Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Alain Gumy"'
1
Anti-N-Methyl-d-Aspartate (NMDA) Receptor Encephalitis Mimicking a Primary Psychiatric Disorder in an Adolescent
Autor: Eliane Roulet-Perez, Sébastien Lebon, Irina Popea, Claire Mayor-Dubois, Alain Gumy, Nalini Selvadoray, Claudia Poloni
Publikováno v: Journal of Child Neurology. 27:1607-1610
Anti- N-methyl-d-aspartate (anti-NMDA) receptor encephalitis likely has a wider clinical spectrum than previously recognized. This article reports a previously healthy 16-year-old girl who was diagnosed with anti-NMDA receptor encephalitis 3 months a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9676fd95a83787eec036db425cb0aa
https://doi.org/10.1177/0883073812438099
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2
IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice
Autor: Klaus Heeg, Hayo Himmelrich, Stephan Zimmermann, Hermann Wagner, Martin Röcken, Alain Gumy, Tilo Biedermann, Oliver Egeter, Irene Seegmüller, Pascal Launois, Jacques A. Louis, Heike Voigt, Arne Klaus Sakrauski, Alan D. Levine
Publikováno v: Nature Immunology. 2:1054-1060
Immunity to infection with intracellular pathogens is regulated by interleukin 12 (IL-12), which mediates protective T helper type 1 (TH1) responses, or IL-4, which induces TH2 cells and susceptibility. Paradoxically, we show here that when present d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cf01ce9ee239321670e3afdea96ba3
https://doi.org/10.1038/ni725
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3
Natural killer cells activated by MHC class I(low) targets prime dendritic cells to induce protective CD8 T cell responses
Autor: Anja Bubeck, Heidi Braumüller, Ulrich H. Koszinowski, Alain Gumy, Uwe Reusch, Gert Riethmüller, Oliver Egeter, Ralph Mocikat, Jacques A. Louis, Heike Ziegler, Reinhard Mailhammer, Martin Röcken
Publikováno v: Immunity. 19(4)
Conserved molecular patterns derived from pathogenic microorganisms prime antigen-presenting dendritic cells (DC) to induce adaptive T cell responses. In contrast, virus-infected or tumor cells that express low levels of major histocompatibility comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78360db4b5a39fec2de8c4466721fa51
https://pubmed.ncbi.nlm.nih.gov/14563320
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4
The murine model of infection with Leishmania major and its importance for the deciphering of mechanisms underlying differences in Th cell differentiation in mice from different genetic backgrounds
Autor: Jacques A. Louis, Pascal Launois, Alain Gumy
Publikováno v: International journal for parasitology. 34(4)
Mice from the majority of inbred strains are resistant to infection by Leishmania major, an obligate intracellular protozoan parasite of macrophages in the mammalian host. In contrast, mice from BALB strains are unable to control infection and develo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dcbe41161f2f95e4ba73521801e84a
https://pubmed.ncbi.nlm.nih.gov/15013733
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7
The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells
Autor: Fabienne Tacchini-Cottier, H. Robson MacDonald, Jacques A. Louis, Pascal Launois, Alain Gumy, Abraham Aseffa
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 169(6)
Susceptibility and development of Th2 cells in BALB/c mice infected with Leishmania major result from early IL-4 production by Vβ4Vα8 CD4+ T cells in response to the Leishmania homolog of mammalian RACK1 Ag. A role for CD4+CD25+ regulatory T cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e85e56391efd52f51b0f6a4ac21dbaa
https://pubmed.ncbi.nlm.nih.gov/12218142
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8
Experimental cutaneous Leishmaniasis: a powerful model to study in vivo the mechanisms underlying genetic differences in Th subset differentiation
Autor: Jacques, Louis, Alain, Gumy, Heike, Voigt, Martin, Röcken, Pascal, Launois
Publikováno v: European journal of dermatology : EJD. 12(4)
The murine model of infection with Leishmania major has allowed the demonstration in vivo of the importance CD4+ T cell subsets, distinguishable by the pattern of cytokines they produce, on the outcome of infectious diseases. Genetically determined r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbed79dc55f5080280cc2746beeaca88
https://pubmed.ncbi.nlm.nih.gov/12095873
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9
Rapid IL-4 production by Leishmania homolog of mammalian RACK1-reactive CD4(+) T cells in resistant mice treated once with anti-IL-12 or -IFN-gamma antibodies at the onset of infection with Leishmania major instructs Th2 cell development, resulting in nonhealing lesions
Autor: Pascal Launois, Martin Röcken, Hayo Himmelrich, Alain Gumy, Richard M. Locksley, Jacques A. Louis
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 168(9)
Rapid production of IL-4 by Leishmania homolog of mammalian RACK1 (LACK)-reactive CD4+ T cells expressing the Vβ4-Vα8 TCR chains has been shown to drive aberrant Th2 cell development and susceptibility to Leishmania major in BALB/c mice. In contras
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e63a7550a3f1f79c6799d879ff70ed1
https://pubmed.ncbi.nlm.nih.gov/11971011
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