Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alain J. Duclos"'
Publikováno v:
American Journal of Reproductive Immunology. 37:471-477
PROBLEM: There is considerable controversy concerning the root cause and mechanisms of early embryo loss. It has been suggested that most pregnancy losses occur due to morphogenetic anomalies of the embryo. It has also been suggested that the materna
Publikováno v:
Cellular Immunology. 169:309-312
Thymocytes develop in close apposition to the stromal cells of the thymus. The ontogeny of thymocytes is dependent on intimate interactions between these cells and the stromal cells. The molecular mechanisms involved in regulating thymocyte–stromal
Publikováno v:
Biology of Reproduction. 54:1088-1095
The causes and precise mechanisms leading to early embryo loss in mammals remain largely unknown, especially from a molecular point of view. Using the CBA/J x DBA/2 murine model of early spontaneous embryo loss (25-30% embryo loss), we have previousl
Publikováno v:
American Journal of Reproductive Immunology. 35:34-42
Problem Spontaneous early embryo resorption following implantation occurs in many species, but little is known regarding the causes or the prevention of early pregnancy failure. Embryo and fetal loss have widely been assumed to be due to maternal all
Publikováno v:
The Journal of Experimental Medicine
In early embryo loss, the fetus may be considered to be an allograft and, therefore, may be rejected by maternal immunocytes. However, the cytotoxic mechanisms involved are still poorly understood. We have previously shown the involvement of natural
Publikováno v:
American Journal of Reproductive Immunology. 33:354-366
PROBLEM: Even though our knowledge of the phenomenon at play at the fetoplacental interface has greatly advanced during the past years, a complete understanding of the reasons why the developing embryo is not rejected by maternal immune effector cell
Publikováno v:
Ocular immunology and inflammation. 1(4)
The anterior chamber of the eye is known to be a site of immune privilege. Particularly, the aqueous humor (AqH) appears to possess unique immunoregulatory properties. The authors have previously shown that human AqH (HAqH) may increase or decrease t
Publikováno v:
Cellular Immunology. 159:184-193
The relationship between the early cellular response to embryo implantation and subsequent embryo survival was explored. Immunohistochemistry using the anti-CD11b antibody (Mac-1) was used to localize and quantify maternal inflammatory cells present
Autor:
Malcolm G. Baines, H.J. Olney, K.A. Billingsley, Alain J. Duclos, A.R. de Fougerolles, D. K. Pomerantz, R.L. Gendron
Publikováno v:
Journal of Reproductive Immunology
The mating of CBA/j female mice (H2k) by DBA/2j male mice (H2d) typically results in an elevated incidence of spontaneous embryo loss thus providing an ideal genetically controlled laboratory model for the study of the factors causing early embryo lo
Publikováno v:
Ocular Immunology and Inflammation. 2:37-43
The use of biological assays in research often creates complex Problems of data analysis. Due to the nature of bioassays which respond to the intricate interplay between multiple factors that may either increase or decrease the readout, simple arithm