article/b8f1cbbb7b5e4b82b695a0c1f2e90cbb
Autor:
Somedutta Barat, Yvonne Willer, Konstantin Rizos, Beatrice Claudi, Alain Mazé, Anne K Schemmer, Dennis Kirchhoff, Alexander Schmidt, Neil Burton, Dirk Bumann
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002966 (2012)
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum. Novel vaccines with broad serovar coverage are needed, but suitable protective antigen
Externí odkaz:
https://doaj.org/article/896b33ce87dc41e19002c8e71a86899a
Autor:
Marie Dozot, Sandrine Poncet, Cécile Nicolas, Richard Copin, Houda Bouraoui, Alain Mazé, Josef Deutscher, Xavier De Bolle, Jean-Jacques Letesson
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12679 (2010)
In many bacteria, the phosphotransferase system (PTS) is a key player in the regulation of the assimilation of alternative carbon sources notably through catabolic repression. The intracellular pathogens Brucella spp. possess four PTS proteins (EINtr
Externí odkaz:
https://doaj.org/article/6bc0d01cef304af3ac9018d6e5ac8036
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 91:118-122
The amikacin plus gentamicin-containing SuperAminoglycoside medium was developed for screening multiple-aminoglycoside resistance in Gram-negative bacteria (Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii). It was evaluated us
Autor:
Yaakov Benenson, Alain Mazé
Publikováno v:
Nature Chemical Biology, 16 (2)
Augmenting live cells with new signal transduction capabilities is a key objective in genetic engineering and synthetic biology. We showed earlier that two-component signaling pathways could function in mammalian cells, albeit while losing their liga
Autor:
Philippe Joyet, Sandrine Poncet, Muhamed-Kheir Taha, Ala-Eddine Deghmane, Meriem Derkaoui, Jamila Nait Abdallah, Alain Mazé, Céline Henry, Ana Antunes, Josef Deutscher
Publikováno v:
Molecular Microbiology. 100:788-807
The bacterial phosphotransferase system (PTS) transports and phosphorylates sugars, but also carries out numerous regulatory functions. The β-proteobacterium Neisseria meningitidis possesses an incomplete PTS unable to transport carbon sources becau
Autor:
Meriem Derkaoui, Alain Mazé, Jamila Nait Abdallah, Ala-Eddine Deghmane, Que Mai Ma Pham, Philippe Joyet, Sandrine Poncet, Muhamed-Kheir Taha, Abdelhamid Mokhtari, Josef Deutscher, Ana Antunes
Publikováno v:
Microbial Physiology. 26:320-332
We identified the genes encoding the proteins for the transport of glucose and maltose in Neisseria meningitidis strain 2C4-3. A mutant deleted for NMV_1892(glcP) no longer grew on glucose and deletion of NMV_0424(malY) prevented the utilization of m
Autor:
Jean-Marie Laplace, Alain Mazé, Yanick Auffray, Axel Hartke, Sophie Beaufils, Nicolas Sauvageot, Josef Deutscher
Publikováno v:
Microbial Physiology. 13:65-75
When carrying out a proteome analysis with a ptsH3 mutant of Lactobacillus casei, we found that the cold shock protein CspA was significantly overproduced compared to the wild-type strain. We also noticed that CspA and CspB of L. casei and CSPs from