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Regular consumption of Fiit-ns, a polyphenol extract from fruit and vegetables frequently consumed within the Mediterranean diet, improves metabolic ageing of obese volunteers: a randomized, double-blind, parallel trial

Autor: Julien Cases, Alain Gerbi, Cindy Romain, Constantin Dallas, Maurice Cloarec

Publikováno v: International Journal of Food Sciences and Nutrition. 66:120-125

Epidemiological studies suggest that metabolic ageing process of overweight and obese populations is associated with an increased risk of developing non-communicable diseases (NCDs). Inflammation, hyper-glycaemia, dyslipidemia and oxidative stress ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81753bf0119e07965d5c4dec15232e67
https://doi.org/10.3109/09637486.2014.971229

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Clinical Study to Assess the Efficacy and Safety of a Citrus Polyphenolic Extract of Red Orange, Grapefruit, and Orange (Sinetrol-XPur) on Weight Management and Metabolic Parameters in Healthy Overweight Individuals

Autor: Alain Gerbi, Yves Elbez, Maurice Cloarec, Nicolas Zamaria, Philippe Caillard, Constantin Dallas

Publikováno v: Phytotherapy Research. 28:212-218

The present study investigated the efficacy and safety effects of Sinetrol-XPur (polyphenolic citrus dry extract) in weight management; metabolic parameters; and inflammatory, glycemic and oxidative status. In a 12-week, randomized, double-blind, pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fb03e8adf81e5832ca599ef81935739
https://doi.org/10.1002/ptr.4981

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Dietary docosahexaenoic acid-enriched glycerophospholipids exert cardioprotective effects in ouabain-treated rats via physiological and metabolic changes

Autor: Martine Armand, Jean-Michel Maixent, Gérard Pieroni, Patrick J. Cozzone, T. Coste, Alain Gerbi, Monique Bernard, Carole Lan

Publikováno v: Food and Function
Food and Function, Cambridge : Royal Society of Chemistry, 2016, 7 (2), pp.798--804. ⟨10.1039/c5fo01300c⟩
Food and Function, Cambridge : Royal Society of Chemistry, 2016, 7 (2), pp.798-804. ⟨10.1039/c5fo01300c⟩
Food and Function, 2016, 7 (2), pp.798--804. ⟨10.1039/c5fo01300c⟩

International audience; Docosahexaenoic acid (DHA) might prevent heart failure or optimise drug treatments by improving cardiac contraction. We investigated whether DHA-enriched avian glycerophospholipids (GPL-DHA) exert cardioprotection in ouabain-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeadc69aa21841cd29ac3aeb136667c
https://hal-amu.archives-ouvertes.fr/hal-01425523

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Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE)

Autor: Franck Juchaux, François-Xavier Bernard, Guillaume Tenca, Alain Gerbi, Constantin Dallas

Publikováno v: Phytomedicine. 15:783-792

The present study investigated the lipolytic (break of fat stored) effect of a citrus-based polyphenolic dietary supplement (SINETROL) at human adipocytes ( ex vivo ), body fat (clinical) and biochemical levels (inhibition of phosphodiesterase). Free

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb59913f25429d98a062e61e81ea8f62
https://doi.org/10.1016/j.phymed.2008.05.006

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At Low Doses, a γ-Linolenic Acid-Lipoic Acid Conjugate Is More Effective Than Docosahexaenoic Acid-Enriched Phospholipids in Preventing Neuropathy in Diabetic Rats

Autor: Philippe Vague, Geérard Pieroni, Alain Gerbi, Denis Raccah, Seéverine Pitel, Thierry C. Coste

Publikováno v: The Journal of Nutrition. 137:368-372

A deficiency in essential fatty acid metabolism has been reported in diabetes. Nutritional supplementations with (n-6) or (n-3) PUFA have differential efficiency on parameters of diabetic neuropathy, including nerve conduction velocity (NCV) and nerv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94451dbbf4c63ee41f2fb66fa4531557
https://doi.org/10.1093/jn/137.2.368

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A 12-week randomized double-blind parallel pilot trial of Sinetrol XPur on body weight, abdominal fat, waist circumference, and muscle metabolism in overweight men

Autor: Cindy Romain, Constantin Dallas, Jean Max Rouanet, Alain Gerbi, Julien Cases

Publikováno v: International journal of food sciences and nutrition. 66(4)

Overweight and obesity are associated to increased risk of developing non-communicable diseases that might dramatically affect life expectancy according World Health Organization. Overweight, obesity, and decline in physical activity are correlated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f0c1bfe539c9b240cc25a52e705791
https://pubmed.ncbi.nlm.nih.gov/26037199

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Les supplémentations nutritionnelles en acides gras polyinsaturés dans le traitement de la neuropathie diabétique périphérique

Autor: T C Coste, Alain Gerbi, Denis Raccah, Gérard Pieroni, Martine Armand, P. Vague

Publikováno v: Cahiers de Nutrition et de Diététique. 39:185-194

Resume L’acide linoleique et l’acide alpha linolenique sont les deux acides gras essentiels et les precurseurs des familles d’acides gras polyinsatures n-6 et n-3 respectivement. Ces acides gras polyinsatures exercent un puissant role regulateu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e33d4afaffb109818407fee141bc139d
https://doi.org/10.1016/s0007-9960(04)94452-5

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Differential Effect of w3 PUFA Supplementations on Na,K-ATPase and Mg-ATPase Activities: Possible Role of the Membrane w6/w3 Ratio

Autor: Gérard Pieroni, A. Djemli-Shipkolye, D. Raccah, Alain Gerbi, P. Vague, T. Coste

Publikováno v: Journal of Membrane Biology. 191:37-47

Several functional properties of Na,K-ATPase are strongly dependent on membrane fatty acid composition, but the underlying mechanism is still not well defined. We have studied the effects of two types of supplementations enriched in the w3 polyunsatu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50aeccb2e8cd112a51d4c5f74c8877a1
https://doi.org/10.1007/s00232-002-1039-z

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Localization of Na,K-ATPase α/β Isoforms in Rat Sciatic Nerves : Effect of Diabetes and Fish Oil Treatment

Autor: Alain Gerbi, J. Sampol, Denis Raccah, Souad Sennoune, Jean-Michel Maixent, Ph. Vague, Sandrine V. Pierre

Publikováno v: Journal of Neurochemistry. 73:719-726

The localization of the Na,K-ATPase isoenzymes in sciatic nerve remains controversial, as well as diabetes-induced changes in Na,K-ATPase isoforms. Some of these changes could be prevented by fish oil therapy. The aim of this study was to determine b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683be96a92f3729f98e566628bf28358
https://doi.org/10.1046/j.1471-4159.1999.0730719.x

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Effect of streptozotocin-induced diabetes on rat liver Na+/K+-ATPase

Autor: Philippe Vague, Sandrine V. Pierre, Gérard Pieroni, Richard Planells, Marie-Josée Duran, Madeleine Bourdeaux, Alain Gerbi, Souad Sennoune, Joël-Paul Grillasca, Emmanuel Compe, Jean-Michel Maixent

Publikováno v: European Journal of Biochemistry. 267:2071-2078

Na+/K+-ATPase during diabetes may be regulated by synthesis of its alpha and beta subunits and by changes in membrane fluidity and lipid composition. As these mechanisms were unknown in liver, we studied in rats the effect of streptozotocin-induced d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d32e47ee9779abd90797b07aea7e5598
https://doi.org/10.1046/j.1432-1327.2000.01211.x

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