Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Alain Le Moine"'
Autor:
Tess Van Meerhaeghe, Alain Le Moine
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Externí odkaz:
https://doaj.org/article/0bacd2e7c0444230a10b05fa7599787f
Autor:
Benedetta Chiodini, Pauline Guillaume-Gentil, Charlotte Vanhomwegen, Elise Hennaut, Ksenija Lolin, Nathalie Tram, Alain Le Moine, Khalid Ismaili
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1093 (2024)
BK polyomavirus (BKPyV) is still a real threat in the management of kidney transplantation. Immunosuppressive treatment disrupts the equilibrium between virus replication and immune response, and uncontrolled BKPyV replication leads to nephropathy (B
Externí odkaz:
https://doaj.org/article/93c41efdbe0a4f4ebde712e6c602c8eb
Autor:
Giuseppe Gambino, Concetta Catalano, Martina Marangoni, Caroline Geers, Alain Le Moine, Nathalie Boon, Guillaume Smits, Lidia Ghisdal
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Ciliopathies are rare diseases causing renal and extrarenal manifestations. Here, we report the case of a ciliopathy induced by a homozygous pathogenic variant in the TTC21B gene.Case Description: A 47-year-old patient started hemodialysi
Externí odkaz:
https://doaj.org/article/5432b41b12224d4ea6a3b0bc7c8ad062
Autor:
Chloé Spilleboudt, Virginie De Wilde, Philippe Lewalle, Ludovic Cabanne, Mathieu Leclerc, Florence Beckerich, Dominique Bories, Silvia Cardoso, Miguel P. Soares, Benoît Vokaer, Jean-Michel Hougardy, Véronique Flamand, Judith Racapé, Marc Abramowicz, Sébastien Maury, Alain Le Moine
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Graft-versus-host disease (GVHD) remains a major clinical drawback of allogeneic hematopoietic stem cell transplantation (HSCT). Here, we investigated how the stress responsive heme catabolizing enzyme heme oxygenase-1 (HO-1, encoded by HMOX1) regula
Externí odkaz:
https://doaj.org/article/bf844a85d1ce4939bdde8c6a1163b84d
Specific expression of heme oxygenase-1 by myeloid cells modulates renal ischemia-reperfusion injury
Autor:
Maxime Rossi, Antoine Thierry, Sandrine Delbauve, Nicolas Preyat, Miguel P. Soares, Thierry Roumeguère, Oberdan Leo, Véronique Flamand, Alain Le Moine, Jean-Michel Hougardy
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Renal ischemia-reperfusion injury (IRI) is a major risk factor for delayed graft function in renal transplantation. Compelling evidence exists that the stress-responsive enzyme, heme oxygenase-1 (HO-1) mediates protection against IRI. Howeve
Externí odkaz:
https://doaj.org/article/527ac6c697954f86bb929297f1a96352
Autor:
Martin Chaumont, Judith Racapé, Nilufer Broeders, Fadoua El Mountahi, Annick Massart, Thomas Baudoux, Jean-Michel Hougardy, Dimitri Mikhalsky, Anwar Hamade, Alain Le Moine, Daniel Abramowicz, Pierre Vereerstraeten
Publikováno v:
Journal of Transplantation, Vol 2015 (2015)
Background. Although numerous risk factors for delayed graft function (DGF) have been identified, the role of ischemia-reperfusion injury and acute rejection episodes (ARE) occurring during the DGF period is ill-defined and DGF impact on patient and
Externí odkaz:
https://doaj.org/article/3317ffe0c47142ab8a0d387e13cf38b7
Autor:
Claude Sadis, Sophie Detienne, Benoît Vokaer, Louis-Marie Charbonnier, Philippe Lemaître, Chloé Spilleboudt, Sandrine Delbauve, Carole Kubjak, Véronique Flamand, Kenneth A Field, Michel Goldman, Fleur S Benghiat, Alain Le Moine
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79984 (2013)
Activation of innate immunity through Toll-like receptors (TLR) can abrogate transplantation tolerance by revealing hidden T cell alloreactivity. Separately, the cholinergic anti-inflammatory pathway has the capacity to dampen macrophage activation a
Externí odkaz:
https://doaj.org/article/78cf1e163231466e87118c88cf7b9754
IL-17A mediates early post-transplant lesions after heterotopic trachea allotransplantation in Mice.
Autor:
Philippe H Lemaître, Benoît Vokaer, Louis-Marie Charbonnier, Yoichiro Iwakura, Marc Estenne, Michel Goldman, Oberdan Leo, Myriam Remmelink, Alain Le Moine
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70236 (2013)
Primary graft dysfunction (PGD) and bronchiolitis obliterans (BO) are the leading causes of morbidity and mortality after lung transplantation. Reports from clinical and rodent models suggest the implication of IL-17A in either PGD or BO. We took adv
Externí odkaz:
https://doaj.org/article/f6ccf342ae96442fbb80bbc2b9714cdd
Autor:
Benoît Vokaer, Louis-Marie Charbonnier, Philippe H Lemaître, Chloé Spilleboudt, Alain Le Moine
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76040 (2013)
Several evidences suggest that regulatory T cells (Treg) promote Th17 differentiation. Based on this hypothesis, we tested the effect of IL-17A neutralization in a model of skin transplantation in which long-term graft survival depends on a strong in
Externí odkaz:
https://doaj.org/article/5d630bb0ea09415292bbe7617022b78c
Autor:
Claude Sadis, Gwen Teske, Geurt Stokman, Carole Kubjak, Nike Claessen, Fabrice Moore, Patrizia Loi, Bilo Diallo, Luc Barvais, Michel Goldman, Sandrine Florquin, Alain Le Moine
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e469 (2007)
Kidney ischemia/reperfusion injury (I/R) is characterized by renal dysfunction and tubular damages resulting from an early activation of innate immunity. Recently, nicotine administration has been shown to be a powerful inhibitor of a variety of inna
Externí odkaz:
https://doaj.org/article/acb94e411d8b4b01ad30b4704c58afa6