Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Alain Klaebe"'
Autor:
Fabienne Briand-Mesange, François Tercé, Michéle Wilson, Geneviéve Gueguen, Virginie Granci, Hugues Chap, Jean-Pierre Salles, Marie-Françoise Simon, Pierre Rogalle, Frédérique Gaits, Alain Klaebe
Publikováno v:
Biochemical Journal. 368:447-459
A previous study demonstrated that cross-desensitization experiments performed with the lysophosphatidic acid (LPA) analogues (R)- and (S)-N-palmitoyl-norleucinol 1-phosphate (PNPAs) inhibited LPA-induced platelet aggregation without any stereospecif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559cca9bf1adff48495253c60f11c894
https://doi.org/10.1042/bj20020273
https://doi.org/10.1042/bj20020273
Autor:
Estelle Barbier, Jean Marie François, Hassan Hajjaj, Alain Klaebe, Gérard Goma, Philippe Blanc
Publikováno v:
Applied and Environmental Microbiology. 66:1120-1125
In filamentous fungi, many secondary metabolites with complex chemical structures are synthesized from the polyketide pathway (26, 29). These metabolites display a wide range of biological activities, including antibiotic, antifungal, immunosuppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb54ec4ce01604e8b58fc3ea9bc8f772
https://doi.org/10.1128/aem.66.3.1120-1125.2000
https://doi.org/10.1128/aem.66.3.1120-1125.2000
Autor:
Frédéric Pont, Geneviève Gueguen, Alain Klaebe, Jean-Michel Grévy, J. Bellan, Bernadette Gaigé, Marie-Françoise Simon, Hugues Chap, Pierre Rogalle, Michéle Wilson
Publikováno v:
Biochemistry. 38:8440-8450
Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate or LPA) is a phospholipid mediator displaying numerous and widespread biological activities and thought to act via G-protein-coupled receptors. Here we have studied the effects on human platelets o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ef5d012270ba6327c90961987cfda8
https://doi.org/10.1021/bi9816756
https://doi.org/10.1021/bi9816756
Autor:
Ségolène Colrat, Jean-Paul Roustan, Alain Klaebe, Corine Deswarte, Jean Fallot, Mondher Bouzayen, Alain Latché
Publikováno v:
Planta. 207:544-550
Eutypine, 4-hydroxy-3-(3-methyl-3-butene-1-ynyl) benzaldehyde, is a toxin produced by Eutypa lata (Pers.: Fr.) Tul., the causal agent of dying arm disease of Vitis vinifera L. (grapevine). Previously, we have shown that eutypine is involved in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7b44f29ed4e46b63bf9444b711186d8
https://doi.org/10.1007/s004250050516
https://doi.org/10.1007/s004250050516
Autor:
Patrick Masson, Jure Stojan, Sandino Estrada-Mondaca, Alain Klaebe, Véronique Marcel, Didier Fournier
Publikováno v:
FEBS Letters. 440:85-88
Insect acetylcholinesterase, an enzyme whose catalytic site is located at the bottom of a gorge, can metabolise its substrate in a wide range of concentrations (from 1 μM to 200 mM) since it is activated at low substrate concentrations. It also pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4148d3b7a382fb09b99742ac13106fc9
https://doi.org/10.1016/s0014-5793(98)01434-3
https://doi.org/10.1016/s0014-5793(98)01434-3
Publikováno v:
Tetrahedron. 53:17241-17246
The NMR study of the reaction of methylparathion with thiol (glutathione) and a tertiary amine shows unambiguously a sequential transfer of the methyl group firstly to the amine and secondly to the thiol. The reaction stops after a single demethylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9150d608e94cff146af6b9e0e5299cb
https://doi.org/10.1016/s0040-4020(97)10176-4
https://doi.org/10.1016/s0040-4020(97)10176-4
Publikováno v:
Applied and Environmental Microbiology. 63:2671-2678
The filamentous fungus Monascus ruber produces water-soluble red pigments in a submerged culture when grown in a chemically defined medium containing glucose as a carbon source and monosodium glutamate as a nitrogen source. Two new molecules with pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554e5487b47a82932f755f4c0df294d7
https://doi.org/10.1128/aem.63.7.2671-2678.1997
https://doi.org/10.1128/aem.63.7.2671-2678.1997
Publikováno v:
Cell Biology and Toxicology. 13:141-153
The trypanocidal activity of naturally occurring 6-(3,4-dihydroxystyryl)-4-hydroxy-2-pyrone (hispidin) prompted us to examine its cytotoxic activity toward normal and cancerous cells in culture. Hispidin synthesized in our laboratory to a high degree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2c5ca346df54b850fdfab2caf5a19f
https://doi.org/10.1023/a:1007321227010
https://doi.org/10.1023/a:1007321227010
Autor:
Colette Denier, Jacques Périé, H. Vergnes, Alain E Fournie, A. Brisson-Lougarre, J. Grozdea, Alain Klaebe
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 33:215-218
Alkaline phosphatase concentrations are known to increase in blood neutrophils of normal pregnant women. The main kinetic parameters of this enzyme were analysed and compared in a group of 30 women with normal pregnancies and a group of 11 women whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460593860ddb256a3d2705e5f6e033dd
https://doi.org/10.1177/000456329603300307
https://doi.org/10.1177/000456329603300307
Publikováno v:
Journal of Plant Physiology. 149:336-342
Summary The mechanism of the toxic action of eutypine, 4-hydroxy-3-(3-methyl-3-butene-l-ynyl) benzaldehyde, a toxin produced by the fungus Eutypa lata , the agent of dying arm disease of the grapevine, was investigated with cell suspension cultures o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3ad05d850bac491c3ea830d2fe1fa3
https://doi.org/10.1016/s0176-1617(96)80131-3
https://doi.org/10.1016/s0176-1617(96)80131-3